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Technical Briefs |
1
Department of Analytical Chemistry, Faculty of Pharmacy, Ege University, 35100 Bornova, Izmir, Turkey; Departments of
2
Biochemistry and
3
Neonatal Unit, Izmir Social Security Institution Tepecik Educational Hospital, 35120 Tepecik, Izmir, Turkey;
aauthor for correspondence: e-mail ozsozs@pharm.ege.edu.tr
In newborns, hypoglycemia must be detected in venous specimens with a wide range of hematocrits and oxygen tensions. The need for a simple and rapid test for glucose to meet special applications such as those found in pediatric wards has been suggested frequently (1)(2)(3)(4). Simple tests are available, but their use in neonatal units has usually not been recommended, reflecting, at least in part, the influence on results of sample hematocrit and oxygen tension (5)(6).
The Precision G System is a new instrument with a new electrode strip (G2b), which is purported to address many of the shortcomings found in previous generations of biosensors. The bioactive component of Precision G System is glucose oxidase. This is also used in many other glucose measuring systems (7). The component that makes the Precision G System unique is the signal transducer and mediator ferrocene (8).
We performed laboratory and clinical evaluations of the Precision G System with the G2b test strips to determine its suitability for use in a neonatal unit. We compared the performance of the Precision G System with a laboratory method using venous specimens with a wide range of hematocrits taken from patients in a neonatal intensive care unit.
After approval from the Institutional Review Board of the Izmir Social Security Institute (SSK) Tepecik Education Hospital, the instrument was permitted to be used in
Acknowledgments
References
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