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Clinical Chemistry 48: 2294-2296, 2002;
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(Clinical Chemistry. 2002;48:2294-2296.)
© 2002 American Association for Clinical Chemistry, Inc.

Letters

Comparison of Serum and Heparin-Plasma Samples in Different Generations of Dimension Troponin I Assay

Romolo M. Dorizzia, Marco Caputo, Anna Ferrari, Lorella Lippa and Paolo Rizzotti

Clinical Chemistry, and Hematology Laboratory, Hospital of Verona, Piazzale A. Stefani 1, 37126 Verona, Italy

aAuthor for correspondence. Fax 39-045-8072156; e-mail romolo.dorizzi@mail.azosp.vr.it.

The first 20% of the full text of this article appears below.


To the Editor:

An editorial in the June issue of the Journal pointed out the usefulness of plasma instead of serum for cardiac troponin I (cTnI) determinations. However, because some analytical systems yield significant differences between serum and plasma troponin concentrations, the author of the editorial advocates more peer-reviewed studies before new assays are implemented in hospital-based laboratories (1). In September 2001 and March 2002, we carried out two comparison studies of cTnI measurements in plasma and serum samples, using different generations of the same assay (Cardiac Troponin-I Flex; Dade Behring). Both serum and plasma samples have been reported as suitable for cTnI determinations in the first (2) and second (3) generations of the assay. We collected two different series of 39 blood samples from patients admitted to the intensive care unit of our . . . [Full Text of this Article]




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
M. Panteghini and F. Pagani
On the Comparison of Serum and Plasma Samples in Troponin Assays
Clin. Chem., May 1, 2003; 49(5): 835 - 836.
[Full Text]


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