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Clinical Chemistry 5: 623-633, 1959;
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Clinical Chemistry, Vol 5, 623-633, Copyright © 1959 by the American Association for Clinical Chemistry

A Simplified Procedure for the Routine Determination of Uric Acid

Mohinder P. Sambhi 1 and Arthur Grollman 1

1 Department of Experimental Medicine, The University of Texas Southwestern Medical School, Dallas, Texas.

1. A method for the colorimetric determination of serum uric acid is described which involves the adsorption of uric acid by an ionexchange resin and the addition of N-ethylmaleimide to remove interfering chromogens.

2. The procedure is simple, accurate, and suitable for routine clinical use.

3. The clinical significance of serum uric acid levels is discussed.

Submitted on May 19, 1959






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Copyright © 1959 by the American Association for Clinical Chemistry.