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Lipids, Lipoproteins, and Cardiovascular Risk Factors |
1 Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333.
Divisions of
2
Laboratory Sciences and
3
Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341.
4 Department of Laboratory Medicine, Children’s Hospital, Harvard Medical School, Boston, MA 02115.
5 Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115.
aAddress correspondence to this author at: Centers for Disease Control and Prevention, 1600 Clifton Rd., MS K66, Atlanta, GA 30333. Fax 770-488-8150; e-mail esf2{at}cdc.gov.
Background: The distribution of C-reactive protein (CRP) concentrations among children and young adults in the US is not known at present.
Methods: We used data from 3348 US children and young adults 3–19 years of age who participated in the National Health and Nutrition Examination Survey, 1999–2000, to describe the distribution of CRP concentrations, based on results obtained with a high-sensitivity latex-enhanced turbidimetric assay.
Results: The range of CRP concentrations was 0.1–90.8 mg/L (mean, 1.6 mg/L; geometric mean, 0.5 mg/L; median, 0.4 mg/L). CRP concentrations increased with age. Females 16–19 years of age had higher concentrations than males in this age range (P = 0.003). Mexican Americans had the highest CRP concentrations among the three major race or ethnic groups (P <0.001).
Conclusions: For the first time, these data describe the CRP concentration distribution among US children and young adults, based on results obtained with a high-sensitivity assay.
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