Clinical Chemistry
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Clinical Chemistry 53: 1665-1675, 2007. First published July 27, 2007; 10.1373/clinchem.2006.084707
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(Clinical Chemistry. 2007;53:1665-1675.)
© 2007 American Association for Clinical Chemistry, Inc.


Point-of-Care Testing

Improving Healthcare Accessibility through Point-of-Care Technologies

Edited on behalf of the National Institute of Biomedical Imaging and Bioengineering/National Heart, Lung, and Blood Institute/National Science Foundation Workshop Faculty1, Christopher P. Price2, Larry J. Kricka3,a

1 NIBIB/National Heart, Lung and Blood Institute/National Science Foundation workshop faculty (see Appendix).
2 Department of Clinical Biochemistry, University of Oxford, John Radcliffe Hospital, Oxford, UK.
3 Division of Discovery Science and Technology, National Institute of Biomedical Imaging and Bioengineering, NIH, Department of Health and Human Services, Bethesda, MD.

aAddress correspondence to this author at: Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 7.103 Founders Pavilion, 3400 Spruce St., Philadelphia, PA 19104. Fax 215-662-7529; e-mail kricka{at}mail.med.upenn.edu.

Background: The NIH is committed to improving healthcare quality in the US and has set up initiatives to address problems such as the fragmented nature of healthcare provision. A hypothesis has been developed that testing closer to the point at which care is delivered may reduce fragmentation of care and improve outcomes.

Methods: The National Institute of Biomedical Imaging and Bioengineering (NIBIB), the NIH’s National Heart, Lung, and Blood Institute, and the National Science Foundation sponsored a workshop, "Improving Health Care Accessibility through Point-of-Care Technologies," in April 2006. The workshop assessed the clinical needs and opportunities for point-of-care (POC) technologies in primary care, the home, and emergency medical services and reviewed minimally invasive and noninvasive testing, including imaging, and conventional testing based on sensor and lab-on-a-chip technologies. Emerging needs of informatics and telehealth and healthcare systems engineering were considered in the POC testing context. Additionally, implications of evidence-based decision-making were reviewed, particularly as it related to the challenges in producing reliable evidence, undertaking regulation, implementing evidence responsibly, and integrating evidence into health policy.

Results: Many testing procedures were considered to be valuable in the clinical settings discussed. Technological solutions were proposed to meet these needs, as well as the practical requirements around clinical process change and regulation. From these considerations, a series of recommendations was formulated for development of POC technologies based on input from the symposium attendees.

Conclusion: NIBIB has developed a funding initiative to establish a Point-of-Care Technologies Research Network that will work to bridge the technology/clinical gap and provide the partnerships necessary for the application of technologies to pressing clinical needs in POC testing.




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