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Clinical Chemistry 54: 771-772, 2008; 10.1373/clinchem.2007.093716
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(Clinical Chemistry. 2008;54:771-772.)
© 2008 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Anomalous Flotation of Separator Gel: Density or Viscosity?

María Fatása, Pablo Franquelo and Ricardo Franquelo

Department of Clinical Chemistry and Laboratory Medicine, Hospital Virgen de la Luz, Cuenca, Spain

aAddress correspondence to this author at: Department of Clinical Chemistry and Laboratory Medicine Hospital Virgen de la Luz 16002 Cuenca, Spain Fax 34-969-220601 e-mail mariafatas@hotmail.com

The first 20% of the full text of this article appears below.


To the Editor:

Blood collection tubes containing a thixotropic polyester gel are widely used for clinical laboratory testing. The gel, because of its intermediate density (1.04 g/cm3), physically separates the liquid component of the blood from the cells (densities of 1.03 and 1.09 g/cm3 respectively) after centrifugation, and forms a barrier between the liquid phase and the cells. However, recent cases have been reported in which anomalies in the formation of this separating barrier can occur(1). Although the number of reported cases seems low, the impact on cost and the risk of reporting misleading values is substantial(1). Different interpretations have been proposed regarding whether the anomalous flotation of the gel is a matter of density or viscosity of the serum/plasma(. . . [Full Text of this Article]






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Copyright © 2008 by the American Association for Clinical Chemistry.