Editorials:

Barry S. Skikne

Circulating Transferrin Receptor Assay—Coming of Age
Clin Chem 1998 44: 7-9. [Extract] [Full Text] [PDF]  

Mendel Tuchman

Molecular Diagnosis of Medium-Chain Acyl-CoA Dehydrogenase Deficiency by Oligonucleotide Ligation Assay
Clin Chem 1998 44: 10-11. [Extract] [Full Text] [PDF]  

Special Reports:

Michael Neumaier, Andreas Braun, Christoph Wagener, and Biology Techniques

Fundamentals of quality assessment of molecular amplification methods in clinical diagnostics
Clin Chem 1998 44: 12-26. [Abstract] [Full Text] [PDF]  

Hematology:

Jonathan Ben-Ezra, Linda Bork, and Richard A. McPherson

Evaluation of the Sysmex UF-100 automated urinalysis analyzer
Clin Chem 1998 44: 92-95. [Abstract] [Full Text] [PDF]  

Chiu Wah Tsang, Ross Lazarus, Wayne Smith, Paul Mitchell, Jerry Koutts, and Leslie Burnett

Hematological indices in an older population sample: derivation of healthy reference values
Clin Chem 1998 44: 96-101. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Martin Straume, Michael L. Johnson, and Johannes D. Veldhuis

Statistically accurate estimation of hormone concentrations and associated uncertainties: methodology, validation, and applications
Clin Chem 1998 44: 116-123. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Xinrong Zhang, Rita Cornelis, Jurgen De Kimpe, Louis Mees, and Norbert Lameire

Study of arsenic–protein binding in serum of patients on continuous ambulatory peritoneal dialysis
Clin Chem 1998 44: 141-147. [Abstract] [Full Text] [PDF]  

Molecular Pathology and Genetics:

Nahed El Kassar, Gilles Hetet, Jean Brière, and Bernard Grandchamp

X-Chromosome inactivation in healthy females: incidence of excessive lyonization with age and comparison of assays involving DNA methylation and transcript polymorphisms
Clin Chem 1998 44: 61-67. [Abstract] [Full Text] [PDF]  

Eeva-Liisa Romppanen, Tarja Mononen, and Ilkka Mononen

Molecular diagnosis of medium-chain acyl-CoA dehydrogenase deficiency by oligonucleotide ligation assay
Clin Chem 1998 44: 68-71. [Abstract] [Full Text] [PDF]  

Katerina Angelopoulou, Michael A. Levesque, Dionyssios Katsaros, Rob Shipman, and Eleftherios P. Diamandis

Exon 5 of the p53 gene is a target for deletions in ovarian cancer
Clin Chem 1998 44: 72-77. [Abstract] [Full Text] [PDF]  

Test Utilization and Outcomes:

Robert Clarke, Peter Woodhouse, Arve Ulvik, Chris Frost, Paul Sherliker, Helga Refsum, Per M. Ueland, and Kay-Tee Khaw

Variability and determinants of total homocysteine concentrations in plasma in an elderly population
Clin Chem 1998 44: 102-107. [Abstract] [Full Text] [PDF]  

Harvey B. Lipman and J. Rex Astles

Quantifying the bias associated with use of discrepant analysis
Clin Chem 1998 44: 108-115. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Torsten Arndt, Rolf Hackler, Tilman O. Kleine, and Axel M. Gressner

Validation by isoelectric focusing of the anion-exchange isotransferrin fractionation step involved in determination of carbohydrate-deficient transferrin by the CDTect assay
Clin Chem 1998 44: 27-34. [Abstract] [Full Text] [PDF]  

Jean Allen, Kristin R. Backstrom, Jeffrey A. Cooper, MaryAnne C. Cooper, Thomas C. Detwiler, David W. Essex, Rose P. Fritz, Robert T. Means, Jr., Peter B. Meier, Samuel R. Pearlman, Beatrice Roitman-Johnson, and Paul A. Seligman

Measurement of soluble transferrin receptor in serum of healthy adults
Clin Chem 1998 44: 35-39. [Abstract] [Full Text] [PDF]  

Hlosukwazi Khumalo, Zvenyika A. R. Gomo, Victor M. Moyo, Victor R. Gordeuk, Thokozile Saungweme, Tracey A. Rouault, and Innocent T. Gangaidzo

Serum transferrin receptors are decreased in the presence of iron overload
Clin Chem 1998 44: 40-44. [Abstract] [Full Text] [PDF]  

Alan E. Mast, Morey A. Blinder, Ann M. Gronowski, Cara Chumley, and Mitchell G. Scott

Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations
Clin Chem 1998 44: 45-51. [Abstract] [Full Text] [PDF]  

Robert H. Christenson, Fred S. Apple, David L. Morgan, Gladys L. Alonsozana, Kristin Mascotti, Marilyn Olson, Robert T. McCormack, Frank H. Wians, Jr., Joseph H. Keffer, and Show-Hong Duh

Cardiac troponin I measurement with the ACCESS^® immunoassay system: analytical and clinical performance characteristics
Clin Chem 1998 44: 52-60. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Maria Stella Graziani, Luisa Zanolla, Gabriella Righetti, Cristina Marchetti, Paolo Mocarelli, and Santica M. Marcovina

Plasma apolipoproteins A-I and B in survivors of myocardial infarction and in a control group
Clin Chem 1998 44: 134-140. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Gilles Kertesz, Béatrice Bourcier, Hélène Cailla, and Frédéric Jean

Immunoradiometric assay of succinylated corticotropin: an improved method for quantification of ACTH
Clin Chem 1998 44: 78-85. [Abstract] [Full Text] [PDF]  

David H. Wilson, William Groskopf, Stephen Hsu, Diane Caplan, Tom Langner, Michael Baumann, Deborah DeManno, Gregg Williams, Don Payette, Cheryl Dagel, Don Lynch, and George Manderino

Rapid, automated assay for progesterone on the Abbott AxSYM(TM) analyzer
Clin Chem 1998 44: 86-91. [Abstract] [Full Text] [PDF]  

Laboratory Management:

A. Ralph Henderson, Suba Krishnan, Sharon Webb, C. Mark Cheung, Darius J. Nazir, and Harold Richardson

Proficiency testing of creatine kinase and creatine kinase-2: the experience of the Ontario Laboratory Proficiency Testing Program
Clin Chem 1998 44: 124-133. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Dogan Yücel, Sinan Aydogdu, Sengül Çehreli, Gülsevim Saydam, Hayrettin Canatan, Mehmet Senes, Birsen Çigdem Topkaya, and Serpil Nebioglu

Increased oxidative stress in dilated cardiomyopathic heart failure
Clin Chem 1998 44: 148-154. [Abstract] [Full Text] [PDF]  

Brad S. Karon, Thomas M. Daly, and Mitchell G. Scott

Mechanisms of dopamine and dobutamine interference in biochemical tests that use peroxide and peroxidase to generate chromophore
Clin Chem 1998 44: 155-160. [Abstract] [Full Text] [PDF]  

Michael M. Millner, Wolfgang Franthal, Gabriela H. Thalhammer, Andrea Berghold, Reingard M. Aigner, Gerhard F. Füger, and Gilbert Reibnegger

Neopterin concentrations in cerebrospinal fluid and serum as an aid in differentiating central nervous system and peripheral infections in children
Clin Chem 1998 44: 161-167. [Abstract] [Full Text] [PDF]  

Case Conference:

Anne F. Eder, Cindy M. McGrath, Yvonne G. Dowdy, John E. Tomaszewski, Frances M. Rosenberg, Robert B. Wilson, Bryan A. Wolf, and Leslie M. Shaw

Ethylene glycol poisoning: toxicokinetic and analytical factors affecting laboratory diagnosis
Clin Chem 1998 44: 168-177. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Kleopatra H. Schulpis, George A. Karikas, and George Kokotos

Direct Molecular Interaction of Phenylalanine with DNA Measured by Reversed-Phase HPLC
Clin Chem 1998 44: 178-179. [Extract] [Full Text] [PDF]  

Oliver Hasselwander, Dorothy McMaster, Damian G. Fogarty, A. Peter Maxwell, D. Paul Nicholls, and Ian S. Young

Serum Paraoxonase and Platelet-Activating Factor Acetylhydrolase in Chronic Renal Failure
Clin Chem 1998 44: 179-181. [Extract] [Full Text] [PDF]  

Ferdinando Mannello, Leone Condemi, Antonella Cardinali, Giuseppe Bianchi, and Giancarlo Gazzanelli

High Concentrations of Prostate-Specific Antigen in Urine of Women Receiving Oral Contraceptives
Clin Chem 1998 44: 181-183. [Extract] [Full Text] [PDF]  

Sandra D. O'Dell, Darren J. Wilson, Paul N. Durrington, Steve E. Humphries, and Ian N. M. Day

CpG-PCR Combined with Sample Pooling and Mutant Enrichment for CpG Mutation Screening in Population Studies
Clin Chem 1998 44: 183-185. [Extract] [Full Text] [PDF]  

Book Reviews:

James B. Smart

Principles and Practices of Immunoassays, 2nd ed. Christopher Price and David Newman. New York: Stockton Press, 1997, 750 pp. $140.00. ISBN 1–56159-175–0.
Clin Chem 1998 44: 194. [Extract] [Full Text] [PDF]  

Letters to the Editor:

John A. Martin and Kathryn Brownbill

When Is an Indole Not an Indole?
Clin Chem 1998 44: 186. [Extract] [Full Text] [PDF]  

Anne M. Molloy, James L. Mills, Peadar N. Kirke, Alexander S. Whitehead, Donald G. Weir, and John M. Scott

Whole-Blood Folate Values in Subjects with Different Methylenetetrahydrofolate Reductase Genotypes: Differences Between the Radioassay and Microbiological Assays
Clin Chem 1998 44: 186-188. [Extract] [Full Text] [PDF]  

David E. C. Cole, Denis C. Lehotay, and Jovan Evrovski

Simplified Simultaneous Assay of Total Plasma Homocysteine and Methionine by HPLC and Pulsed Integrated Amperometry
Clin Chem 1998 44: 188-190. [Extract] [Full Text] [PDF]  

Gary C. Mockli

The Sia Euglobulin Precipitation Test Revisited
Clin Chem 1998 44: 190. [Extract] [Full Text] [PDF]  

Prakash C. Tewari, Julie S. Williams, Amy B. Blase, and Roger L. Sokoloff

Analytical Characteristics of Seminal Fluid PSA Differ from Those of Serum PSA
Clin Chem 1998 44: 191-193. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

The Clinical Chemist
Clin Chem 1998 44: 195-196. [Extract] [Full Text] [PDF]  

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