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Clinical Chemistry 5: 557-565, 1959;
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Clinical Chemistry, Vol 5, 557-565, Copyright © 1959 by the American Association for Clinical Chemistry

Studies of Blood Lipid Fractions of Quiescent Rheumatic Fever Patients and Their Siblings

Harold D. Appleton 1, Alvin F. Coburn 1, and Yale L. Meltzer 1

1 Department of Pediatrics, The New York Medical College, and the Department of Clinical Chemistry, Division of Pathology, Metropolitan Hospital, New York, N. Y.

Three phospholipid fractions have been determined in plasmas of quiescent rheumatic children and their siblings of similar ages.

The method for determining blood lecithin gave reproducible results, and the lipid fraction appeared indicative of difference in levels of blood lipids between rheumatic and nonrheumatic children.

In this series of lecithin determinations only one rheumatic subject had a high normal level and only one sibling (presumably nonrheumatic) had a low level.

The difference in mean nonfasting lecithin plasma levels between rheumatic subjects and siblings was 0.36 mMol./L. Similarly, the lecithin level of each of the nonrheumatic siblings in this series averaged 0.41 mMol./L. higher than that of the corresponding quiescent rheumatic child. In both of these differences P <0.05.

Submitted on July 22, 1959






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Copyright © 1959 by the American Association for Clinical Chemistry.