Clinical Chemistry
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Clinical Chemistry 48: 2296-2297, 2002;
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(Clinical Chemistry. 2002;48:2296-2297.)
© 2002 American Association for Clinical Chemistry, Inc.


Letters

Falsely Increased Free Triiodothyronine in Sera Stored in Serum Separator Tubes

Aytül Sadan Kilinç, Ahmet Düzoylum, Cenk Firat Uncugil and Dogan Yücela

Biochemistry Laboratory, SB Ankara Education, and Research Hospital, Ankara 06340, Turkey

aAddress correspondence to this author at: Biochemistry Laboratory, SB Ankara Egitim ve Arastirma Hastanesi, Ankara 06340, Turkey. Fax 90-312-3621857; e-mail doyucel@yahoo.com.

The first 20% of the full text of this article appears below.


To the Editor:

We recently encountered inappropriately increased free triiodothyronine (FT3) concentrations when blood specimens were collected in glass serum separator tubes (SSTTM; Vacutainer®). Although Banfi and Pontillo (1) reported no differences between plain and gel-containing tubes until 72 h after blood collection for FT3 [and thyrotropin (TSH) and free thyroxine (FT4)], we investigated the effects of storing specimens in gel-containing tubes on these analytes.

We collected blood specimens from 11 healthy volunteers in both SST (16 x 100 mm) and plain glass (13 x 100 mm) Vacutainer Tubes. All specimens were allowed to clot for 30 min at room temperature before centrifugation at 1300g for 10 min. Sera separated in SST tubes remained on the separator gel, whereas sera separated in plain tubes were transferred into 13 x 100 mm plain tubes (Vacutainer) for storage. All SST specimens and transferred control . . . [Full Text of this Article]







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