Received on February 10, 2006
Accepted on June 13, 2006

Overview

Standards for Plasma and Serum Proteomics in Early Cancer Detection: A Needs Assessment Report from the National Institute of Standards and Technology-National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18-19, 2005

¹ NIST-National Cancer Institute Cancer Biomarker Reference Laboratory, Gaithersburg, MD
² Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD
³ Analytical Chemistry Division, NIST, Gaithersburg, MD
⁴ Center for Biomedical Proteomics and Center for Computational Medicine & Biology, University of Michigan, Ann Arbor, MI

^* To whom correspondence should be addressed. E-mail: peter.barker{at}nist.gov.

NIST and the National Cancer Institute cosponsored a workshop on August 18-19, 2005, to examine needs for reference materials for early cancer detection. This meeting focused on standards, methods, assays, reagents, and technologies. Needs for plasma and serum proteomics, DNA methylation, and specimen reference collections were discussed, and recommendations from participants were solicited. This report summarizes the discussion and recommendations for proteomics reference materials.