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Clinical Chemistry 6: 223-227, 1960;
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Clinical Chemistry, Vol 6, 223-227, Copyright © 1960 by the American Association for Clinical Chemistry

Effects of Hemolysis on Serum Electrolyte Values

Alan Mather 1 and Nellie Ray Mackie 1

1 Research Department, The Memorial Hospital, Wilmington, Del.

The correction of serum potassium and phosphate values for erythrocyte contribution arising from hemolysis during blood collection may be made with a fair degree of confidence by evaluating the cellular potassium and phosphorus from the serum hemoglobin. The correction for potassium is appreciable, about 3.3 mEq./L. for each gram of liberated hemoglobin; the correction for phosphorus in fresh specimens is about one tenth as great, and may ordinarily be neglected.

Submitted on August 31, 1959




The following articles in journals at HighWire Press have cited this article:


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Clin. Chem.Home page
R. Hawkins
Variability in Potassium/Hemoglobin Ratios for Hemolysis Correction
Clin. Chem., May 1, 2002; 48(5): 796 - 796.
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