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Clinical Chemistry 46: 863-864, 2000;
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(Clinical Chemistry. 2000;46:863-864.)
© 2000 American Association for Clinical Chemistry, Inc.

Technical Briefs

Serum Concentrations of Intact Parathyroid Hormone in Healthy Children

Michele Cioffia, Maurizio Corradino1, Patrizio Gazzerro1, Maria-Teresa Vietri1, Catia Di Macchia1, Anna Contursi1, Rosalia Colicigno1, Teodoro Catalano1 and Anna M. Molinari1

1 Institute General Pathology and Oncology, Second School of Medicine of Naples, 80138 Naples, Italy
a address correspondence to this author at: Istituto di Patologia Generale e Oncologia, Seconda Università degli Studi di Napoli, Via S. Andrea delle Dame 2, 80138 Napoli, Italy

Parathyroid hormone (PTH) plays an important role in calcium homeostasis by maintaining the concentration of ionized calcium within the precise limits necessary to achieve metabolic and neuroregulatory functions of this essential mineral (1)(2)(3). PTH produces calcium mobilization from the large skeletal stores into the extracellular fluid, increases absorption of dietary calcium, and decreases renal clearance of urinary calcium (3)(4). Serum PTH assays are an important aid in the assessment of calcium metabolism disorders. The aim of this study was to determine serum intact PTH in a large group of healthy children according to their ages.

We selected 794 healthy children (409 girls, 385 boys), ages 2–16 years, arriving for routine clinical check-ups in the Department of Pediatrics over 4 years (1994–1998). Sample sera were taken at 0800 from non-fasting children.

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[Abstract] [Full Text] [PDF]


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