Editorials:

Charles Eby

Standardization of APTT Reagents for Heparin Therapy Monitoring: Urgent or Fading Priority?
Clin Chem 1997 43: 1105-1107. [Extract] [Full Text] [PDF]  

Gregg B. Fields

Mass-Spectrometric Approaches for DNA-Based Genetic Screening
Clin Chem 1997 43: 1108-1109. [Extract] [Full Text] [PDF]  

David A. Cowan and Andrew T. Kicman

Doping in Sport: Misuse, Analytical Tests, and Legal Aspects
Clin Chem 1997 43: 1110-1113. [Extract] [Full Text] [PDF]  

Reviews:

Peter Nollau and Christoph Wagener

Methods for detection of point mutations: performance and quality assessment
Clin Chem 1997 43: 1114-1128. [Abstract] [Full Text] [PDF]  

Molecular Pathology:

Mohamed S. Rashed, Martin P. Bucknall, Douglas Little, Amin Awad, Minnie Jacob, Mohamed Alamoudi, Mona Alwattar, and Pinar T. Ozand

Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated flagging of abnormal profiles
Clin Chem 1997 43: 1129-1141. [Abstract] [Full Text] [PDF]  

Pia Heinonen, Antti Iitiä, Toni Torresani, and Timo Lövgren

Simple triple-label detection of seven cystic fibrosis mutations by time-resolved fluorometry
Clin Chem 1997 43: 1142-1150. [Abstract] [Full Text] [PDF]  

Andreas Braun, Daniel P. Little, and Hubert Köster

Detecting CFTR gene mutations by using primer oligo base extension and mass spectrometry
Clin Chem 1997 43: 1151-1158. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Kenichi Tamate, Margaret Charleton, James P. Gosling, Declan Egan, Mutsuo Ishikawa, Patrick F. Fottrell, and Marian M. Kane

Direct colorimetric monoclonal antibody enzyme immunoassay for estradiol-17ß in saliva
Clin Chem 1997 43: 1159-1164. [Abstract] [Full Text] [PDF]  

François Dancoine, Gisèle Couplet, Jacques Buvat, Catherine Guittard, Gérard Marcolin, and Jean-Claude Fourlinnie

Analytical and clinical evaluation of the Immulite^® estradiol assay in serum from patients undergoing in vitro fertilization: estradiol increase in mature follicles
Clin Chem 1997 43: 1165-1171. [Abstract] [Full Text] [PDF]  

Chuanliang Liu and Larry D. Bowers

Mass spectrometric characterization of nicked fragments of the ß-subunit of human chorionic gonadotropin
Clin Chem 1997 43: 1172-1181. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Abdulaziz H. Alzeer, Mohsen A. F. El-Hazmi, Arjumand S. Warsy, Ziauddin A. Ansari, and Mohammed S. Yrkendi

Serum enzymes in heat stroke: prognostic implication
Clin Chem 1997 43: 1182-1187. [Abstract] [Full Text] [PDF]  

Koji Takada, Hidekazu Nasu, Nozomu Hibi, Yutaka Tsukada, Toshiaki Shibasaki, Kiyotaka Fujise, Masahiro Fujimuro, Hitoshi Sawada, Hideyoshi Yokosawa, and Kiyoshi Ohkawa

Serum concentrations of free ubiquitin and multiubiquitin chains
Clin Chem 1997 43: 1188-1195. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Cristine A. Costa, Gilmar C. Trivelato, Adriana M. P. Pinto, and Etelvino J. H. Bechara

Correlation between plasma 5-aminolevulinic acid concentrations and indicators of oxidative stress in lead-exposed workers
Clin Chem 1997 43: 1196-1202. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

David L. Woodrum, Chester M. French, Timothy M. Hill, Steven J. Roman, Harold L. Slatore, Jennifer L. Shaffer, Lisa G. York, Kathy L. Eure, Kathleen G. Loveland, Gail H. Gasior, Paula C. Southwick, and L. Blair Shamel

Analytical performance of the Tandem^®-R free PSA immunoassay measuring free prostate-specific antigen
Clin Chem 1997 43: 1203-1208. [Abstract] [Full Text] [PDF]  

Test Utilization and Outcomes:

Flemming Nielsen, Bo Borg Mikkelsen, Jesper Bo Nielsen, Helle Raun Andersen, and Philippe Grandjean

Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors
Clin Chem 1997 43: 1209-1214. [Abstract] [Full Text] [PDF]  

Hematology:

Anton M. H. P. van den Besselaar, Jacoline Neuteboom, Joyce Meeuwisse-Braun, and Rogier M. Bertina

Preparation of lyophilized partial thromboplastin time reagent composed of synthetic phospholipids: usefulness for monitoring heparin therapy
Clin Chem 1997 43: 1215-1222. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Jorge Joven, Xavier Clivillé, Jordi Camps, Eugenia Espinel, Jose Simó, Elisabet Vilella, and Angel Oliver

Plasma protein abnormalities in nephrotic syndrome: effect on plasma colloid osmotic pressure and viscosity
Clin Chem 1997 43: 1223-1231. [Abstract] [Full Text] [PDF]  

History:

David A. H. Roethel

Some historical perspectives on AACC
Clin Chem 1997 43: 1232-1235. [Extract] [Full Text] [PDF]  

Technical Briefs:

Michael Kaplan, Chava Leiter, Cathy Hammerman, and Bernard Rudensky

Comparison of Commercial Screening Tests for Glucose-6-Phosphate Dehydrogenase Deficiency in the Neonatal Period
Clin Chem 1997 43: 1236-1237. [Extract] [Full Text] [PDF]  

Teresinha Leal, Philippe Dupret, Alexandre Hassoun, and Pierre E. Wallemacq

Topical Application of Eosin to Burns Produces Interference in Measurement of Serum Vancomycin by Fluorescence Polarization Immunoassay
Clin Chem 1997 43: 1238-1240. [Extract] [Full Text]  

John Colford, Dawn Sailer, and Craig Langman

Five Osteocalcin Assays Compared: Tracer Specificity, Fragment Interference, and Calibration
Clin Chem 1997 43: 1240-1241. [Extract] [Full Text]  

Lee-Jun C. Wong and Ching-Wan Lam

Alternative, Noninvasive Tissues for Quantitative Screening of Mutant Mitochondrial DNA
Clin Chem 1997 43: 1241-1243. [Extract] [Full Text]  

Joop H. A. Roding, Ton Weterings, and Cees van der Heiden

Plasma Renin Activity: Temperature Optimum at ~45 °C
Clin Chem 1997 43: 1243-1244. [Extract] [Full Text]  

Letters to the Editor:

Henning Mørland and Anne Smith-Kielland

Urine Screening for Flunitrazepam: Applicability of Emit® Immunoassay
Clin Chem 1997 43: 1245-1246. [Extract] [Full Text] [PDF]  

Sohji Nagase, Norio Ohkoshi, Atsushi Ueda, Kazumasa Aoyagi, and Akio Koyama

Hydrogen Peroxide Interferes with Detection of Nitric Oxide by an Electrochemical Method
Clin Chem 1997 43: 1246. [Extract] [Full Text]  

H. T. Delves and Karl Verebey

Blood Lead Screening (Continued) • Dr. Verebey responds:
Clin Chem 1997 43: 1246-1248. [Extract] [Full Text]  

Perrine Hoet and Dominique Lison

A Nonoccupational Source of Mercury Intoxication
Clin Chem 1997 43: 1248. [Extract] [Full Text]  

Leonard Mori, Susan Waldhuber, Tom Metcalfe, and Jürgen Rauh

Salicylate Interference with the Roche Cobas Integra Chloride Electrode • Spokespersons for Roche Diagnostics respond:
Clin Chem 1997 43: 1249-1250. [Extract] [Full Text]  

Yat-Sun Leung, Kenneth Dees, Richard Cyr, Ione Schloegel, and Pai C. Kao

Falsely Increased Serum Estradiol Results Reported in Direct Estradiol Assays
Clin Chem 1997 43: 1250-1251. [Extract] [Full Text]  

Stephen T. Wang, Sam Pizzolato, Helen P. Demshar, and Lesbia F. Smith

Decline in Blood Lead in Ontario Children Correlated to Decreasing Consumption of Leaded Gasoline, 1983–1992
Clin Chem 1997 43: 1251-1252. [Extract] [Full Text]  

Book Reviews:

Charles A. Bradley

Life, the Lab, and Everything. Ian Wilkinson. Washington, DC: AACC Press, 1996. 178 pp. Soft cover, $19.95. ISBN 0-915274-85-X.
Clin Chem 1997 43: 1253. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor
Clin Chem 1997 43: 1254-1260. [Extract] [Full Text] [PDF]  

Doping in Sport Symposium Proceedings:

Doping in Sport and Society: Misuse, Analytical Tests and Legal Aspects Proceedings of a scientific colloquium held on July 11, 1996, as part of the XVI International Congress of Clinical Chemistry, July 7–12, 1996, Wembley, London, UK
Clin Chem 1997 43: 1261. [Extract] [Full Text] [PDF]  

Werner W. Franke and Brigitte Berendonk

Hormonal doping and androgenization of athletes: a secret program of the German Democratic Republic government
Clin Chem 1997 43: 1262-1279. [Abstract] [Full Text] [PDF]  

Don H. Catlin, Caroline K. Hatton, and Sanja H. Starcevic

Issues in detecting abuse of xenobiotic anabolic steroids and testosterone by analysis of athletes' urine
Clin Chem 1997 43: 1280-1288. [Abstract] [Full Text] [PDF]  

F. C. W. Wu

Endocrine aspects of anabolic steroids
Clin Chem 1997 43: 1289-1292. [Abstract] [Full Text] [PDF]  

Ulf-Håkan Stenman, Leila Unkila-Kallio, Juha Korhonen, and Henrik Alfthan

Immunoprocedures for detecting human chorionic gonadotropin: clinical aspects and doping control
Clin Chem 1997 43: 1293-1298. [Abstract] [Full Text] [PDF]  

Larry D. Bowers

Analytical advances in detection of performance-enhancing compounds
Clin Chem 1997 43: 1299-1304. [Abstract] [Full Text] [PDF]  

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