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Letters |
Chiron Diagnostics Corp., 63 North St., Medfield, MA 02052-1688
To the Editor:
The symposium Preparing for Critical Care Analyses in the 21st Century was held February 1821, 1996, at the Hilton Waikoloa Village, Waikoloa, HI. This symposium, the 16th in a series, was cosponsored by the AACC Electrolyte/Blood Gas Division and the Japan Society for Clinical Chemistry, Committee for Blood Gases and Electrolytes. Approximately 100 scientists representing 14 countries attended the meeting, which was dedicated to the memory of Graham M. Widdowson, a founding member of the AACC Division.
Five one-half day sessions focused on the rapidly changing field of critical care analysis: new technologies on the horizon, and how they will be implemented in laboratory practice in the near future. The first session, New Perspectives on Blood Gas Analysis, chaired by Onno W. vanAssendelft (Centers for Disease Control and Prevention, Atlanta, GA) featured a review of recent work in the development of blood substitutes, as well as data from CO-oximetry and hemoglobin determinations in the presence of blood substitutes. Also covered in this session were the correct usage of analytical indices to evaluate blood oxygenation in the lungs, and new developments and findings in the areas of quality control and sample handling as related to blood gas determinations. The session entitled Point of Care TestingTechnology and Clinical Objectives, led by Mary Burritt (Mayo Clinic, Rochester, MN), presented and took a critical look at the economic models used to justify point-of-care testing. This was followed by a review of new instrumentation for point-of-care testing, and the experiences of two clinicians using one of these systems at their institutions. Two sessions focused on Sensor Technologies and Analytes for the Future. These sessions were chaired by Kazuo Yasuda (Hitachi, Tokyo, Japan) and Jay Johnson (Yellow Springs Instruments, Yellow Springs, OH). A variety of emerging sensing technologies for critical care were described, including: optical sensors for blood gases and electrolytes (and their application in near-patient situations) and biosensors for measurement of glucose, lactate, ionized magnesium, and DNA in blood and serum. Noninvasive sensing technologies for glucose, and anesthetic agents were also introduced. The final session of the meeting was devoted to StandardizationReference Materials and Methods and was cochaired by Katsuhiko Kuwa (University of Tsukuba, Tsukuba, Japan) and Charles Sachs (University of Paris, Paris, France). Ongoing efforts at standardizing the measurement of electrolytes in Japan and the US were described in detail. New proposals for standardizing the measurement and reporting of ionized magnesium, glucose, and lactate were also introduced.
The Proceedings of the meeting have been published and are available for a small cost to cover printing and postage. I may be contacted at: phone 508-359-3521, fax 508-359-3955, e-mail paul.dorazio@chirondiag.com, for further information.
The following articles in journals at HighWire Press have cited this article:
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S. E. Lipshultz, M. J. G. Somers, S. R. Lipsitz, S. D. Colan, K. Jabs, and N. Rifai Serum Cardiac Troponin and Subclinical Cardiac Status in Pediatric Chronic Renal Failure Pediatrics, July 1, 2003; 112(1): 79 - 86. [Abstract] [Full Text] [PDF] |
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B. J. Freda, W. H. W. Tang, F. Van Lente, W. F. Peacock, and G. S. Francis Cardiac troponins in renal insufficiency: Review and clinical implications J. Am. Coll. Cardiol., December 18, 2002; 40(12): 2065 - 2071. [Abstract] [Full Text] [PDF] |
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F. S. Apple, M. M. Murakami, L. A. Pearce, and C. A. Herzog Predictive Value of Cardiac Troponin I and T for Subsequent Death in End-Stage Renal Disease Circulation, December 3, 2002; 106(23): 2941 - 2945. [Abstract] [Full Text] [PDF] |
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M Lund, J.K French, R.N Johnson, B.F Williams, and H.D White Serum troponins T and I after elective cardioversion Eur. Heart J., February 1, 2000; 21(3): 245 - 253. [Abstract] [PDF] |
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A. H.B. Wu, F. S. Apple, W. B. Gibler, R. L. Jesse, M. M. Warshaw, and R. Valdes Jr. National Academy of Clinical Biochemistry Standards of Laboratory Practice: Recommendations for the Use of Cardiac Markers in Coronary Artery Diseases Clin. Chem., July 1, 1999; 45(7): 1104 - 1121. [Abstract] [Full Text] [PDF] |
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