Editorials:

Y. M. Dennis Lo

Quantitative Assays for Telomerase: Means for Studying the End
Clin Chem 1998 44: 2399-2400. [Full Text] [PDF]  

Harvey L. Levy

Newborn Screening by Tandem Mass Spectrometry: A New Era
Clin Chem 1998 44: 2401-2402. [Full Text] [PDF]  

Eric Vilain

CYPs, SNPs, and Molecular Diagnosis in the Postgenomic Era
Clin Chem 1998 44: 2403-2404. [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Donald H. Chace, John E. Sherwin, Steven L. Hillman, Fred Lorey, and George C. Cunningham

Use of phenylalanine-to-tyrosine ratio determined by tandem mass spectrometry to improve newborn screening for phenylketonuria of early discharge specimens collected in the first 24 hours
Clin Chem 1998 44: 2405-2409. [Abstract] [Full Text] [PDF]  

Anthony A. Killeen, Renée R. Jiddou, and Kumud S. Sane

Characterization of frequent polymorphisms in intron 2 of CYP21: application to analysis of segregation of CYP21 alleles
Clin Chem 1998 44: 2410-2415. [Abstract] [Full Text] [PDF]  

Cristina Dassi, Stefano Signorini, Piermario Gerthoux, Mariangela Cazzaniga, and Paolo Brambilla

Cytochrome P450 1B1 mRNA measured in blood mononuclear cells by quantitative reverse transcription-PCR
Clin Chem 1998 44: 2416-2421. [Abstract] [Full Text] [PDF]  

André Klein, Alexandra Lebreton, Jérome Lemoine, Jean-Marc Périni, Philippe Roussel, and Jean-Claude Michalski

Identification of urinary oligosaccharides by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
Clin Chem 1998 44: 2422-2428. [Abstract] [Full Text] [PDF]  

Christian Datz, Thomas Haas, Heinrich Rinner, Friedrich Sandhofer, Wolfgang Patsch, and Bernhard Paulweber

Heterozygosity for the C282Y mutation in the hemochromatosis gene is associated with increased serum iron, transferrin saturation, and hemoglobin in young women: a protective role against iron deficiency?
Clin Chem 1998 44: 2429-2432. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Aleksei G. Katrukha, Anastasia V. Bereznikova, Vladimir L. Filatov, Tatiana V. Esakova, Olga V. Kolosova, Kim Pettersson, Timo Lövgren, Tamara V. Bulargina, Igor R. Trifonov, Nikolai A. Gratsiansky, Kari Pulkki, Liisa-Maria Voipio-Pulkki, and Nikolai B. Gusev

Degradation of cardiac troponin I: implication for reliable immunodetection
Clin Chem 1998 44: 2433-2440. [Abstract] [Full Text] [PDF]  

Tomomi Yajima, Atsuhito Yagihashi, Hidekazu Kameshima, Daisuke Kobayashi, Daisuke Furuya, Koichi Hirata, and Naoki Watanabe

Quantitative reverse transcription-PCR assay of the RNA component of human telomerase using the TaqMan fluorogenic detection system
Clin Chem 1998 44: 2441-2445. [Abstract] [Full Text] [PDF]  

Minoru Hirose, Junko Abe-Hashimoto, Hidetoshi Tahara, Toshihide Ide, and Tadashi Yoshimura

New method to measure telomerase activity by transcription-mediated amplification and hybridization protection assay
Clin Chem 1998 44: 2446-2452. [Abstract] [Full Text] [PDF]  

Takashi Murakami, Shozo Kusachi, Masahiro Murakami, Issei Sano, Tadahisa Uesugi, Masaaki Murakami, Ryouichi Hirami, Akio Kajiyama, Jun Kondo, and Takao Tsuji

Time-dependent changes of serum carboxy-terminal peptide of type I procollagen and carboxy-terminal telopeptide of type I collagen concentrations in patients with acute myocardial infarction after successful reperfusion: correlation with left ventricular volume indices
Clin Chem 1998 44: 2453-2461. [Abstract] [Full Text] [PDF]  

Massimo Gion, Riccardo Mione, Paola Barioli, Mario Barichello, Filiberto Zattoni, Tommaso Prayer-Galetti, Mario Plebani, Giuseppe Aimo, Carlo Terrone, Fabio Manferrari, Giuseppe Madeddu, Livio Caberlotto, Andrea Fandella, Carlo Pianon, and Luisa Vianello

Percent free prostate-specific antigen in assessing the probability of prostate cancer under optimal analytical conditions
Clin Chem 1998 44: 2462-2470. [Abstract] [Full Text] [PDF] Correction  

Wan-Ming Zhang, Patrik Finne, Jari Leinonen, Satu Vesalainen, Stig Nordling, Sakari Rannikko, and Ulf-Hakan Stenman

Characterization and immunological determination of the complex between prostate-specific antigen and ₂-macroglobulin
Clin Chem 1998 44: 2471-2479. [Abstract] [Full Text] [PDF]  

John B. Whitfield, Linda M. Fletcher, Theresa L. Murphy, Lawrie W. Powell, June Halliday, Andrew C. Heath, and Nicholas G. Martin

Smoking, obesity, and hypertension alter the dose–response curve and test sensitivity of carbohydrate-deficient transferrin as a marker of alcohol intake
Clin Chem 1998 44: 2480-2489. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Elizabeth Teng Leary, Tao Wang, Daniel J. Baker, Donald D. Cilla, Jianhua Zhong, G. Russell Warnick, Katsuyuki Nakajima, and Richard J. Havel

Evaluation of an immunoseparation method for quantitative measurement of remnant-like particle-cholesterol in serum and plasma
Clin Chem 1998 44: 2490-2498. [Abstract] [Full Text] [PDF]  

Maria-Luisa Arranz-Peña, Juan Tasende-Mata, and Francisco J. Martin-Gil

Comparison of two homogeneous assays with a precipitation method and an ultracentrifugation method for the measurement of HDL-cholesterol
Clin Chem 1998 44: 2499-2505. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Wai-Kai Lai, Chi-Pui Pang, Lap-Kay Law, Raymond Wong, Chi-Kong Li, and Patrick Man-Pan Yuen

Routine analysis of plasma busulfan by gas chromatography–mass fragmentography
Clin Chem 1998 44: 2506-2510. [Abstract] [Full Text] [PDF]  

Thierry Dervieux and Roselyne Boulieu

Identification of 6-methylmercaptopurine derivative formed during acid hydrolysis of thiopurine nucleotides in erythrocytes, using liquid chromatography–mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance assay
Clin Chem 1998 44: 2511-2515. [Abstract] [Full Text] [PDF]  

Victor W. Armstrong, Ekkehard Schuetz, Qingling Zhang, Stephan Groothuisen, Christa Scholz, Maria Shipkova, Hoda Aboleneen, and Michael Oellerich

Modified pentamer formation assay for measurement of tacrolimus and its active metabolites: comparison with liquid chromatography–tandem mass spectrometry and microparticle enzyme-linked immunoassay (MEIA-II)
Clin Chem 1998 44: 2516-2523. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Markus Meyer, Franz P. Armbruster, Ina Maier, Jens Schwing, Christlieb Haller, Albert Missbichler, Knut Adermann, Wolf-Georg Forssmann, and Wolfgang Woloszczuk

Urinary and plasma urodilatin measured by a direct RIA using a highly specific antiserum
Clin Chem 1998 44: 2524-2529. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Huub E. van Ingen, Daniel W. Chan, Walter Hubl, Hayato Miyachi, Rafael Molina, Lutz Pitzel, Alvaro Ruibal, Jean C. Rymer, and Ingrid Domke

Analytical and clinical evaluation of an electrochemiluminescence immunoassay for the determination of CA 125
Clin Chem 1998 44: 2530-2536. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Esa Leppänen and Benoit Dugué

When to collect blood specimens: midmorning vs fasting samples
Clin Chem 1998 44: 2537-2542. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Päivi K. Ylikangas and Ilkka T. Mononen

Glycosylasparaginase as a Marker Enzyme in the Detection of I-Cell Disease
Clin Chem 1998 44: 2543-2544. [Full Text] [PDF]  

Fabrice Lefèvre, Grégoire Moutel, Frédérique Carré-Pigeon, Jean Caron, and Philippe Gillery

Automated Nephelometric Assay for Seminal Fluid Transferrin
Clin Chem 1998 44: 2544-2546. [Full Text] [PDF]  

Karl J. Lackner and Gerd Schmitz

ß-VLDL of Patients with Type III Hyperlipoproteinemia Interferes with Homogeneous Determination of HDL-Cholesterol Based on Polyethylene Glycol-modified Enzymes
Clin Chem 1998 44: 2546-2548. [Full Text] [PDF]  

Carlo Bellini, Wanda Bonacci, Enrico Parodi, and Giovanni Serra

Serum -Fetoprotein in Newborns
Clin Chem 1998 44: 2548-2550. [Full Text] [PDF]  

Robert C. Hawkins

Furosemide Interference in Newer Free Thyroxine Assays
Clin Chem 1998 44: 2550-2551. [Full Text] [PDF]  

Cathy Hammerman, Robert Goldstein, Michael Kaplan, Maya Eran, Doris Goldschmidt, Arthur I. Eidelman, and Lawrence M. Gartner

Bilirubin in the Premature: Toxic Waste or Natural Defense?
Clin Chem 1998 44: 2551-2553. [Full Text] [PDF]  

Letters to the Editor:

Robert E. Wenk

Mechanism of Interference by Hemolysis in Immunoassays and Requirements for Sample Quality
Clin Chem 1998 44: 2554. [Full Text] [PDF]  

Kayoko Shimoharada, Sumiko Inoue, Mutsuko Nakahara, Naoto Kanzaki, Shuji Shimizu, Dongchon Kang, Naotaka Hamasaki, and Sachiko Kinoshita

Urine Concentration of Biopyrrins: A New Marker for Oxidative Stress in Vivo
Clin Chem 1998 44: 2554-2555. [Full Text] [PDF]  

Tim M. Reynolds

Vitamin B₆ Deficiency May Also Be Important
Clin Chem 1998 44: 2555-2556. [Full Text] [PDF]  

Janko Kos, Borut Stabuc, Nina Cimerman, and Nils Brünner

Serum Cystatin C, a New Marker of Glomerular Filtration Rate, Is Increased during Malignant Progression
Clin Chem 1998 44: 2556-2557. [Full Text] [PDF]  

Rémy Sapin, Michèle d'Herbomez, Jean Louis Schlienger, and Jean Louis Wemeau

Anti-Thyrotropin Antibody Interference in Thyrotropin Assays
Clin Chem 1998 44: 2557-2559. [Full Text] [PDF]  

Mauro Panteghini and Franca Pagani

Evaluation of Two Automated Immunoassays for Measurement of Free Deoxypyridinoline in Urine Using Analytical Goals Derived from Biological Variation
Clin Chem 1998 44: 2559. [Full Text] [PDF]  

Book Reviews:

Valerio M. Genta

Clinical Investigation and Statistics in Laboratory Medicine. Richard G. Jones and R. Bryan Payne. London: ACB Venture Publications, 1997, 193 pp, $38.00, ISBN 0902429-21-3.
Clin Chem 1998 44: 2560. [Full Text] [PDF]  

Invited Reviewers 1998:

Invited Reviewers—1998
Clin Chem 1998 44: 2561-2563. [Full Text] [PDF]  

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