Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 54: 770, 2008; 10.1373/clinchem.2007.094177
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pesce, M. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pesce, M. A.
Related Collections
Right arrow Citation Classics
(Clinical Chemistry. 2008;54:770.)
© 2008 American Association for Clinical Chemistry, Inc.

Citation Classics

Quantifying Protein in Cerebrospinal Fluid and Urine: Success Achieved

Michael A. Pesce1

1 New York Presbyterian Hospital; Columbia University Medical Center; New York, NY.

aAddress correspondence to the author at: New York Presbyterian Hospital, Columbia-University Medical Center, 622 West 168th Street, CHS-2-224, New York, NY 10032-3720. E-mail map8@columbia.edu.

The first 20% of the full text of this article appears below.

Featured Article: Pesce MA, Strande CS. A new micromethod for determination of protein in cerebrospinal fluid and urine. Clin Chem 1973;11:1265–7.1

This paper described a dye-binding micromethod for measuring protein concentrations in cerebrospinal fluid and urine. The method involved coprecipitation of the proteins with a Ponceau S dye trichloroacetic acid solution, dissolving the protein precipitate in dilute sodium hydroxide, and measuring the absorbance at 560 nm. This method was rapid, easy to use, and required a specimen volume of 5–50 µL.

I began my career as a clinical chemist in 1971 in the pediatric microchemistry laboratory at Columbia Presbyterian Medical Center. This laboratory served the newborn, infant, and child population of Babies Hospital, . . . [Full Text of this Article]






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2008 by the American Association for Clinical Chemistry.