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Clinical Chemistry 8: 626-629, 1962;
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Clinical Chemistry, Vol 8, 626-629, Copyright © 1962 by the American Association for Clinical Chemistry

Variations in Levels of Transaminases and Lactic Dehydrogenase in Bank Blood

Leonard V. Crowley 1

1 Department of Pathology, College of Medicine, University of Vermont, and The Vermont-New Hampshire Red Cross Regional Blood Center, Burlington, Vt.

Results of the assay of transaminases and lactic dehydrogenase in blood, proposed as a screening procedure for subclinical hepatitis in blood donors, show that the method of sampling influences the analytic results. Determinations of GOT and GPT may prove useful if made on specimens separated from cells soon after collection. Plasma in contact with cells from blood preserved in acid citrate dextrose solution appears to yield good results up to 21 days. Lactic-dehydrogenase levels are of limited value for this screening.






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Copyright © 1962 by the American Association for Clinical Chemistry.