Editorials:

Roland Valdes, Jr. and Saeed A. Jortani

Monitoring of Unbound Digoxin in Patients Treated with Anti-Digoxin Antigen-binding Fragments: A Model for the Future?
Clin Chem 1998 44: 1883-1885. [Extract] [Full Text] [PDF]  

Opinion:

Anthony J. A. Wright, Paul M. Finglas, and Susan Southon

Erythrocyte folate analysis: a cause for concern?
Clin Chem 1998 44: 1886-1891. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Ulrich Gross, Shigeru Sassa, Karl Jacob, Jean-Charles Deybach, Yves Nordmann, Margareta Frank, and Manfred O. Doss

5-Aminolevulinic acid dehydratase deficiency porphyria: a twenty-year clinical and biochemical follow-up
Clin Chem 1998 44: 1892-1896. [Abstract] [Full Text] [PDF]  

Christa Bräutigam, Ron A. Wevers, Riet J. T. Jansen, Jan A. M. Smeitink, Johanneke F. de Rijk-van Andel, Fons J. M. Gabreëls, and Georg F. Hoffmann

Biochemical hallmarks of tyrosine hydroxylase deficiency
Clin Chem 1998 44: 1897-1904. [Abstract] [Full Text] [PDF]  

Antonia García, Coral Barbas, Rosa Aguilar, and Mario Castro

Capillary electrophoresis for rapid profiling of organic acidurias
Clin Chem 1998 44: 1905-1911. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Jürgen Bleier, Karl-Paul Vorderwinkler, Jürgen Falkensammer, Peter Mair, Otto Dapunt, Bernd Puschendorf, and Johannes Mair

Different intracellular compartmentations of cardiac troponins and myosin heavy chains: a causal connection to their different early release after myocardial damage
Clin Chem 1998 44: 1912-1918. [Abstract] [Full Text] [PDF]  

Vincent Ricchiuti, Ellen M. Voss, Arthur Ney, Mark Odland, Page A. W. Anderson, and Fred S. Apple

Cardiac troponin T isoforms expressed in renal diseased skeletal muscle will not cause false-positive results by the second generation cardiac troponin T assay by Boehringer Mannheim
Clin Chem 1998 44: 1919-1924. [Abstract] [Full Text] [PDF]  

Christopher Heeschen, Britta U. Goldmann, Robert. H. Moeller, and Christian W. Hamm

Analytical performance and clinical application of a new rapid bedside assay for the detection of serum cardiac troponin I
Clin Chem 1998 44: 1925-1930. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

P. Barton Duell, David L. Wheaton, Amy Shultz, and Hien Nguyen

Inhibition of LDL oxidation by melatonin requires supraphysiologic concentrations
Clin Chem 1998 44: 1931-1936. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Maurice D. Laryea, Folkert Steinhagen, Sandra Pawliczek, and Udo Wendel

Simple method for the routine determination of betaine and N,N-dimethylglycine in blood and urine
Clin Chem 1998 44: 1937-1941. [Abstract] [Full Text] [PDF]  

Jan L. Cogill, Paul J. Taylor, Ian S. Westley, Raymond G. Morris, Stephen V. Lynch, and Anthony G. Johnson

Evaluation of the tacrolimus II microparticle enzyme immunoassay (MEIA II) in liver and renal transplant recipients
Clin Chem 1998 44: 1942-1946. [Abstract] [Full Text] [PDF]  

Idris T. Ocal and Terrence R. Green

Serum digoxin in the presence of Digibind: determination of digoxin by the Abbott AxSYM and Baxter Stratus II immunoassays by direct analysis without pretreatment of serum samples
Clin Chem 1998 44: 1947-1950. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Karen P. Peterson, James G. Pavlovich, David Goldstein, Randie Little, Jack England, and Charles M. Peterson

What is hemoglobin A1c? An analysis of glycated hemoglobins by electrospray ionization mass spectrometry
Clin Chem 1998 44: 1951-1958. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Jerry Dechert and Kenneth E. Case

Multivariate approach to quality control in clinical chemistry
Clin Chem 1998 44: 1959-1963. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Birgitta Näslund, Lars Ståhle, Arne Lundin, Björn Anderstam, Peter Arner, and Jonas Bergström

Luminometric single step urea assay using ATP-hydrolyzing urease
Clin Chem 1998 44: 1964-1973. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Mario Plebani, Daniela Bernardi, Daniela Basso, Franco Borghesan, and Diego Faggian

Measurement of specific immunoglobulin E: intermethod comparison and standardization
Clin Chem 1998 44: 1974-1979. [Abstract] [Full Text] [PDF]  

Case Reports:

Jean-François Benoist, Daniel Orbach, and Daniel Biou

False increase in C-reactive protein attributable to heterophilic antibodies in two renal transplant patients treated with rabbit antilymphocyte globulin
Clin Chem 1998 44: 1980-1985. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Jürgen Geisel, Tanja Walz, Marion Bodis, Sabine Quast, and Wolfgang Herrmann

Fluorescence-based SSCP Analysis with Automatic Allele Detection Demonstrated for the Factor V Leiden Mutation
Clin Chem 1998 44: 1986-1987. [Extract] [Full Text] [PDF]  

Anne Berit Guttormsen, Per Magne Ueland, Per Eystein Lønning, Olav Mella, and Helga Refsum

Kinetics of Plasma Total Homocysteine in Patients Receiving High-Dose Methotrexate Therapy
Clin Chem 1998 44: 1987-1989. [Extract] [Full Text] [PDF]  

Steven P. Siembieda and David J. Lakatua

Improved Method to Retrieve DNA from Dried Silver-stained Polyacrylamide Gels
Clin Chem 1998 44: 1989-1991. [Extract] [Full Text] [PDF]  

Ferdinando Mannello, Francesca Luchetti, Domenico Lancioli, Serafina Battistelli, Stefano Papa, and Giancarlo Gazzanelli

Prostate-specific Antigen Expression in Neoplastic Human Myeloid Cell Lines
Clin Chem 1998 44: 1991-1993. [Extract] [Full Text] [PDF]  

Osamu Takamiya and Shigeru Takeuchi

Dysfunctional Factor VII Variant (FVII Tondabayashi) with R79Q: Determination of Mutated Site with Monoclonal Anti-Human Factor VII Antibody (B101/B1)
Clin Chem 1998 44: 1993-1995. [Extract] [Full Text] [PDF]  

Marie-Hélène Schlageter, Jérôme Larghero, Bruno Cassinat, Marie-Elisabeth Toubert, Caroline Borschneck, and Jean-Didier Rain

Serum Carcinoembryonic Antigen, Cancer Antigen 125, Cancer Antigen 15-3, Squamous Cell Carcinoma, and Tumor-associated Trypsin Inhibitor Concentrations during Healthy Pregnancy
Clin Chem 1998 44: 1995-1998. [Extract] [Full Text] [PDF]  

Letters to the Editor:

John G. Lewis and Peter A. Elder

Alternative ELISA for Sex Hormone-Binding Globulin in Plasma
Clin Chem 1998 44: 1999. [Extract] [Full Text] [PDF]  

Wolfgang J. Schnedl, Rainer W. Lipp, Martin Trinker, and Pierre Hopmeier

Hemoglobin D [ß 121(GH4)GluGln] Causing Falsely Low and High HbA_1c Values in HPLC
Clin Chem 1998 44: 1999-2000. [Extract] [Full Text]  

Ralph Fingerhut

Determination of Cerebrospinal Fluid Glucose with the Vitros DT60 II Dry Chemistry System
Clin Chem 1998 44: 2000-2001. [Extract] [Full Text] [PDF]  

Laurence A. Cole, T. James Abbott, and E. Glenn Armstrong

Comment on the Nature and Specificity of Bayer Corporation and Chiron Diagnostics hCG Immunoassays
Clin Chem 1998 44: 2001-2002. [Extract] [Full Text] [PDF]  

Ruggero Dittadi, Danila Coradini, Sabrina Meo, Ester Pirronello, Maria Grazia Daidone, and Massimo Gion

Tissue Polypeptide Antigen as a Putative Indicator of Apoptosis
Clin Chem 1998 44: 2002-2003. [Extract] [Full Text] [PDF]  

Book Reviews:

Pauline Y. Lau

Clinical Laboratory Management.
Clin Chem 1998 44: 2004. [Extract] [Full Text] [PDF]  

K. Owen Ash

Element Analysis of Biological Samples. Principles and Practice.
Clin Chem 1998 44: 2004-2005. [Extract] [Full Text]  

Jessica K. Booker

Clinical Applications of PCR (Methods in Molecular Medicine, Volume 16).
Clin Chem 1998 44: 2005. [Extract] [Full Text] [PDF]  

Laurence M. Demers

Endocrine and Metabolic Testing Manual, Third Edition.
Clin Chem 1998 44: 2005. [Extract] [Full Text]  

Oak Ridge Conference 1998:

Katie M. Smith

Introduction
Clin Chem 1998 44: 2006-2007. [Extract] [Full Text] [PDF]  

Oak Ridge Conference:

Larry J. Kricka

Miniaturization of analytical systems
Clin Chem 1998 44: 2008-2014. [Abstract] [Full Text] [PDF]  

Roger P. Ekins

Ligand assays: from electrophoresis to miniaturized microarrays
Clin Chem 1998 44: 2015-2030. [Abstract] [Full Text] [PDF]  

Rachel M. Ostroff, Diana Maul, Gregory R. Bogart, Shao Yang, Jennifer Christian, Deborah Hopkins, David Clark, Brian Trotter, and Garret Moddel

Fixed polarizer ellipsometry for simple and sensitive detection of thin films generated by specific molecular interactions: applications in immunoassays and DNA sequence detection
Clin Chem 1998 44: 2031-2035. [Abstract] [Full Text] [PDF]  

John W. Silzel, Bibijana Cercek, Charles Dodson, Tsong Tsay, and Robert J. Obremski

Mass-sensing, multianalyte microarray immunoassay with imaging detection
Clin Chem 1998 44: 2036-2043. [Abstract] [Full Text] [PDF]  

Oak Ridge Poster Sessions:

Frederick Van Lente and Vito Gatautis

Cost-efficient Use of Gas Chromatography–Mass Spectrometry: A "Piggyback" Method for Analysis of Gabapentin
Clin Chem 1998 44: 2044-2045. [Extract] [Full Text] [PDF]  

Steven J. Zoha, Shakuntala Ramnarain, and F. C. Thomas Allnutt

Ultrasensitive Direct Fluorescent Immunoassay for Thyroid Stimulating Hormone
Clin Chem 1998 44: 2045-2046. [Extract] [Full Text] [PDF]  

Brian H. Erickson, Bernard J. Van Wie, Dan M. Leatzow, Guihua Liu, Philip C. Thayer, and Thomas O. Tiffany

Charge Coupled Device Optics System for Simultaneous Measurement of Multiple Reactions in a Microplate
Clin Chem 1998 44: 2046-2049. [Extract] [Full Text] [PDF]  

Clare E. Hodgson and Ronald Pethig

Determination of the Viability of Escherichia coli at the Single Organism Level by Electrorotation
Clin Chem 1998 44: 2049-2051. [Extract] [Full Text] [PDF]  

Joel M. Blatt, Michael P. Allen, Sunitha Baddam, Badri N. Dasu, David M. Dickens, Stephen J. Hardt, Raymond T. Hebert, Ya-Chen Hsu, Chris T. Kitazawa, Sheng-Fen Li, Wilma M. Mangan, Paul J. Patel, James W. Pfeiffer, Nol B. Quiwa, Mark A. Scratch, and Joseph T. Widunas

A Miniaturized, Self-contained, Single-use, Disposable Assay Device for the Quantitative Determination of the Bone Resorption Marker, NTx, in Urine
Clin Chem 1998 44: 2051-2052. [Extract] [Full Text] [PDF]  

Michael J. Benecky, Kevin L. McKinney, Kimberly M. Peterson, and John Q. Kamerud

Simultaneous Detection of Multiple Analytes Using Copalis Technology: A Reduction to Practice
Clin Chem 1998 44: 2052-2054. [Extract] [Full Text] [PDF]  

Perry L. Smith, Cindy R. WalkerPeach, R. Jerrold Fulton, and Dwight B. DuBois

A Rapid, Sensitive, Multiplexed Assay for Detection of Viral Nucleic Acids Using the FlowMetrix System
Clin Chem 1998 44: 2054-2056. [Extract] [Full Text] [PDF]  

C. Albertson, C. Davis, J. Ellison, and C. Chu

Clinical Evaluation of a New, Miniaturized Biosensor for Self-monitoring of Blood Glucose
Clin Chem 1998 44: 2056-2057. [Extract] [Full Text] [PDF]  

Kerry G. Oliver, John R. Kettman, and R. Jerrold Fulton

Multiplexed Analysis of Human Cytokines by Use of the FlowMetrix System
Clin Chem 1998 44: 2057-2060. [Extract] [Full Text] [PDF]  

Peter R. Levison, Jon W. Dennis, Kevin D. Jones, Richard W. Philpott, Susan L. Taylor, and Volker Grimm

New Approaches in the Binding of DNA for Clinical Applications
Clin Chem 1998 44: 2060-2061. [Extract] [Full Text] [PDF]  

Michael Lynch, Anne Thompson, Bruce Gaumond, John Kilroy, Holly Leonard, Ann Jacob, and Thomas Jackson

Transference of Reference Intervals in the Validation of Automated Chemiluminescent Immunoassays on a New Platform
Clin Chem 1998 44: 2061-2063. [Extract] [Full Text] [PDF]  

Priscilla K Zia, Nasrin Namei, Ashok Patel, Kris J. Kontis, Narayan Nayak, Roy Chen, and Thomas M. Li

Fully Automated Enzyme Immunoassay System for the Determination of Activator-specific Histamine Release from Basophils in Whole Blood
Clin Chem 1998 44: 2063-2065. [Extract] [Full Text] [PDF]  

Hashem Akhavan-Tafti, Lekkala V. Reddy, Sarada Siripurapu, Barry A. Schoenfelner, Richard S. Handley, and A. Paul Schaap

Chemiluminescent Detection of DNA in Low- and Medium-Density Arrays
Clin Chem 1998 44: 2065-2066. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

The Clinical Chemist
Clin Chem 1998 44: 2067-2070. [Extract] [Full Text] [PDF]  

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