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Clinical Chemistry 50: 1878, 2004; 10.1373/clinchem.2004.037275
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(Clinical Chemistry. 2004;50:1878.)
© 2004 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Biological Variation of Procalcitonin in Healthy Individuals

Alessandra Barassia, Francesco Pallotti and GianVico Melzi d’Eril

1 Dipartimento di Scienze Biomediche, Sperimentali e Cliniche, Università degli Studi dell’Insubria, Varese, Italy

aAddress correspondence to this author at: via Dunant 5, 21100 Varese, Italy. Fax 39-0332278565; e-mail alessandra.barassi@tin.it.

The first 20% of the full text of this article appears below.


To the Editor

Procalcitonin (PCT) is a stable 116-amino acid precursor molecule to the hormone calcitonin. High serum concentrations have been reported in patients with severe systemic bacterial or fungal, but not viral, infections (1).

Information on the biological variation of PCT is not available; this is limiting because the clinical utility of laboratory data can be affected by physiologic variation (2). Here we report the results of a study to determine the biological variation of PCT.

To investigate the biological variation of this analyte, we followed the same protocol that we used for the study of the biological variation of N-terminal pro-B-type . . . [Full Text of this Article]




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Procalcitonin in healthy individuals
Nils G Morgenthaler, et al.
Clinical Chemistry Online, 5 Oct 2004 [Full text]

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