Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 43: 540-541, 1997;
This Article
Right arrow Full Text
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Heshmati, H. M.
Right arrow Articles by Turpin, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Heshmati, H. M.
Right arrow Articles by Turpin, G.
Related Collections
Right arrow Evidence Based Laboratory Medicine and Test Utilization
Right arrow Proteomics and Protein Markers
(Clinical Chemistry. 1997;43:540-541.)
© 1997 American Association for Clinical Chemistry, Inc.

Technical Briefs

Serum Neuron-Specific Enolase in Patients with Pituitary Adenoma

Hassan M. Heshmati1,a, Yvan Touitou2, Luc Foubert1, William F. Young, Jr.3, Eric Bruckert1 and Gérard Turpin1

1 Dept. of Endocrinol., Pitié Hospital, and
2 Dept. of Biochem., Pitié School of Medicine, 75013 Paris, France;
3 Div. of Endocrinol., Mayo Clinic and Mayo Foundation, Rochester, MN 55905;
a address for correspondence: Endocrine Res. Unit, 5–164 West Joseph, Mayo Clinic, Rochester, MN 55905: fax 507-255-4828, e-mail heshh@mayo.edu

Neuron-specific enolase (NSE) is an isomer of the widely distributed glycolytic enzyme 2-phospho-D-glycerate hydrolase (EC 4.2.1.11), composed of two subunits, {alpha} and {gamma}. NSE is localized in neurons and in peripheral and central neuroendocrine cells ["amine precursor uptake and decarboxylation" cells (APUD)] (1). Tumors arising from APUD cells may contain high amounts of NSE detectable by both immunostaining of tumor cells and radioimmunological measurement of extractable enzyme (2)(3). These tumors include small-cell lung cancer (4)(5), neuroblastoma (6), pancreatic islet cell cancer (7), . . . [Full Text of this Article]


Acknowledgments


References






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1997 by the American Association for Clinical Chemistry.