Editorials:

Roberta G. Reed

In Search of the Ideal Measure of High-Density Lipoprotein
Clin Chem 1997 43: 1809-1810. [Full Text] [PDF]  

John H. Eckfeldt and David E. Bruns

Another Step Toward Standardization of Methods for Measuring Hemoglobin A_1c
Clin Chem 1997 43: 1811-1813. [Full Text] [PDF]  

Reviews:

William N. Rezuke, Evelyn C. Abernathy, and Gregory J. Tsongalis

Molecular diagnosis of B- and T-cell lymphomas: fundamental principles and clinical applications
Clin Chem 1997 43: 1814-1823. [Abstract] [Full Text] [PDF]  

Point/Counterpoint:

Roger Ekins and Philip Edwards

Point On the meaning of "sensitivity"
Clin Chem 1997 43: 1824-1831. [Abstract] [Full Text] [PDF]  

Harry L. Pardue

Counterpoint The inseparable triad: analytical sensitivity, measurement uncertainty, and quantitative resolution
Clin Chem 1997 43: 1831-1837. [Abstract] [Full Text]  

Molecular Pathology and Genetics:

Stephen T. Wang, Sam Pizzolato, and Helen P. Demshar

Receiver operating characteristic plots to evaluate Guthrie, Wallac, and Isolab phenylalanine kit performance for newborn phenylketonuria screening
Clin Chem 1997 43: 1838-1842. [Abstract] [Full Text] [PDF]  

Xin Bai, Gregory Hosler, Beverly Barton Rogers, D. Brian Dawson, and Richard H. Scheuermann

Quantitative polymerase chain reaction for human herpesvirus diagnosis and measurement of Epstein–Barr virus burden in posttransplant lymphoproliferative disorder
Clin Chem 1997 43: 1843-1849. [Abstract] [Full Text] [PDF]  

Titus Hendrik Jan Huisman

Combinations of ß chain abnormal hemoglobins with each other or with ß-thalassemia determinants with known mutations: influence on phenotype
Clin Chem 1997 43: 1850-1856. [Abstract] [Full Text] [PDF]  

Lee-Jun C. Wong and Dinithi Senadheera

Direct detection of multiple point mutations in mitochondrial DNA
Clin Chem 1997 43: 1857-1861. [Abstract] [Full Text] [PDF]  

Test Utilization and Outcomes:

Ronald J. Elin, Michael W. Fried, Maureen Sampson, Mark Ruddel, David E. Kleiner, and Adrian M. DiBisceglie

Assessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis
Clin Chem 1997 43: 1952-1957. [Abstract] [Full Text] [PDF]  

Christa Cobbaert, Johannes C. Arentsen, Paul Mulder, Nicoline Hoogerbrugge, and Jan Lindemans

Significance of various parameters derived from biological variability of lipoprotein(a), homocysteine, cysteine, and total antioxidant status
Clin Chem 1997 43: 1958-1964. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Nosratollah Zarghami, Linda Grass, Edward R. Sauter, and Eleftherios P. Diamandis

Prostate-specific antigen in serum during the menstrual cycle
Clin Chem 1997 43: 1862-1867. [Abstract] [Full Text] [PDF]  

Ross W. Stephens, Anders N. Pedersen, Hans Jørgen Nielsen, Maria J. A. G. Hamers, Gunilla Høyer-Hansen, Ebbe Rønne, Esben Dybkjær, Keld Danø, and Nils Brünner

ELISA determination of soluble urokinase receptor in blood from healthy donors and cancer patients
Clin Chem 1997 43: 1868-1876. [Abstract] [Full Text] [PDF]  

Hannsjörg Baum, Siegmund Braun, Willie Gerhardt, Georges Gilson, Gerd Hafner, Margit Müller-Bardorff, Wolfgang Stein, Gerhard Klein, Christoph Ebert, Klaus Hallermayer, and Hugo A. Katus

Multicenter evaluation of a second-generation assay for cardiac troponin T
Clin Chem 1997 43: 1877-1884. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Mitsuyo Okazaki, Keiko Sasamoto, Toshio Muramatsu, and Seijin Hosaki

Evaluation of precipitation and direct methods for HDL-cholesterol assay by HPLC
Clin Chem 1997 43: 1885-1890. [Abstract] [Full Text] [PDF]  

Won-Ki Min, Jae Ok Lee, and Jung Won Huh

Relation between lipoprotein(a) concentrations in patients with acute-phase response and risk analysis for coronary heart disease
Clin Chem 1997 43: 1891-1895. [Abstract] [Full Text] [PDF]  

Ruediger Kock, Bert Delvoux, and Helmut Greiling

Determination of total cholesterol in serum by liquid chromatography–isotope dilution mass spectrometry
Clin Chem 1997 43: 1896-1903. [Abstract] [Full Text] [PDF]  

Peter G. Scheffer, Stephan J. L. Bakker, Robert J. Heine, and Tom Teerlink

Measurement of low-density lipoprotein particle size by high-performance gel-filtration chromatography
Clin Chem 1997 43: 1904-1912. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Jürgen Kropf, Josef O. Schurek, Antje Wollner, and Axel M. Gressner

Immunological measurement of transforming growth factor-beta 1 (TGF-ß1) in blood; assay development and comparison
Clin Chem 1997 43: 1965-1974. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Yoshitaka Morishita, Kiyoshi Nakane, Toshiaki Fukatsu, Nobuo Nakashima, Katsumi Tsuji, Yoshihiro Soya, Keizo Yoneda, Shigeki Asano, and Yoshihisa Kawamura

Kinetic assay of serum and urine for urea with use of urease and leucine dehydrogenase
Clin Chem 1997 43: 1932-1936. [Abstract] [Full Text] [PDF]  

Timo Lövgren, Pia Heinonen, Päivi Lehtinen, Harri Hakala, Johanna Heinola, Raimo Harju, Harri Takalo, Veli-Matti Mukkala, Ruth Schmid, Harri Lönnberg, Kim Pettersson, and Antti Iitiä

Sensitive bioaffinity assays with individual microparticles and time-resolved fluorometry
Clin Chem 1997 43: 1937-1943. [Abstract] [Full Text] [PDF]  

Uwe Kobold, Jan-Olof Jeppsson, Thomas Dülffer, Andreas Finke, Wieland Hoelzel, and Kor Miedema

Candidate reference methods for hemoglobin A_1c based on peptide mapping
Clin Chem 1997 43: 1944-1951. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Carole A. Cull, Susan E. Manley, Irene M. Stratton, H. Andrew W. Neil, Iain S. Ross, Rury R. Holman, Robert C. Turner, and David R. Matthews

Approach to maintaining comparability of biochemical data during long-term clinical trials
Clin Chem 1997 43: 1913-1918. [Abstract] [Full Text] [PDF]  

Johan Ellenius, Torgny Groth, Bertil Lindahl, and Lars Wallentin

Early assessment of patients with suspected acute myocardial infarction by biochemical monitoring and neural network analysis
Clin Chem 1997 43: 1919-1925. [Abstract] [Full Text] [PDF]  

Marta Stahl, Ivan Brandslund, Steffen Iversen, and Jens Anton Filtenborg

Quality assessment of blood glucose testing in general practitioners' offices improves quality
Clin Chem 1997 43: 1926-1931. [Abstract] [Full Text] [PDF]  

Immunology:

Johannes J. M. L. Hoffmann and Willy C. M. Janssen

HLA-B27 phenotyping with flow cytometry: further improvement by multiple monoclonal antibodies
Clin Chem 1997 43: 1975-1981. [Abstract] [Full Text] [PDF]  

Technical Briefs:

David W. Wilson, Helene N. Metz, L. Michael Graver, and Parinam S. Rao

Direct Method for Quantification of Free Malondialdehyde with High-Performance Capillary Electrophoresis in Biological Samples
Clin Chem 1997 43: 1982-1984. [Full Text] [PDF]  

Heike Baron, Steven Fung, Atakan Aydin, Sylvia Bähring, Eva Jeschke, Friedrich C. Luft, and Herbert Schuster

Oligonucleotide Ligation Assay for Detection of Apolipoprotein E Polymorphisms
Clin Chem 1997 43: 1984-1986. [Full Text]  

Barna Vásárhelyi, Teréz Szabó, Ágota Vér, and Tivadar Tulassay

Measurement of Na⁺/K⁺-ATPase Activity with an Automated Analyzer
Clin Chem 1997 43: 1986-1987. [Full Text]  

Richard A. Gniewek, Carla Sandbulte, and Philip C. Fox

Comparison of Antinuclear Antibody Testing Methods by ROC Analysis with Reference to Disease Diagnosis
Clin Chem 1997 43: 1987-1989. [Full Text]  

Pierre E. Wallemacq, Teresinha Leal, Tatiana Besse, Jean-Paul Squifflet, Raymond Reding, Jean-Bernard Otte, Jan Lerut, and Alexandre Hassoun

IMx Tacrolimus II vs IMx Tacrolimus Microparticle Enzyme Immunoassay Evaluated in Renal and Hepatic Transplant Patients
Clin Chem 1997 43: 1989-1991. [Full Text]  

Maria Isabel Covas, Luis Coca, Carmen Ricós, and Jaume Marrugat

Biological Variation of Superoxide Dismutase in Erythrocytes and Glutathione Peroxidase in Whole Blood,
Clin Chem 1997 43: 1991-1993. [Full Text]  

Takahiro Mitsui, Miharu Miyamura, Aritaka Matsunami, Kuniyuki Kitagawa, and Norio Arai

Measuring Nitrous Oxide in Exhaled Air by Gas Chromatography and Infrared Photoacoustic Spectrometry
Clin Chem 1997 43: 1993-1995. [Full Text]  

Michelle A. Miller, Giuseppe A. Sagnella, and Graham A. MacGregor

Extraction Method and Nonextracted Kit Method Compared for Measuring Plasma Aldosterone
Clin Chem 1997 43: 1995-1997. [Full Text]  

Claes Bergmark, M. Azam Mansoor, Asbjörn Svardal, and Ulf de Faire

Redox Status of Plasma Homocysteine and Related Aminothiols in Smoking and Nonsmoking Young Adults,
Clin Chem 1997 43: 1997-1999. [Full Text]  

Petr Husek

Urine Organic Acid Profiling by Capillary Gas Chromatography After a Simple Sample Pretreatment,
Clin Chem 1997 43: 1999-2001. [Full Text]  

Jens Pietzsch, Ulrich Julius, and Markolf Hanefeld

Rapid Determination of Total Homocysteine in Human Plasma by Using N(O,S)-Ethoxycarbonyl Ethyl Ester Derivatives and Gas Chromatography–Mass Spectrometry,
Clin Chem 1997 43: 2001-2004. [Full Text]  

Letters to the Editor:

Alan H. B. Wu, Yue-Jin Feng, Jeremy Nadelman, Matthew Acampora, and Paul N. Fiedler

Ectopic Production of Creatine Kinase MB: Updated Evaluation by Mass Assays
Clin Chem 1997 43: 2006-2007. [Full Text] [PDF]  

Frédéric Dumas, Pascal Eschwège, and Sylvain Loric

Acute Bacterial Prostatitis Induces Hematogenous Dissemination of Prostate Epithelial Cells
Clin Chem 1997 43: 2007-2008. [Full Text]  

Aino Eskola-Williams and Gary J. Fagan

Misleading Results with Opus® Magnum hLH Assay • A spokesman from Behring replies:
Clin Chem 1997 43: 2008-2010. [Full Text]  

Frank De Geeter

Parameters Relating to Ultrasensitive Prostate-Specific Antigen Assays
Clin Chem 1997 43: 2010-2011. [Full Text]  

George A. Smythe, Mark W. Duncan, J. Grassi, and P. Pradelles

Immunoassay of Catecholamines and Metabolites • Two of the authors of the article referred to reply:
Clin Chem 1997 43: 2011-2012. [Full Text]  

Toshio Okazaki, Tatsuo Nagai, Joris R. Delanghe, and Michel R. Langlois

Difference in Hemoglobin-Binding Ability of Polymers Among Haptoglobin Phenotypes • The authors of the article referred to respond:
Clin Chem 1997 43: 2012-2013. [Full Text]  

Book & Software Reviews:

A. Ralph Henderson

Evidence-Based Medicine—How to Practice and Teach EBM. D. L. Sackett, W. S. Richardson, W. Rosenberg, and R. B. Haynes. New York: Churchill Livingstone, 1997, 250 pp. Paperback, $24.99. ISBN 0-443-05686-2.
Clin Chem 1997 43: 2014. [Full Text] [PDF]  

Hassan M, E. Azzazy, and Robert H. Christenson

All About Albumin: Biochemistry, Genetics, and Medical Applications. Theodore Peters, Jr. San Diego, CA: Academic Press, 1996, 432 pp, $85.00. ISBN 0-12-552110-3
Clin Chem 1997 43: 2014-2015. [Full Text]  

Charles G. Durbin, Jr.

Acid Base Disorders—Computer-Aided Learning Software on CD-ROM. James Hooper, ed. London: Association of Clinical Biochemists, 1996, $72. ISBN 1-899938-00-1.
Clin Chem 1997 43: 2015. [Full Text]  

Correction:

Corrections
Clin Chem 1997 43: 2004-2005. [Full Text]  

The Clinical Chemist:

Complied by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 1997 43: 2016. [Full Text] [PDF]  

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