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Clinical Chemistry 6: 495-500, 1960;
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Clinical Chemistry, Vol 6, 495-500, Copyright © 1960 by the American Association for Clinical Chemistry

Use of a New Assay in a Study of Serum Alkaline Phosphatase Levels in 2000 Hospital Patients

Arthur L. Babson 1, Prunella A. Read 1, George E. Phillips 1, and Hugh F. Luddecke 2

1 Department of Biochemistry, The Warner-Lambert Research Institute, Morris Plains, N. J.
2 Department of Pathology, Morristown Memorial Hospital, Morristown, N. J.

Serum alkaline phosphatase determinations performed with a commercially available tablet procedure for rapid semiquantitative assay gave results that were found to be reliable and in agreement with quantitative assays performed by the Bodansky procedure.

In a study of the sera of 2000 hospital patients, more than 70 per cent of all the assays requested yielded normal values. Since precise determinations in the normal range are generally not required for clinical interpretation, routine use of the semiquantitative test for preliminary screening would have eliminated this percentage of the tedious quantitative assays.

Submitted on December 4, 1959






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Copyright © 1960 by the American Association for Clinical Chemistry.