Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 52: 334-335, 2006; 10.1373/clinchem.2005.062109
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Web of Science (1)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Silva, F. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Silva, F. O.
Related Collections
Right arrow Molecular Diagnostics and Genetics
Right arrow General Clinical Chemistry
Right arrow Automation and Analytical Techniques
(Clinical Chemistry. 2006;52:334-335.)
© 2006 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Microwave-Assisted Derivatization of Glucose and Galactose for Gas Chromatographic Determination in Human Plasma

Fabiano O. Silva

1 Departamento de Química, Universidade Federal, de Minas Gerais, Av. Antonio Carlos, 6627, Belo Horizonte-MG, 31270-901, Brazil, Fax 55-31-3499-5700 E-mail drhtcl@yahoo.com

The first 20% of the full text of this article appears below.


To the Editor:

Monosaccharides are usually analyzed by use of automatic monitors or enzymatic immunoassays. However, gas chromatography (GC) is an accurate and precise technique for galactose quantification (1), and it is regarded as a reference method for glucose (2). GC procedures require a long derivatization time in 2 consecutive reactions of 60–90 min to generate the aldonitrile pentaacetate derivative. Fast derivatization techniques are often requested today because the bottleneck for sample throughput has moved from analysis to sample preparation. Recently, we dramatically decreased the derivatization time for sugars (mono- and disaccharides) in GC analysis (3) by using trimethylsilyl-oxime . . . [Full Text of this Article]






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the American Association for Clinical Chemistry.