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Clinical Chemistry 6: 578-581, 1960;
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Clinical Chemistry, Vol 6, 578-581, Copyright © 1960 by the American Association for Clinical Chemistry

Vitamin B12, in Human Blood and Serum

I. Comparison of Microbiologic Assays Using Normal Subjects

Herman Baker 1, Oscar Frank 1, Inez Pasher 1, and Harry Sobotka 1

1 Department of Chemistry, Mount Sinai Hospital, New York.

A comparison of microbiologic assays for vitamin B12 in whole blood or serum was carried out with four B12-requiring microorganisms, Escherichia coli 113-3, Lactobacillus leichmannii ATCC No. 7839, Euglena gracilis, strain Z, and Ochromonas malhamensis. B12 values in whole blood and serum for normal subjects are given. The value of microbiologic assays is discussed.

Submitted on June 20, 1960






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Copyright © 1960 by the American Association for Clinical Chemistry.