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Clinical Chemistry 49: 1711-1712, 2003; 10.1373/49.10.1711
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(Clinical Chemistry. 2003;49:1711-1712.)
© 2003 American Association for Clinical Chemistry, Inc.

Letters

Response to the Comments of K. Day and J. Zakowski on "Clinical Capillary Zone Electrophoresis of Serum Proteins: Balancing High Sensitivity and High Specificity"

Godelieve Mariën and Xavier Bossuyta

Laboratory Medicine and Immunology, University Hospital Leuven, Herestraat 49, B-3000 Leuven, Belgium

aAuthor for correspondence.

The first 20% of the full text of this article appears below.


To the Editor:

We wish to respond to the comments of K. Day and J. Zakowski concerning our letter in the August issue of Clinical Chemistry (1)(2) in which we discussed the capabilities of agarose gel electrophoresis/immunofixation and capillary zone electrophoresis for detecting rare monoclonal proteins.

We first wish to respond to their comments that enhanced resolution often detects peaks that previously were not readily observable, that the gamma zone migrates more rapidly in CZE Version 1.6.02 and may be misinterpreted as a peak . . . [Full Text of this Article]




The following articles in journals at HighWire Press have cited this article:


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I. Infusino, P. Luraschi, M. Panteghini, and C. Franzini
Pretreatment of serum with penicillamine: effects on capillary electrophoresis patterns and on immunonephelometric measurement of immunoglobulins.
Clin. Chem., April 1, 2006; 52(4): 772 - 774.
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P. Luraschi, I. Infusino, I. Zorzoli, G. Merlini, C. Fundaro and, and C. Franzini
Heavy Chain Disease Can Be Detected by Capillary Zone Electrophoresis
Clin. Chem., January 1, 2005; 51(1): 247 - 249.
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X. Bossuyt and G. Marien
False-Negative Serum Protein Electrophoresis in a Sample with an IgM Monoclonal Protein by Semiautomated Gel Electrophoresis
Clin. Chem., January 1, 2005; 51(1): 270 - 270.
[Full Text] [PDF]


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