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Clinical Chemistry 49: 7-18, 2003; 10.1373/49.1.7
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(Clinical Chemistry. 2003;49:7-18.)
© 2003 American Association for Clinical Chemistry, Inc.


STARD Initiative

The STARD Statement for Reporting Studies of Diagnostic Accuracy: Explanation and Elaboration

Patrick M. Bossuyt1a, Johannes B. Reitsma1, David E. Bruns2,3, Constantine A. Gatsonis4, Paul P. Glasziou5, Les M. Irwig6, David Moher7, Drummond Rennie8,9, Henrica C.W. de Vet10 and Jeroen G. Lijmer1

1 Department of Clinical Epidemiology and Biostatistics, Academic Medical Center—University of Amsterdam, 1100 DE Amsterdam, The Netherlands.

2 Department of Pathology, University of Virginia, Charlottesville, VA 22903.

3 Clinical Chemistry, Washington, DC 20037.

4 Centre for Statistical Sciences, Brown University, Providence, RI 02912.

5 Centre for General Practice, University of Queensland, Herston QLD 4006, Australia.

6 Department of Public Health & Community Medicine, University of Sydney, Sydney NSW 2006, Australia.

7 Chalmers Research Group, Ottowa, Ontario, K1N 6M4 Canada.

8 Institute for Health Policy Studies, University of California, San Francisco, San Francisco, CA 94118.

9 Journal of the American Medical Association, Chicago, IL 60610.

10 Institute for Research in Extramural Medicine, Free University, 1081 BT Amsterdam, The Netherlands.

aAddress correspondence to this author at: Department of Clinical Epidemiology and Biostatistics, Academic Medical Center—University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands. Fax 31-20-6912683; e-mail p.m.bossuyt{at}amc.uva.nl.

The quality of reporting of studies of diagnostic accuracy is less than optimal. Complete and accurate reporting is necessary to enable readers to assess the potential for bias in the study and to evaluate the generalisability of the results. A group of scientists and editors has developed the STARD (Standards for Reporting of Diagnostic Accuracy) statement to improve the reporting the quality of reporting of studies of diagnostic accuracy. The statement consists of a checklist of 25 items and flow diagram that authors can use to ensure that all relevant information is present. This explanatory document aims to facilitate the use, understanding and dissemination of the checklist. The document contains a clarification of the meaning, rationale and optimal use of each item on the checklist, as well as a short summary of the available evidence on bias and applicability. The STARD statement, checklist, flowchart and this explanation and elaboration document should be useful resources to improve reporting of diagnostic accuracy studies. Complete and informative reporting can only lead to better decisions in healthcare.




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ANN INTERN MEDHome page
P. Whiting, A. W.S. Rutjes, J. B. Reitsma, A. S. Glas, P. M.M. Bossuyt, and J. Kleijnen
Sources of Variation and Bias in Studies of Diagnostic Accuracy: A Systematic Review
Ann Intern Med, February 3, 2004; 140(3): 189 - 202.
[Abstract] [Full Text] [PDF]


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Fam PractHome page
P. M Bossuyt, J. B Reitsma, D. E Bruns, C. A Gatsonis, P. P Glasziou, L. M Irwig, J. G Lijmer, D. Moher, D. Rennie, and H. C. de Vet
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
Fam. Pract., February 1, 2004; 21(1): 4 - 10.
[Abstract] [Full Text] [PDF]


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Clin. Chem.Home page
S. A. Dambinova, G. A. Khounteev, G. A. Izykenova, I. G. Zavolokov, A. Y. Ilyukhina, and A. A. Skoromets
Blood Test Detecting Autoantibodies to N-Methyl-D-aspartate Neuroreceptors for Evaluation of Patients with Transient Ischemic Attack and Stroke
Clin. Chem., October 1, 2003; 49(10): 1752 - 1762.
[Abstract] [Full Text] [PDF]


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JNCI J Natl Cancer InstHome page
J. G. Elmore, C. Y. Nakano, T. D. Koepsell, L. M. Desnick, C. J. D'Orsi, and D. F. Ransohoff
International Variation in Screening Mammography Interpretations in Community-Based Programs
J Natl Cancer Inst, September 17, 2003; 95(18): 1384 - 1393.
[Abstract] [Full Text] [PDF]


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Clin. Chem.Home page
S. Rothkrantz-Kos, M. P. van Dieijen-Visser, P. G.H. Mulder, and M. Drent
Potential Usefulness of Inflammatory Markers to Monitor Respiratory Functional Impairment in Sarcoidosis
Clin. Chem., September 1, 2003; 49(9): 1510 - 1517.
[Abstract] [Full Text] [PDF]


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Am. J. Roentgenol.Home page
P. M. Bossuyt, J. B. Reitsma, D. E. Bruns, C. A. Gatsonis, P. P. Glasziou, L. M. Irwig, J. G. Lijmer, D. Moher, D. Rennie, and H. C. W. de Vet
Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative
Am. J. Roentgenol., July 1, 2003; 181(1): 51 - 55.
[Abstract] [Full Text] [PDF]


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ANN INTERN MEDHome page
P. M. Bossuyt, J. B. Reitsma, D. E. Bruns, C. A. Gatsonis, P. P. Glasziou, L. M. Irwig, J. G. Lijmer, D. Moher, D. Rennie, H. C.W. de Vet, et al.
Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative
Ann Intern Med, January 7, 2003; 138(1): 40 - 44.
[Abstract] [Full Text] [PDF]


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BMJHome page
P. M Bossuyt, J. B Reitsma, D. E Bruns, C. A Gatsonis, P. P Glasziou, L. M Irwig, J. G Lijmer, D. Moher, D. Rennie, and H. C W de Vet
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
BMJ, January 4, 2003; 326(7379): 41 - 44.
[Abstract] [Full Text] [PDF]


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JAMAHome page
D. Rennie
Improving Reports of Studies of Diagnostic Tests: The STARD Initiative
JAMA, January 1, 2003; 289(1): 89 - 90.
[Full Text] [PDF]


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Clin. Chem.Home page
P. M. Bossuyt, J. B. Reitsma, D. E. Bruns, C. A. Gatsonis, P. P. Glasziou, L. M. Irwig, J. G. Lijmer, D. Moher, D. Rennie, and H. C.W. de Vet
Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative
Clin. Chem., January 1, 2003; 49(1): 1 - 6.
[Abstract] [Full Text] [PDF]


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Clin. Chem.Home page
D. E. Bruns
The STARD Initiative and the Reporting of Studies of Diagnostic Accuracy
Clin. Chem., January 1, 2003; 49(1): 19 - 20.
[Full Text] [PDF]


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RadiologyHome page
P. M. Bossuyt, J. B. Reitsma, D. E. Bruns, C. A Gatsonis, P. P. Glasziou, L. M. Irwig, J. G. Lijmer, D. Moher, D. Rennie, and H. C. W. de Vet
Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative
Radiology, January 1, 2003; 226(1): 24 - 28.
[Abstract] [Full Text] [PDF]




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