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Clinical Chemistry, Vol 5, 275-280, Copyright © 1959 by the American Association for Clinical Chemistry
1 Departments of Chemistry and Hematology, Mount Sinai Hospital, New York, N. Y., and Haskins Laboratories, New York, N. Y.
A microbiologic method based on Lactobacillus casei for assaying folic acid activity in serum is presented. The assay correlates directly with the clinical diagnosis. Comparison with formimino-L-glutamic acid determinations and other microbiologic assay methods shows the assay here described to yield a more dependable estimate of the folic acid status in humans.
Submitted on April 17, 1959
The following articles in journals at HighWire Press have cited this article:
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  R. Rej Clinical Chemistry through Clinical Chemistry: A Journal Timeline Clin. Chem., December 1, 2004; 50(12): 2415 - 2458. [Abstract] [Full Text] [PDF]
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 M. E. Shils, H. Baker, and O. Frank Blood Vitamin Levels of Long-Term Adult Home Total Parenteral Nutrition Patients: The Efficacy of the AMA-FDA Parenteral Multivitamin Formulation JPEN J Parenter Enteral Nutr, March 1, 1985; 9(2): 179 - 188. [Abstract] [PDF]
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 P. McPHEDRAN, M. G. BARNES, J. S. WEINSTEIN, and J. S. ROBERTSON Interpretation of Electronically Determined Macrocytosis Ann Intern Med, May 1, 1973; 78(5): 677 - 683. [Abstract] [PDF]
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 B. Hoogstratten, N. C. Leone, J. L. Shupe, D. A. Greenwood, and J. Lieberman Effect of Fluorides on Hematopoietic System, Liver, and Thyroid Gland in Cattle JAMA, April 5, 1965; 192(1): 26 - 32. [Abstract] [PDF]
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F. A. KLIPSTEIN Antibiotic Therapy in Tropical Sprue: The Role of Dietary Folic Acid in the Hematologic Remission Associated with Oral Antibiotic Therapy Ann Intern Med, October 1, 1964; 61(4): 721 - 728. [Abstract] [PDF]
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H. Baker, O. Frank, and H. Sobotka Mechanisms of Folic Acid Deficiency in Nontropical Sprue JAMA, January 11, 1964; 187(2): 119 - 121. [Abstract] [PDF]
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V. HERBERT, R. ZALUSKY, and C. S. DAVIDSON Correlation of Folate Deficiency with Alcoholism and Associated Macrocytosis, Anemia, and Liver Disease Ann Intern Med, June 1, 1963; 58(6): 977 - 988. [Abstract] [PDF]
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C. M. LEEVY, H. BAKER, and O. FRANK An Alkali Resistant Thermostable Hemopoietic Factor in Liver Ann Intern Med, January 1, 1963; 58(1): 37 - 46. [Abstract] [PDF]
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F. A. KLIPSTEIN Iron and Vitamin B12 Deficiency Following Subtotal Gastrectomy: Report of a Patient Developing Polycythemia Vera Following Treatment Ann Intern Med, July 1, 1962; 57(1): 133 - 140. [Abstract] [PDF]
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 F. C. CARTER, P. HELLER, G. SCHAFFNER, and R. J. KORN Formiminoglutamic Acid (FIGLU) Excretion in Hepatic Cirrhosis Arch Intern Med, July 1, 1961; 108(1): 41 - 46. [Abstract] [PDF]
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R. A. MARSHALL and J. H. JANDL Responses to "Physiologic" Doses of Folic Acid in the Megaloblastic Anemias Arch Intern Med, March 1, 1960; 105(3): 352 - 360. [Abstract] [PDF]
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