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Clinical Chemistry 6: 153-161, 1960;
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Clinical Chemistry, Vol 6, 153-161, Copyright © 1960 by the American Association for Clinical Chemistry

A Scheme for the Rapid Identification in Urine of Commonly Used Sedatives, Hypnotics, and Tranquilizers

Georges Sobolewski 1 and Guy Nadeau 1

1 Laboratoire de Biochimie, Hôpital Saint-Michel Archange, Québec, Canada.

A procedure is described to identify common sedatives, hypnotics, and ataractics in 20 ml. of urine, with the aid of four extractions and five relatively simple reactions. The whole scheme, which involves no special equipment and requires about 2 hours, will detect the drugs at the usual therapeutic levels and, hence, has been found convenient not only in acute drug intoxication, but also in ascertaining that patients comply with the prescribed medication.




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