Editorials:

Timothy J. O'Leary

Reducing the Impact of Endogenous Ribonucleases on Reverse Transcription-PCR Assay Systems
Clin Chem 1999 45: 449-450. [Full Text] [PDF]  

Wolfgang Holzgreve and Sinuhe Hahn

Novel Molecular Biological Approaches for the Diagnosis of Preeclampsia
Clin Chem 1999 45: 451-452. [Full Text] [PDF]  

Reviews:

Larry J. Kricka

Nucleic Acid Detection Technologies — Labels, Strategies, and Formats
Clin Chem 1999 45: 453-458. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Sytske H. Moolenaar, Jo Poggi-Bach, Udo F.H. Engelke, Jacqueline M.B. Corstiaensen, Arend Heerschap, Jan G.N. de Jong, Barbara A. Binzak, Jerry Vockley, and Ron A. Wevers

Defect in Dimethylglycine Dehydrogenase, a New Inborn Error of Metabolism: NMR Spectroscopy Study
Clin Chem 1999 45: 459-464. [Abstract] [Full Text] [PDF]  

Mauri M. Hämäläinen, Jarkko U. Eskola, Jukka Hellman, and Kari Pulkki

Major Interference from Leukocytes in Reverse Transcription-PCR Identified as Neurotoxin Ribonuclease from Eosinophils: Detection of Residual Chronic Myelogenous Leukemia from Cell Lysates by Use of an Eosinophil-depleted Cell Preparation
Clin Chem 1999 45: 465-471. [Abstract] [Full Text] [PDF]  

Test Utilization and Outcomes:

Lothar Thomas, Herbert Leyh, Michael Marberger, Emilio Bombardieri, Pierfrancesco Bassi, Francesco Pagano, Vito Pansadoro, Cora N. Sternberg, Laurent Boccon-Gibod, Vincent Ravery, Dominique Le Guludec, Alain Meulemans, Pierre Conort, and Laura Ishak

Multicenter Trial of the Quantitative BTA TRAK Assay in the Detection of Bladder Cancer
Clin Chem 1999 45: 472-477. [Abstract] [Full Text] [PDF]  

Bjarne Steen Dahler-Eriksen, Torsten Lauritzen, Jens Flensted Lassen, Erik D. Lund, and Ivan Brandslund

Near-Patient Test for C-Reactive Protein in General Practice: Assessment of Clinical, Organizational, and Economic Outcomes
Clin Chem 1999 45: 478-485. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Hiroshi Nagasaki, Motoyuki Watanabe, Naoki Komatsu, Takashi Kaneko, Jean Y. Dubé, Tadahiro Kajita, Yoshihiro Saitoh, and Yohsuke Ohta

Epitope Analysis of a Prostate-specific Antigen (PSA) C-Terminal-specific Monoclonal Antibody and New Aspects for the Discrepancy between Equimolar and Skewed PSA Assays
Clin Chem 1999 45: 486-496. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Kazuyoshi Yamauchi, Minoru Tozuka, Tetsuo Nakabayashi, Mitsutoshi Sugano, Hiroya Hidaka, Yoshiyuki Kondo, and Tsutomu Katsuyama

Apolipoprotein E in Cerebrospinal Fluid: Relation to Phenotype and Plasma Apolipoprotein E Concentrations
Clin Chem 1999 45: 497-504. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Christiane Oddoze, Jean Christophe Dubus, Monique Badier, Xavier Thirion, Anne Marie Pauli, Jean Pastor, and Bernard Bruguerolle

Urinary Cotinine and Exposure to Parental Smoking in a Population of Children with Asthma
Clin Chem 1999 45: 505-509. [Abstract] [Full Text] [PDF]  

Buddha D. Paul, Eric T. Shimomura, and Michael L. Smith

A Practical Approach to Determine Cutoff Concentrations for Opiate Testing with Simultaneous Detection of Codeine, Morphine, and 6-Acetylmorphine in Urine
Clin Chem 1999 45: 510-519. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Nicos D. Christofides, Ewan Wilkinson, Mary Stoddart, David C. Ray, and Geoff J. Beckett

Assessment of Serum Thyroxine Binding Capacity-dependent Biases in Free Thyroxine Assays
Clin Chem 1999 45: 520-525. [Abstract] [Full Text] [PDF]  

John W. Colford, Bruce A. Lueddecke, Michael Salvati, Dave Hanna, Dawn Sailer, Sundeep Khosla, B. Lawrence Riggs, and Craig B. Langman

Immunoradiometric Assay for Intact Human Osteocalcin(1–49) without Cross-Reactivity to Breakdown Products
Clin Chem 1999 45: 526-531. [Abstract] [Full Text] [PDF]  

Ray K. Iles, Mohammed K. Javid, Lionel K. Gunn, and Tim Chard

Cross-Reaction with Luteinizing Hormone ß-Core Is Responsible for the Age-dependent Increase of Immunoreactive ß-Core Fragment of Human Chorionic Gonadotropin in Women with Nonmalignant Conditions
Clin Chem 1999 45: 532-538. [Abstract] [Full Text] [PDF]  

Ron A. Wevers, Udo F.H. Engelke, Sytske H. Moolenaar, Christa Bräutigam, Jan G.N. de Jong, Ries Duran, Ronney A. de Abreu, and Albert H. van Gennip

¹H-NMR Spectroscopy of Body Fluids: Inborn Errors of Purine and Pyrimidine Metabolism
Clin Chem 1999 45: 539-548. [Abstract] [Full Text] [PDF]  

Tine Børglum Jensen, Linda Hilsted, and Jens F. Rehfeld

Library of Sequence-specific Radioimmunoassays for Human Chromogranin A
Clin Chem 1999 45: 549-560. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Adji Widjaja, Richard J. Morris, Jonathan C. Levy, Keith N. Frayn, Susan E. Manley, and Robert C. Turner

Within- and Between-Subject Variation in Commonly Measured Anthropometric and Biochemical Variables
Clin Chem 1999 45: 561-566. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Friedrich Priem, Harald Althaus, Maria Birnbaum, Pranav Sinha, Harald S. Conradt, and Klaus Jung

ß-Trace Protein in Serum: A New Marker of Glomerular Filtration Rate in the Creatinine-Blind Range
Clin Chem 1999 45: 567-568. [Full Text] [PDF]  

Ludvig N.W. Daae and Trine Andreassen

Chronic Lymphocytic Leukemia Cells May Interfere in a Glycated Hemoglobin Assay Based on Fluorescence Quenching
Clin Chem 1999 45: 569. [Full Text] [PDF]  

Aila Leino

Fully Automated Measurement of Total Homocysteine in Plasma and Serum on the Abbott IMx Analyzer
Clin Chem 1999 45: 569-570. [Full Text] [PDF]  

Mendel Tuchman and Mark T. McCann

Phenylalanine and Tyrosine Quantification by Stable Isotope Dilution Liquid Chromatography–Mass Spectrometry from Filter Paper Blood Spots
Clin Chem 1999 45: 571-572. [Full Text] [PDF]  

John P. Beilby, Alex W. Prins, and Nigel R. Swanson

Determination of Hepatic Iron Concentration in Fresh and Paraffin-embedded Tissue
Clin Chem 1999 45: 573. [Full Text] [PDF]  

Guohua Cao and Ronald L. Prior

Anthocyanins Are Detected in Human Plasma after Oral Administration of an Elderberry Extract
Clin Chem 1999 45: 574-576. [Full Text] [PDF]  

Karine Marangon, Sridevi Devaraj, and Ishwarlal Jialal

Measurement of Protein Carbonyls in Plasma of Smokers and in Oxidized LDL by an ELISA
Clin Chem 1999 45: 577. [Full Text] [PDF]  

Sharon Saw, Sunil Sethi, and Tar-Choon Aw

Technical Evaluation of Thyroid Assays on the Vitros ECi
Clin Chem 1999 45: 578-580. [Full Text] [PDF]  

Letters to the Editor:

Jaak Billen, Zahur Zaman, Georges Claeys, and Norbert Blanckaert

Limited Dynamic Range of a New Assay for Serum Folate
Clin Chem 1999 45: 581. [Full Text] [PDF]  

Stephen Manzella, Ann Gronowski, Jack Ladenson, and Mitchell G. Scott

Limited Linear Range of the Abbott AxSYM Serum and Erythrocyte Folate Methods
Clin Chem 1999 45: 582-583. [Full Text] [PDF]  

Richard J. Tyhach, Michael Mayer, and Lea Salpeter

More on Interference of N-Acetylcysteine in Measurement of Acetaminophen • The authors of the letter cited above respond:
Clin Chem 1999 45: 584. [Full Text] [PDF]  

Graham F. Cope

Simple Colorimetric Procedures to Determine Smoking Status
Clin Chem 1999 45: 585. [Full Text] [PDF]  

Book Reviews:

Marcia Eisenberg

Forensic DNA Profiling Protocols. Patrick J. Lincoln and Jim Thomson. Totowa, NJ: Humana Press, 1998, 309 pp., $79.50. ISBN 0-896-03443-7.
Clin Chem 1999 45: 586. [Full Text] [PDF]  

Edward Wong

Clinical Laboratory Diagnostics: Use and Assessment of Clinical Laboratory Results. Lothar Thomas. Frankfurt/Main, Germany: TH-Books Verlagsgeselschaft, 1998, 1727 pp., $149.00. ISBN 3-9805215-4-0.
Clin Chem 1999 45: 586. [Full Text]  

Correction:

Katy Dewitte, Dietmar Stöckl, and Linda M. Thienpont

Reliability of Measurement of Ionized Magnesium in Ultrafiltrate
Clin Chem 1999 45: 588-589. [Full Text] [PDF]  

Obituary:

Nathan Gochman

Lemuel J. Bowie, PhD (1944–1998)
Clin Chem 1999 45: 590. [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 1999 45: 591-592. [Full Text] [PDF]  

Clin Chem 1999 45: 592. [Full Text]  

Clin Chem 1999 45: 592. [Full Text]  

Notice of Duplicate Publication:

J.M. del Rey, A.H. Madrid, J.M. Valino, J. Rubi, J. Mercader, C. Moro, and E. Ripoll

Cardiac Troponin I and Minor Cardiac Damage: Biochemical Markers in a Clinical Model of Myocardial Lesions
Clin Chem 1999 45: 587. [Full Text] [PDF]  

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