Editorials:

Raymond Gambino

C-Reactive Protein—Undervalued, Underutilized
Clin Chem 1997 43: 2017-2018. [Full Text] [PDF]  

Paul L. Wolf, Paul L. Wolf, George Liggins, and Dan Mercola

The Cloning Debates and Progress in Biotechnology
Clin Chem 1997 43: 2019-2020. [Full Text] [PDF]  

Reviews:

Yi-Wei Tang, Gary W. Procop, and David H. Persing

Molecular diagnostics of infectious diseases
Clin Chem 1997 43: 2021-2038. [Abstract] [Full Text] [PDF]  

Overall:

The San Diego Conference: Nucleic Acid Technology: The Cutting Edge of Discovery; November 6–8, 1997
Clin Chem 1997 43: 2213-2224. [Full Text] [PDF]  

Opinion:

Per Hyltoft Petersen, Dietmar Stöckl, Ole Blaabjerg, Bent Pedersen, Erling Birkemose, Linda Thienpont, Jens Flensted Lassen, and Jens Kjeldsen

Graphical interpretation of analytical data from comparison of a field method with a Reference Method by use of difference plots
Clin Chem 1997 43: 2039-2046. [Abstract] [Full Text] [PDF]  

Molecular Pathology and Genetics:

Donald H. Chace, Steven L. Hillman, Johan L. K. Van Hove, and Edwin W. Naylor

Rapid diagnosis of MCAD deficiency: quantitative analysis of octanoylcarnitine and other acylcarnitines in newborn blood spots by tandem mass spectrometry
Clin Chem 1997 43: 2106-2113. [Abstract] [Full Text] [PDF]  

Françoise Révillion, Louis Hornez, and Jean-Philippe Peyrat

Quantification of c-erbB-2 gene expression in breast cancer by competitive RT-PCR
Clin Chem 1997 43: 2114-2120. [Abstract] [Full Text] [PDF]  

Paola Carrera, Anna Maria Barbieri, Maurizio Ferrari, Pier Giorgio Righetti, Marilena Perego, and Cecilia Gelfi

Rapid detection of 21-hydroxylase deficiency mutations by allele-specific in vitro amplification and capillary zone electrophoresis
Clin Chem 1997 43: 2121-2127. [Abstract] [Full Text] [PDF]  

Test Utilization and Outcomes:

Jens Kjeldsen, Jens Flensted Lassen, Per Hyltoft Petersen, and Ivan Brandslund

Biological variation of International Normalized Ratio for prothrombin times, and consequences in monitoring oral anticoagulant therapy: computer simulation of serial measurements with goal-setting for analytical quality
Clin Chem 1997 43: 2175-2182. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Fred S. Apple, Alireza Falahati, Pamela R. Paulsen, Elizabeth A. Miller, and Scott W. Sharkey

Improved detection of minor ischemic myocardial injury with measurement of serum cardiac troponin I
Clin Chem 1997 43: 2047-2051. [Abstract] [Full Text] [PDF]  

Christopher P. Price, Thomas P. Milligan, and Claude Darte

Direct comparison of performance characteristics of two immunoassays for bone isoform of alkaline phosphatase in serum
Clin Chem 1997 43: 2052-2057. [Abstract] [Full Text] [PDF]  

J. Daniel Clemens, Michael V. Herrick, Frederick R. Singer, and David R. Eyre

Evidence that serum NTx (collagen-type I N-telopeptides) can act as an immunochemical marker of bone resorption
Clin Chem 1997 43: 2058-2063. [Abstract] [Full Text] [PDF]  

Bjarne Steen Dahler-Eriksen, Jens Flensted Lassen, Per Hyltoft Petersen, Erik Dalsgaard Lund, Torsten Lauritzen, and Ivan Brandslund

Evaluation of a near-patient test for C-reactive protein used in daily routine in primary healthcare by use of difference plots
Clin Chem 1997 43: 2064-2075. [Abstract] [Full Text] [PDF]  

Markus Karmatschek, Ina Maier, Markus J. Seibel, Henning W. Woitge, Reinhard Ziegler, and Franz P. Armbruster

Improved purification of human bone sialoprotein and development of a homologous radioimmunoassay
Clin Chem 1997 43: 2076-2082. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Patricia C. Fallest-Strobl, Elin Olafsdottir, Donald A. Wiebe, and James O. Westgard

Comparison of NCEP performance specifications for triglycerides, HDL-, and LDL-cholesterol with operating specifications based on NCEP clinical and analytical goals
Clin Chem 1997 43: 2164-2168. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Christiane Albrecht, Jürg Reichen, Jan Visser, Dirk K. F. Meijer, and Wolfgang Thormann

Differentiation between naproxen, naproxen–protein conjugates, and naproxen–lysine in plasma via micellar electrokinetic capillary chromatography—a new approach in the bioanalysis of drug targeting preparations
Clin Chem 1997 43: 2083-2090. [Abstract] [Full Text] [PDF]  

Sarah B. Coutts, Andrew T. Kicman, Derek T. Hurst, and David A. Cowan

Intramuscular administration of 5-dihydrotestosterone heptanoate: changes in urinary hormone profile
Clin Chem 1997 43: 2091-2098. [Abstract] [Full Text] [PDF]  

David M. Steinberg, Lori J. Sokoll, Kathy C. Bowles, James H. Nichols, Roger Roberts, Stephen K. Schultheis, and C. Michael O'Donnell

Clinical evaluation of Toxi · Prep^TM: a semiautomated solid-phase extraction system for screening of drugs in urine
Clin Chem 1997 43: 2099-2105. [Abstract] [Full Text] [PDF]  

Hematology:

Armando D'Angelo, Laura Galli, and Hartmut Lang on behalf of the IFCC Working Group Standardization of Coagulation Tests

Comparison of mean normal prothrombin time (PT) with PT of fresh normal pooled plasma or of a lyophilized control plasma (R82A) as denominator to express PT results: collaborative study of the International Federation of Clinical Chemistry
Clin Chem 1997 43: 2169-2174. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Juha Korhonen, Henrik Alfthan, Pekka Ylöstalo, Johannes Veldhuis, and Ulf-Håkan Stenman

Disappearance of human chorionic gonadotropin and its - and ß-subunits after term pregnancy
Clin Chem 1997 43: 2155-2163. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

C. Michael Hanbury, W. Greg Miller, and Robert B. Harris

Fiber-optic immunosensor for measurement of myoglobin
Clin Chem 1997 43: 2128-2136. [Abstract] [Full Text] [PDF]  

Nathalie Mario, Bruno Baudin, Christian Aussel, and Jacqueline Giboudeau

Capillary isoelectric focusing and high-performance cation-exchange chromatography compared for qualitative and quantitative analysis of hemoglobin variants
Clin Chem 1997 43: 2137-2142. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Richard Davey

Thyroxine, thyrotropin, and age in a euthyroid hospital patient population
Clin Chem 1997 43: 2143-2148. [Abstract] [Full Text] [PDF]  

Curtis A. Parvin and Ann M. Gronowski

Effect of analytical run length on quality-control (QC) performance and the QC planning process
Clin Chem 1997 43: 2149-2154. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Roger Johnson, Prudence McNutt, Stephen MacMahon, and Richard Robson

Use of the Friedewald Formula to Estimate LDL-Cholesterol in Patients with Chronic Renal Failure on Dialysis
Clin Chem 1997 43: 2183-2184. [Full Text] [PDF]  

Hayley J. Ridgway, Stephen O. Brennan, Andrew P. Fellowes, and Peter M. George

Rapid Detection of the Fibrinogen A16ArgHis Mutation
Clin Chem 1997 43: 2184-2186. [Full Text]  

Isabella Fermo, Cinzia Arcelloni, Erminia Casari, and Rita Paroni

Urine Pyridinium Cross-Links Determination by Beckman Cross Links Kit
Clin Chem 1997 43: 2186-2187. [Full Text]  

Elliot Plotkin, Jerome F. McAleer, M. Lucinda Cordeiro, Martin R. Ackland, Timothy M. Sheehan, and Robin A. Braithwaite

Convenient, Rapid Test for Lead in Blood with Use of Disposable Electrodes
Clin Chem 1997 43: 2187-2189. [Full Text]  

Paul J. Taylor, Nicholas S. Hogan, Stephen V. Lynch, Anthony G. Johnson, and Susan M. Pond

Improved Therapeutic Drug Monitoring of Tacrolimus (FK506) by Tandem Mass Spectrometry
Clin Chem 1997 43: 2189-2190. [Full Text]  

Hélène Blanché, Christel Valette, and Christine Bellanné-Chantelot

Optimization of Nonisotopic PCR–Single-Strand Conformation Polymorphism Analysis
Clin Chem 1997 43: 2190-2192. [Full Text]  

Mohammad A. Mansoor, Ole Kristensen, Tor Hervig, Per A. Drabløs, Jacob A. Stakkestad, Leik Woie, Oyvind Hetland, and Arve Osland

Low Concentrations of Folate in Serum and Erythrocytes of Smokers: Methionine Loading Decreases Folate Concentrations in Serum of Smokers and Nonsmokers
Clin Chem 1997 43: 2192-2194. [Full Text]  

Xiao-Hong Huang, Anne Salomäki, Riikka Malin, Timo Koivula, Hannu Jokela, and Terho Lehtimäki

Rapid Identification of Angiotensin-Converting Enzyme Genotypes by Capillary Electrophoresis
Clin Chem 1997 43: 2195-2196. [Full Text]  

Kyoko Inoue, Yasuyuki Suzuki, Shigehiro Yajima, Nobuyuki Shimozawa, Tadao Orii, and Naomi Kondo

Very Long Chain Fatty Acid Analysis of Dried Blood Spots on Filter Paper to Screen for Adrenoleukodystrophy
Clin Chem 1997 43: 2197-2198. [Full Text]  

Adalsteinn Gudmundsson, William B. Ershler, Brian Goodman, Stephanie J. Lent, Steven Barczi, and Molly Carnes

Serum Concentrations of Interleukin-6 Are Increased When Sampled Through an Indwelling Venous Catheter
Clin Chem 1997 43: 2199-2201. [Full Text]  

Abdul Kader and Hu Liu

Interference of Anthracycline Derivatives with Measurement of Proteins with BCA
Clin Chem 1997 43: 2201-2202. [Full Text]  

Kenneth R. Copeland, Bounthon Loun, and Frank A. Sedor

Stability of a Control Material Suitable for Quantitative Measurement of Urine Myoglobin
Clin Chem 1997 43: 2202-2204. [Full Text]  

Lucia Sacchetti, Claudia Sarrantonio, Lucio Pastore, Valeria Carlino, Giuseppe Calcagno, Anna Ferrajolo, and Francesco Salvatore

Rapid Identification of HLA DQA1*0501, DQB1*0201, and DRB1*04 Alleles in Celiac Disease by a PCR-Based Methodology
Clin Chem 1997 43: 2204-2206. [Full Text]  

Carmen Biosca, Carmen Ricós, Carlos Víctor Jiménez, Ricardo Lauzurica, and Román Galimany

Model for Establishing Biological Variation in Nonhealthy Situations: Renal Posttransplantation Data
Clin Chem 1997 43: 2206-2208. [Full Text]  

Nicole H. Jourdil, Philippe D. Fontanille, and Germain M. Bessard

Concurrent Determination of Second-Generation Antidepressants in Plasma by Using Gas Chromatography with Nitrogen–Phosphorus Detection
Clin Chem 1997 43: 2209-2210. [Full Text]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 1997 43: 2211-2212. [Full Text] [PDF]  

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