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Clinical Chemistry 47: 2181, 2001;
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(Clinical Chemistry. 2001;47:2181.)
© 2001 American Association for Clinical Chemistry, Inc.

Letters

ß-Trace Protein Is Not Better than Cystatin C as an Indicator of Reduced Glomerular Filtration Rate

Friedrich Priem1a, Harald Althaus2, Klaus Jung3 and Pranav Sinha1

Departments of
1 Laboratory Medicine and
3 Urology, University Hospital Charité Humboldt University Berlin, 10098 Berlin, Germany
2 Dade Behring Marburg GmbH, 35001 Marburg, Germany

aAddress correspondence to this author at: Institut für Laboratoriumsmedizin und Pathobiochemie, Universitätsklinikum Charité, Schumannstrasse 20/21, D-10117 Berlin, Germany. Fax 49-30-450569912;


To the Editor:

Recent studies suggest that serum cystatin C [reviewed in Refs. (1)(2)] and ß-trace protein (3)(4) identify reductions in glomerular filtration rate (GFR) better than creatinine does. Woitas et al. (5) compared for the first time the diagnostic performance of cystatin C, ß-trace protein, ß2-microglobulin, and creatinine in relation to inulin clearance. They noted that we reported a higher diagnostic accuracy of ß-trace protein in a study with 115 diabetic patients (4). As explanation, Woitas et al. (. . . [Full Text of this Article]


References




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
L. Pucci, S. Triscornia, D. Lucchesi, C. Fotino, G. Pellegrini, E. Pardini, R. Miccoli, S. Del Prato, and G. Penno
Cystatin C and Estimates of Renal Function: Searching for a Better Measure of Kidney Function in Diabetic Patients
Clin. Chem., March 1, 2007; 53(3): 480 - 488.
[Abstract] [Full Text] [PDF]

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 Clin. Chem.Home page
A. R. Huber and L. Risch
Recent Developments in the Evaluation of Glomerular Filtration Rate: Is There a Place for {beta}-Trace?
Clin. Chem., August 1, 2005; 51(8): 1329 - 1330.
[Full Text] [PDF]

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 Clin. Chem.Home page
G. Filler, F. Priem, N. Lepage, P. Sinha, I. Vollmer, H. Clark, E. Keely, M. Matzinger, A. Akbari, H. Althaus, et al.
{beta}-Trace Protein, Cystatin C, {beta}2-Microglobulin, and Creatinine Compared for Detecting Impaired Glomerular Filtration Rates in Children
Clin. Chem., May 1, 2002; 48(5): 729 - 736.
[Abstract] [Full Text] [PDF]


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