Clinical Chemistry
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Clinical Chemistry 45: 726-731, 1999;
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(Clinical Chemistry. 1999;45:726-731.)
© 1999 American Association for Clinical Chemistry, Inc.

Clinical Chemistry Forum

The Future of Molecular Genetic Testing

Debra G.B. Leonard

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-4283. Fax 215-662-7529;

The potential applications for genetic testing are immense, with most diseases having some aspect influenced by, if not directly caused by, changes in the genome of the patient. The translation of genetic information into medical applications will be influenced by our understanding of the human genome, technological advances, and social, ethical, and legal issues surrounding genetic testing. With time, new genetic information will be translated into clinical tests for the diagnosis of current illness and prediction of future disease risk, and will be used for the development of genetically directed therapies and preventive interventions. Most genetic testing will be highly automated, with only rare genetic disease tests performed manually. The challenge for the clinical genetic laboratory is to keep pace with this information explosion to provide state-of-the-art genetic testing and to ensure that the genetic test results are used in a morally, ethically, and socially responsible way.© 1999 American Association for Clinical Chemistry




The following articles in journals at HighWire Press have cited this article:


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Improved Method for Diagnosis of Charcot-Marie-Tooth Type 1A: Patent Pending?
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 Arch Pediatr Adolesc MedHome page
M. H. Farrell, L. K. Certain, and P. M. Farrell
Genetic Counseling and Risk Communication Services of Newborn Screening Programs
Arch Pediatr Adolesc Med, February 1, 2001; 155(2): 120 - 126.
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D. S. Young and D. G.B. Leonard
Issues in Genetic Testing
Clin. Chem., June 1, 1999; 45(6): 915 - 926.
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 Clin. Chem.Home page
D. S. Young
Issues in Genetic Testing
Clin. Chem., May 1, 1999; 45(5): 725 - 725.
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Copyright © 1999 by the American Association for Clinical Chemistry.