Editorials:

Michael W. Varner

Ceruloplasmin and Preterm Premature Rupture of the Membranes
Clin Chem 1999 45: 1887-1888. [Full Text] [PDF]  

Special Reports:

Thomas Roberts, Mathew Smith, and Barry Roberts

Observations on Centrifugation: Application to Centrifuge Development
Clin Chem 1999 45: 1889-1897. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Henrik Ørum, Mogens H. Jakobsen, Troels Koch, Jens Vuust, and Martin B. Borre

Detection of the Factor V Leiden Mutation by Direct Allele-specific Hybridization of PCR Amplicons to Photoimmobilized Locked Nucleic Acids
Clin Chem 1999 45: 1898-1905. [Abstract] [Full Text] [PDF]  

Nicole J. Munro, Karen Snow, Jeffrey A. Kant, and James P. Landers

Molecular Diagnostics on Microfabricated Electrophoretic Devices: From Slab Gel- to Capillary- to Microchip-based Assays for T- and B-Cell Lymphoproliferative Disorders
Clin Chem 1999 45: 1906-1917. [Abstract] [Full Text] [PDF]  

Claudia Casini Raggi, Maria Letizia Bagnoni, Gian Paolo Tonini, Mario Maggi, Giovanna Vona, Pamela Pinzani, Katia Mazzocco, Bruno De Bernardi, Mario Pazzagli, and Claudio Orlando

Real-Time Quantitative PCR for the Measurement of MYCN Amplification in Human Neuroblastoma with the TaqMan Detection System
Clin Chem 1999 45: 1918-1924. [Abstract] [Full Text] [PDF]  

Karl R. Klingler, Thomas Junold, and Klaus Wielckens

Activated Protein C Resistance: Automated Detection of the Factor V Leiden Mutation by Mismatch Hybridization
Clin Chem 1999 45: 1925-1931. [Abstract] [Full Text] [PDF]  

Andreas Nitsche, Nina Steuer, Christian Andreas Schmidt, Olfert Landt, and Wolfgang Siegert

Different Real-Time PCR Formats Compared for the Quantitative Detection of Human Cytomegalovirus DNA
Clin Chem 1999 45: 1932-1937. [Abstract] [Full Text] [PDF]  

Yu-Hung Chen, Wei-Chang Wang, Kung-Chia Young, Ting-Tsung Chang, and Shu-Hui Chen

Plastic Microchip Electrophoresis for Analysis of PCR Products of Hepatitis C Virus
Clin Chem 1999 45: 1938-1943. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Marta Sánchez-Carbayo, Antonia Espasa, Virtudes Chinchilla, Enrique Herrero, Julián Megías, Antonio Mira, and Federico Soria

New Electrochemiluminescent Immunoassay for the Determination of CYFRA 21-1: Analytical Evaluation and Clinical Diagnostic Performance in Urine Samples of Patients with Bladder Cancer
Clin Chem 1999 45: 1944-1953. [Abstract] [Full Text] [PDF]  

Norman H.L. Chiu and Theodore K. Christopoulos

Two-Site Expression Immunoassay Using a Firefly Luciferase-coding DNA Label
Clin Chem 1999 45: 1954-1959. [Abstract] [Full Text] [PDF]  

Angeliki Magklara, Andreas Scorilas, William J. Catalona, and Eleftherios P. Diamandis

The Combination of Human Glandular Kallikrein and Free Prostate-specific Antigen (PSA) Enhances Discrimination Between Prostate Cancer and Benign Prostatic Hyperplasia in Patients with Moderately Increased Total PSA
Clin Chem 1999 45: 1960-1966. [Abstract] [Full Text] [PDF]  

Nader Rifai, Rana Joubran, Harry Yu, Mohamad Asmi, and Mohidien Jouma

Inflammatory Markers in Men with Angiographically Documented Coronary Heart Disease
Clin Chem 1999 45: 1967-1973. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Akira Kondo, Yoshinori Muranaka, Isao Ohta, and Takashi Kanno

Dynamic Reaction in a Homogeneous HDL-Cholesterol Assay Visualized by Electron Microscopy
Clin Chem 1999 45: 1974-1980. [Abstract] [Full Text] [PDF]  

Tao Wang, Katsuyuki Nakajima, Elizabeth Teng Leary, G. Russ Warnick, Jeffrey S. Cohn, Paul N. Hopkins, Lily L. Wu, Donald D. Cilla, Jianhua Zhong, and Richard J. Havel

Ratio of Remnant-like Particle-Cholesterol to Serum Total Triglycerides Is an Effective Alternative to Ultracentrifugal and Electrophoretic Methods in the Diagnosis of Familial Type III Hyperlipoproteinemia
Clin Chem 1999 45: 1981-1987. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Jörg Feldmann, Vivian W-M. Lai, William R. Cullen, Mingsheng Ma, Xiufen Lu, and X. Chris Le

Sample Preparation and Storage Can Change Arsenic Speciation in Human Urine
Clin Chem 1999 45: 1988-1997. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Christian Murr, Anton Bergant, Martin Widschwendter, Kurt Heim, Hans Schröcksnadel, and Dietmar Fuchs

Neopterin Is an Independent Prognostic Variable in Females with Breast Cancer
Clin Chem 1999 45: 1998-2004. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Tomoyasu Higashimoto, Shoji Yano, Masamichi Ito, Noreen C. Clark-Sheehan, Linda Cowan, and Richard G. Boles

Rapid Detection of FGFR Mutations in Syndromic Craniosynostosis by Temporal Temperature Gradient Gel Electrophoresis
Clin Chem 1999 45: 2005-2006. [Full Text] [PDF]  

Nicola Bizzaro, Paola Pasini, and Bruno Finco

False-Positive Reactions for IgA Anti-Phospholipid and Anti-ß₂-Glycoprotein I Antibodies in Patients with IgA Monoclonal Gammopathy
Clin Chem 1999 45: 2007-2010. [Full Text] [PDF]  

Ingvar Rydén, Arne Lundblad, and Peter Påhlsson

Lectin ELISA for Analysis of ₁-Acid Glycoprotein Fucosylation in the Acute Phase Response
Clin Chem 1999 45: 2010-2012. [Full Text] [PDF]  

Maximilian Ledochowski, Florian Überall, Theresia Propst, and Dietmar Fuchs

Fructose Malabsorption Is Associated with Lower Plasma Folic Acid Concentrations in Middle-Aged Subjects
Clin Chem 1999 45: 2013-2014. [Full Text] [PDF]  

Jacques Rohayem, Karsten Conrad, Thomas Zimmermann, and Karl-Heinz Frank

Comparison of the Diagnostic Accuracy of Three Commercially Available Enzyme Immunoassays for Anti-p53 Antibodies
Clin Chem 1999 45: 2014-2016. [Full Text] [PDF]  

Jean-Frédéric Salazar, Bernard Herbeth, Gérard Siest, and Pierre Leroy

Stability of Blood Homocysteine and Other Thiols: EDTA or Acidic Citrate?
Clin Chem 1999 45: 2016-2019. [Full Text] [PDF]  

Mitsuharu Ogino, Shuichi Hiyamuta, Akihiko Kadota, Yuko Io, and Makoto Hanazono

Active Ceruloplasmin in Cervicovaginal Secretions: Its Association with Term Premature Rupture of the Membranes
Clin Chem 1999 45: 2019-2022. [Full Text] [PDF]  

Eeva-Liisa Romppanen and Ilkka Mononen

PCR-Oligonucleotide Ligation Assay from Dried Blood Spots
Clin Chem 1999 45: 2022-2025. [Full Text] [PDF]  

Lene Christiansen, Anette Bygum, Kristian Thomsen, Fleming Brandrup, Mogens Hørder, and Niels E. Petersen

Denaturing Gradient Gel Electrophoresis Analysis of the Hemochromatosis (HFE) Gene: Impact of HFE Gene Mutations on the Manifestation of Porphyria Cutanea Tarda
Clin Chem 1999 45: 2025-2026. [Full Text] [PDF]  

Cecília Martínez-Brú, Cristina Gómez, Mariano Cortés, Germán Soriano, Carlos Guarner, Teresa Planella, and Francesc González-Sastre

Ascitic Fluid Interleukin-8 to Distinguish Spontaneous Bacterial Peritonitis and Sterile Ascites in Cirrhotic Patients
Clin Chem 1999 45: 2027-2028. [Full Text] [PDF]  

Miguel de la Hoya, Eduardo Díaz-Rubio, and Trinidad Caldés

Denaturing Gradient Gel Electrophoresis-based Analysis of Loss of Heterozygosity Distinguishes Nonobvious, Deleterious BRCA1 Variants from Nonpathogenic Polymorphisms
Clin Chem 1999 45: 2028-2030. [Full Text] [PDF]  

Margitta Neufeld, Ulrike Nowak-Göttl, and Ralf Junker

Citrate-Theophylline-Adenine-Dipyridamol Buffer Is Preferable to Citrate Buffer as an Anticoagulant for Flow Cytometric Measurement of Platelet Activation
Clin Chem 1999 45: 2030-2033. [Full Text] [PDF]  

Nelson L.S. Tang, Tse N. Leung, Jun Zhang, Tze K. Lau, and Y.M. Dennis Lo

Detection of Fetal-derived Paternally Inherited X-Chromosome Polymorphisms in Maternal Plasma
Clin Chem 1999 45: 2033-2035. [Full Text] [PDF]  

David Smail, Leah Gambino, Christopher Boles, and Georgirene D. Vladutiu

Rapid, Cost-effective Gene Mutation Screening for Carnitine Palmitoyltransferase II Deficiency Using Whole Blood on Filter Paper
Clin Chem 1999 45: 2035-2038. [Full Text] [PDF]  

Letters to the Editor:

Robert Granouillet, Françoise Rascle, Christine Bonneau, Annette Chamson, Jacques Frey, and Christian Perier

Evidence of Temperature-dependent Interference in an Immunonephelometric Assay by Monoclonal IgM
Clin Chem 1999 45: 2039-2040. [Full Text] [PDF]  

Bernard L. Croal, Ian Mitchell, Arthur Dickie, Patrica A. Duff, Nicholas P. Cohen, Iain S. Ross, Klaus Jung, Brigitte Brux, Pranav Sinha, Michael Lein, Dietmar Schnorr, and Stefan A. Loening

Complexed Prostate-specific Antigen and the "Prostate-specific Antigen Gap" • The authors of the Technical Brief cited above reply:
Clin Chem 1999 45: 2040-2041. [Full Text] [PDF]  

Susan M. Koethe, John Zielinski, and Billy W. Perry

Glycohemoglobin Results in Samples with C or S Trait Measured on the Bio-Rad Diamat and Variant Express
Clin Chem 1999 45: 2041. [Full Text] [PDF]  

Stephen J. Frost, Stanley S. Levinson, and Irina V. Kaplan

More on Heterophile and Human Anti-Animal Antibodies • The authors of the article cited above reply:
Clin Chem 1999 45: 2042-2043. [Full Text]  

Book Reviews:

Edgard Delvin

Handbook of Diagnostic Endocrinology. Ishwarlal Jialal, William E. Winter, and Daniel W. Chan, eds. Washington, DC: AACC Press, 1999, 250 pp., $36.00. ISBN 1-890883-08-5.
Clin Chem 1999 45: 2044. [Full Text] [PDF]  

Ira A. Shulman

Transfusion Therapy: Clinical Principles and Practice. Paul D. Mintz, ed., Bethesda, MD: AABB Press, 1999, 481 pp., $119.00. ISBN 1-56395-099-5
Clin Chem 1999 45: 2044-2045. [Full Text]  

Corrections:

Correction
Clin Chem 1999 45: 2045-2044. [Full Text]  

Correction:

Correction
Clin Chem 1999 45: 2045-2044. [Full Text] [PDF]  

Correction
Clin Chem 1997 45: 2046. [Full Text] [PDF]  

1999 San Diego Conference:

The San Diego Conference Nucleic Acid Technologies in Disease Detection November 17–19, 1999
Clin Chem 1999 45: 2047-2053. [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 1999 45: 2054. [Full Text] [PDF]  

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