Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 53: 1555-1556, 2007; 10.1373/clinchem.2007.088435
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via ISI Web of Science (2)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kitchen, S.
Right arrow Articles by Walker, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kitchen, S.
Right arrow Articles by Walker, I.
Related Collections
Right arrow Laboratory Management
Right arrow Hemostasis and Thrombosis
(Clinical Chemistry. 2007;53:1555-1556.)
© 2007 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Quality Assessment of CoaguChek Point-of-Care International Normalized Ratio Monitors: A Note of Caution

Steve Kitchena, Dianne Kitchen, Ian Jennings, Tim Woods and Isobel Walker

UK NEQAS Blood Coagulation, Rutledge Mews, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, United Kingdom

aAddress correspondence to this author at: UK NEQAS Blood Coagulation, Rutledge Mews, 3 Southbourne Rd., Sheffield Teaching Hospitals NHS Foundation Trust S10 2QN, United Kingdom. Fax 44-0-114-271-2149; e-mail Steve.kitchen@sth.nhs.uk.

The first 20% of the full text of this article appears below.


To the Editor:

In a recent publication Poller et al. (1) described quality assessment (QA) of CoaguChek (CUC) point-of-care (POC) international normalized ratio (INR) monitors and compared 2 procedures. The study compared the proportion of 523 CUC monitors having unsatisfactory performance as indicated by either a >15% deviation of INR results from the INR assigned to 5 lyophilized QA plasmas or a >15% deviation from the overall median of INRs obtained on the monitors included in the survey. The INRs assigned to QA plasmas had been derived from a full calibration in compliance with WHO-recommended procedures and a local mean normal prothrombin time.

The CUC device is calibrated by the manufacturer for use with non-anticoagulated whole blood. Patients using the device analyze whole blood and not plasma. Furthermore, the calibration procedure employed by Poller et al. (1) used whole blood samples to derive the International Sensitivity Index for assigning INRs to the lyophilized plasma samples. . . . [Full Text of this Article]






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American Association for Clinical Chemistry.