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Clinical Chemistry 44: 2004a-2005a, 1998;
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(Clinical Chemistry. 1998;44:2004-2005.)
© 1998 American Association for Clinical Chemistry, Inc.

Book Reviews

Element Analysis of Biological Samples. Principles and Practice.

K. Owen Ash

University of Utah, 500 Chipeta Way, Salt Lake City, UT 84108

Element Analysis of Biological Samples. Principles and Practice. G. Venkatesh Iyengar, K.S. Subramanian, and Joost R.W. Woittiez. Boca Raton, FL: CRC Press, 1998, 255 pp., $99.95. ISBN 0-8493-5424-2.

This well-documented monograph is recommended for laboratory analysts performing trace element analysis on biological specimens as well as for those who may be considering trace element analysis. The book is organized into eight chapters, of which six chapters deal with important issues before and after analysis. These issues include presampling, sampling and sample preparation, storage and preservation of biomedical specimens, sample decomposition and sample preparation methods for various instrumental techniques, and specimen banking and chemical analysis. The information in these chapters is well-documented and quite complete. However, readers must prioritize the issues and decide which of the many potential problem areas that have been reported in the literature are important in their own circumstances.

The concise historical review included in chapter one provides necessary background as the reader considers the emerging trends in bioanalytical chemistry treated in this chapter. Analysis of trace element species, one of the emerging trends, is the subject of chapter seven.

This book does not cover analytical methods or interpretation of results in detail. It will, however, serve as an excellent reference source for specimen selection and handling. Many problems can be avoided in element analysis of biological specimens when the importance of presampling and sample preparation and storage are understood by all who are involved in the process. This is an important reference book that will be used frequently in our laboratory.





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