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Clinical Chemistry 5: 465-469, 1959;
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Clinical Chemistry, Vol 5, 465-469, Copyright © 1959 by the American Association for Clinical Chemistry

Concentration of Hyaluronic Acid in Synovial Fluid

Barry Decker 1, Warren F. McGuckin 1, Bernard F. McKenzie 1, and Charles H. Slocumb 1

1 Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

1. The concentration of hyaluronic acid in synovial fluid was determined by a modification of the Dische carbazole method for the determination of uronic acids.

2. The results of this determination in 80 specimens of normal and abnormal synovial fluid confirmed values reported by other methods.

3. An inverse relationship between the hyaluronic acid in the synovial fluid and the degree of synovitis was suggested.

Submitted on January 3, 1959






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Copyright © 1959 by the American Association for Clinical Chemistry.