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Point of care testing of thyroid-stimulating hormone (TSH) and free thyroxine (FT4)a new clinical service possibility. Fremner, E; Kalerud, B.; Larsson, L; Department of Clinical Chemistry, Motala Hospital, Motala, Sweden; University Hospital of Linköping, Sweden
Former esoteric tests as i.e. HbA1c can now be performed in primary health care. At the same time the number of hospital beds are reduced and patients are transferred to out-patient clinics. Furthermore there is an increase in the elderly population with non-specific clinical symptoms attending these clinics.
Therefore we investigated the MiniVidas® (Bio Merieux) analytical quality for TSH and FT4 and its effect on turn-around time (TAT) in a primary health care center.
A good overall correlation was found between IMS® (Abbott) and MiniVidas® for both analytes (TSH: y=1.13 x + 0.26, r2 = 0.98; FT4: y = 0.83 x + 1.70, r2 = 1). The internal quality control with assigned values for TSH (3.60 - 4.80 mU/L) and FT4 (18.0 - 26.0 pmol/L) was analysed once every day and had a CV of 4.8% (mean +/- SD = 4.25 +/- 0.20 mU/L, n = 52) and 7.6% (mean +/- SD = 23.8 +/- 1.8 pmol/L, n = 53) respectively.
The external control from Labquality (Finland) indicated accurate results for both TSH and FT4. TAT from sampling to ready result was about 50 minutes,a considerable improvement for the patient, who earlier had to wait daysweeks for their results. In conclusion the MiniVidas® TSH and FT4 analytes performed within clinically acceptable ranges of accuracy and imprecision and offers a new practical possibility for near patient service.
In a reply to a Letter to the Editor (1997;43:1463), the first author's name, M. Muglia, was misspelled.
In the article by G. Morineau, A. Boudi, A. Barka, M.
Gourmelen, F. Degeilh, N. Hardy, et al., entitled "Radioimmunoassay
of cortisone in serum, urine, and saliva to
assess the status of the cortisolcortisone shuttle," 1997;43:1397407,
the name of an author listed in reference 42 and mentioned
in the text on p. 1404 was misspelled. Instead of Fejs-Toth, it should
be Fejes-Toth. In addition, on p. 1399, "The specific
activity...25 TBq/mmol (450 mCi/mmol)." should be "The specific
activity...25 TBq/mmol (675 Ci/mmol)." Also, some of the column
headings in Table 2
were incorrectly placed. The corrected Table
is presented on the facing page:
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References
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