Molecular Diagnostics and Genetics:

Fabiana Fini, Giorgio Gallinella, Stefano Girotti, Marialuisa Zerbini, and Monica Musiani

Development of a Chemiluminescence Competitive PCR for the Detection and Quantification of Parvovirus B19 DNA Using a Microplate Luminometer
Clin Chem 1999 45: 1391-1396. [Abstract] [Full Text] [PDF]  

Alice Ylikoski, Minna Sjöroos, Åke Lundwall, Matti Karp, Timo Lövgren, Hans Lilja, and Antti Iitiä

Quantitative Reverse Transcription-PCR Assay with an Internal Standard for the Detection of Prostate-specific Antigen mRNA
Clin Chem 1999 45: 1397-1407. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Hugues Henry, Florian Froehlich, Renaud Perret, Jean-Daniel Tissot, Barbara Eilers-Messerli, Daniel Lavanchy, Carlo Dionisi-Vici, Jean-Jacques Gonvers, and Claude Bachmann

Microheterogeneity of Serum Glycoproteins in Patients with Chronic Alcohol Abuse Compared with Carbohydrate-deficient Glycoprotein Syndrome Type I
Clin Chem 1999 45: 1408-1413. [Abstract] [Full Text] [PDF]  

Robert H. Christenson, Hemant Vaidya, Yvonne Landt, Roger S. Bauer, Sol F. Green, Fred A. Apple, Ann Jacob, Gerald R. Magneson, Sumitra Nag, Alan H.B. Wu, and Hassan M.E. Azzazy

Standardization of Creatine Kinase-MB (CK-MB) Mass Assays: The Use of Recombinant CK-MB as a Reference Material
Clin Chem 1999 45: 1414-1423. [Abstract] [Full Text] [PDF] Correction  

Lipids and Lipoproteins:

Sung Han Kim, Ji Hyun Bae, Jae Jin Chae, Un Kyung Kim, Seong-Joon Choe, Yong Namkoong, Hyo-Soo Kim, Young-Bae Park, and Chung Choo Lee

Long-Distance PCR-based Screening for Large Rearrangements of the LDL Receptor Gene in Korean Patients with Familial Hypercholesterolemia
Clin Chem 1999 45: 1424-1430. [Abstract] [Full Text] [PDF]  

Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka, Eiko Hidaka, Yoshiyuki Kondo, and Tsutomu Katsuyama

Characterization of Apolipoprotein E-containing Lipoproteins in Cerebrospinal Fluid: Effect of Phenotype on the Distribution of Apolipoprotein E
Clin Chem 1999 45: 1431-1438. [Abstract] [Full Text] [PDF]  

Bruno Guerci, Helena Antebi, Laurent Meyer, Vincent Durlach, Olivier Ziegler, Jean-Pierre Nicolas, Louis-Gerald Alcindor, and Pierre Drouin

Increased Ability of LDL from Normolipidemic Type 2 Diabetic Women to Generate Peroxides
Clin Chem 1999 45: 1439-1448. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Gordon D. MacFarlane, Daniel G. Scheller, Diana L. Ersfeld, Leslie M. Shaw, Raman Venkatarmanan, Laszlo Sarkozi, Richard Mullins, and Bonnie R. Fox

Analytical Validation of the PRO-Trac II ELISA for the Determination of Tacrolimus (FK506) in Whole Blood
Clin Chem 1999 45: 1449-1458. [Abstract] [Full Text] [PDF]  

M. Rezaul Haque and J. Howard Bradbury

Simple Method for Determination of Thiocyanate in Urine
Clin Chem 1999 45: 1459-1464. [Abstract] [Full Text] [PDF]  

Thomas P. Moyer, Zelalem Temesgen, Robert Enger, Lynn Estes, Joel Charlson, Lawrence Oliver, and Alan Wright

Drug Monitoring of Antiretroviral Therapy for HIV-1 Infection: Method Validation and Results of a Pilot Study
Clin Chem 1999 45: 1465-1476. [Abstract] [Full Text] [PDF]  

C. Michael Stein, John J. Murray, and Alastair J.J. Wood

Inhibition of Stimulated Interleukin-2 Production in Whole Blood: A Practical Measure of Cyclosporine Effect
Clin Chem 1999 45: 1477-1484. [Abstract] [Full Text] [PDF]  

Robert Kronstrand, Sophie Förstberg-Peterson, Bertil KÅgedal, Johan Ahlner, and Göran Larson

Codeine Concentration in Hair after Oral Administration Is Dependent on Melanin Content
Clin Chem 1999 45: 1485-1494. [Abstract] [Full Text] [PDF]  

Hematology:

Fey P.L. van der Dijs, Marcel Volmer, Dieuwke G. van Gijssel-Wiersma, Jan W. Smit, Reind van Veen, and Frits A.J. Muskiet

Predictive Value of Cord Blood Hematological Indices and Hemoglobin Barts for the Detection of Heterozygous -Thalassemia-2 in an African-Caribbean Population
Clin Chem 1999 45: 1495-1500. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Mark Sarno, Helen Powell, Gayle Tjersland, Donald Schoendorfer, Holden Harris, Kimberly Adams, Peggy Ogata, and G. Russell Warnick

A Collection Method and High-Sensitivity Enzyme Immunoassay for Sweat Pyridinoline and Deoxypyridinoline Cross-Links
Clin Chem 1999 45: 1501-1509. [Abstract] [Full Text] [PDF]  

Alessandro Rubinacci, Raffaella Melzi, Maria Zampino, Armando Soldarini, and Isabella Villa

Total and Free Deoxypyridinoline after Acute Osteoclast Activity Inhibition
Clin Chem 1999 45: 1510-1516. [Abstract] [Full Text] [PDF]  

Mark J. Magera, Jean M. Lacey, Bruno Casetta, and Piero Rinaldo

Method for the Determination of Total Homocysteine in Plasma and Urine by Stable Isotope Dilution and Electrospray Tandem Mass Spectrometry
Clin Chem 1999 45: 1517-1522. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Anja Kessler and Lothar Siekmann

Measurement of Urea in Human Serum by Isotope Dilution Mass Spectrometry: A Reference Procedure
Clin Chem 1999 45: 1523-1529. [Abstract] [Full Text] [PDF]  

Cyril Petibois, Vincent Rigalleau, Anne-Marie Melin, Annie Perromat, Georges Cazorla, Henri Gin, and Gérard Déléris

Determination of Glucose in Dried Serum Samples by Fourier-Transform Infrared Spectroscopy
Clin Chem 1999 45: 1530-1535. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Jan Møller, Karsten Rasmussen, and Lene Christensen

External Quality Assessment of Methylmalonic Acid and Total Homocysteine
Clin Chem 1999 45: 1536-1542. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Benoit Dugué, Esa Leppänen, and Ralph Gräsbeck

Preanalytical Factors (Biological Variation) and the Measurement of Serum Soluble Intercellular Adhesion Molecule-1 in Humans: Influence of the Time of Day, Food Intake, and Physical and Psychological Stress
Clin Chem 1999 45: 1543-1547. [Abstract] [Full Text] [PDF]  

Patrick C. D'Haese, Marie-Madeleine Couttenye, Ludwig V. Lamberts, Monique M. Elseviers, William G. Goodman, Iris Schrooten, Walter E. Cabrera, and Marc E. De Broe

Aluminum, Iron, Lead, Cadmium, Copper, Zinc, Chromium, Magnesium, Strontium, and Calcium Content in Bone of End-Stage Renal Failure Patients
Clin Chem 1999 45: 1548-1556. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Sandra Guaita, Josep M^A Simó, Natàlia Ferré, Jorge Joven, and Jordi Camps

Evaluation of a Particle-enhanced Turbidimetric Immunoassay for the Measurement of Immunoglobulin E in an ILab 900 Analyzer
Clin Chem 1999 45: 1557-1561. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Jong Weon Choi, Soo Hwan Pai, Moon Whan Im, and Soon Ki Kim

Change in Transferrin Receptor Concentrations with Age
Clin Chem 1999 45: 1562-1563. [Full Text] [PDF]  

Angela Brieger, Jörg Trojan, Jochen Raedle, W. Kurt Roth, and Stefan Zeuzem

Identification of Germline Mutations in Hereditary Nonpolyposis Colorectal Cancer Using Base Excision Sequence Scanning Analysis
Clin Chem 1999 45: 1564-1567. [Full Text] [PDF]  

Joan Carles Escolà-Gil, Oscar Jorba, Josep Julve-Gil, Francesc González-Sastre, Jordi Ordóñez-Llanos, and Francisco Blanco-Vaca

Pitfalls of Direct HDL-Cholesterol Measurements in Mouse Models of Hyperlipidemia and Atherosclerosis
Clin Chem 1999 45: 1567-1569. [Full Text] [PDF]  

Maddalena Smid, Fiorenza Lagona, Lara de Benassuti, Augusto Ferrari, Maurizio Ferrari, and Laura Cremonesi

Evaluation of Different Approaches for Fetal DNA Analysis from Maternal Plasma and Nucleated Blood Cells
Clin Chem 1999 45: 1570-1572. [Full Text] [PDF]  

Yan-Yun Wu, Rosario M. Delgado, Trey Sunderland, and Gyorgy Csako

Detection of a Deletion Polymorphism of the Human ₂-Macroglobulin Gene (A2M-2) by a Semi-Automated PCR-Single-Stranded Conformational Polymorphism Method
Clin Chem 1999 45: 1572-1573. [Full Text] [PDF]  

Letters to the Editor:

J. Douglas Ferry, Sandra Collins, Elizabeth Sykes, and Volkmar Henne

Effect of Serum Volume and Time of Exposure to Gel Barrier Tubes on Results for Progesterone by Roche Diagnostics Elecsys 2010 • A representative of Roche Diagnostics responds:
Clin Chem 1999 45: 1574-1575. [Full Text] [PDF]  

John A. Koepke

More on Calcium Ion Activity Buffers for Coagulation Testing
Clin Chem 1999 45: 1575-1576. [Full Text] [PDF]  

Phillip A. Isotalo, Donald C. Greenway, and James G. Donnelly

Metastatic Alveolar Rhabdomyosarcoma with Increased Serum Creatine Kinase MB and Cardiac Troponin T and Normal Cardiac Troponin I
Clin Chem 1999 45: 1576-1578. [Full Text] [PDF] Erratum  

Norman H.L. Chiu and Charles R. Cantor

Mass Spectrometry of Nucleic Acids
Clin Chem 1999 45: 1578. [Full Text] [PDF]  

Laurence M. Demers and Betty Smith

Application of the MediSense Precision-G Blood Glucose Testing System in a Neonatal Intensive Care Unit
Clin Chem 1999 45: 1578-1579. [Full Text] [PDF]  

Robert A. Hegele, Jon F. Merz, and Lawrence M. Silverman

Uncovering Rare Mutations: An Unforeseen Complication of Routine Genotyping of APOE • J. Merz and L. Silverman provide the following comment:
Clin Chem 1999 45: 1579-1581. [Full Text] [PDF]  

Book Reviews:

Pennell C. Painter

Principles of Clinical Laboratory Utilization and Consultation. Brenta G. Davis, Diana Mass, and Michael L. Bishop. Philadelphia, PA: WB Saunders, 1999, 709 pp., $75.00. ISBN 0-7216-6934-4.
Clin Chem 1999 45: 1582. [Full Text] [PDF]  

Theodore Peters, Jr

What Remains to Be Discovered. Mapping the Secrets of the Universe, the Origins of Life, and the Future of the Human Race. John Maddox. New York: Free Press, 1998, 434 pp., $26.00. ISBN 0-684-82292-X.
Clin Chem 1999 45: 1582-1583. [Full Text] [PDF]  

Dean A. Arvan and Patrice F. Spitalnik

Robbins Pathological Basis of Disease. Ramzi S. Cotran, Vinay Kumar, and Tucker Collins, eds. Philadelphia, PA: WB Saunders Co., 1999, 1472 pp., $75.00. ISBN 0-7216-7335-X.
Clin Chem 1999 45: 1583-1584. [Full Text] [PDF]  

Salvador F. Sena

Principles of Forensic Toxicology. Barry Levine, ed. Washington, DC: American Association for Clinical Chemistry, 1999, 394 pp., $49.00. ISBN 1-890889-07-7.
Clin Chem 1999 45: 1584. [Full Text] [PDF]  

Frederick L. Kiechle

Implementing Clinical Practice Guidelines. Carmi Z. Margolis and Shan Cretin, eds. Chicago, IL: American Hospital Association Press, 1999, 223 pp., $46.00. ISBN 1-55648-237-X.
Clin Chem 1999 45: 1584-1585. [Full Text] [PDF]  

Oak Ridge Conference:

Katie M. Smith

Introduction
Clin Chem 1999 45: 1586. [Full Text] [PDF]  

Hugh A. MacKenzie, Helen S. Ashton, Stephen Spiers, Yaochun Shen, Scott S. Freeborn, John Hannigan, John Lindberg, and Peter Rae

Advances in Photoacoustic Noninvasive Glucose Testing
Clin Chem 1999 45: 1587-1595. [Abstract] [Full Text] [PDF]  

Anthony P.F. Turner, Beining Chen, and Sergey A. Piletsky

In Vitro Diagnostics in Diabetes: Meeting the Challenge
Clin Chem 1999 45: 1596-1601. [Abstract] [Full Text] [PDF]  

Howard B. Urnovitz, Jerrilyn C. Sturge, Toby D. Gottfried, and William H. Murphy

Urine Antibody Tests: New Insights into the Dynamics of HIV-1 Infection
Clin Chem 1999 45: 1602-1613. [Abstract] [Full Text] [PDF]  

Francisco V. Alvarez, Jitka Olander, Dan Crimmins, Belén Prieto, Ana Paz, Rebeca Alonso, Sharon Porter, Jay Hess, Robert D. Crist, Yvonne Landt, and Jack H. Ladenson

Development, Characterization, and Use of Monoclonal Antibodies Made to Antigens Expressed on the Surface of Fetal Nucleated Red Blood Cells
Clin Chem 1999 45: 1614-1620. [Abstract] [Full Text] [PDF]  

Jason J. Burmeister and Mark A. Arnold

Evaluation of Measurement Sites for Noninvasive Blood Glucose Sensing with Near-Infrared Transmission Spectroscopy
Clin Chem 1999 45: 1621-1627. [Abstract] [Full Text] [PDF]  

Sumedha D. Jayasena

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics
Clin Chem 1999 45: 1628-1650. [Abstract] [Full Text] [PDF]  

Stephen F. Malin, Timothy L. Ruchti, Thomas B. Blank, Suresh N. Thennadil, and Stephen L. Monfre

Noninvasive Prediction of Glucose by Near-Infrared Diffuse Reflectance Spectroscopy
Clin Chem 1999 45: 1651-1658. [Abstract] [Full Text] [PDF]  

Rachel M. Ostroff, Deborah Hopkins, Ayla B. Haeberli, Wahab Baouchi, and Barry Polisky

Thin Film Biosensor for Rapid Visual Detection of Nucleic Acid Targets
Clin Chem 1999 45: 1659-1664. [Abstract] [Full Text] [PDF]  

Michael E. Collison, Philip J. Stout, Tatyana S. Glushko, Kristen N. Pokela, Debra J. Mullins-Hirte, Joel R. Racchini, Melissa A. Walter, Steve P. Mecca, Joanna Rundquist, John J. Allen, Michael E. Hilgers, and Thomas B. Hoegh

Analytical Characterization of Electrochemical Biosensor Test Strips for Measurement of Glucose in Low-Volume Interstitial Fluid Samples
Clin Chem 1999 45: 1665-1673. [Abstract] [Full Text] [PDF]  

Abstracts of Oak Ridge Posters:

Philip Stout, Kristen Pokela, Debra Mullins-Hirte, Thomas Hoegh, Michael Hilgers, Ann Thorp, Michael Collison, and Tatyana Glushko

Site-to-Site Variation of Glucose in Interstitial Fluid Samples and Correlation to Venous Plasma Glucose
Clin Chem 1999 45: 1674-1675. [Full Text] [PDF]  

Tim Dubrovsky, S-C. Jane Tsai, and Salvatore J. Salamone

Immobilization of Monolayers of Fc-binding Receptors on Planar Solid Supports
Clin Chem 1999 45: 1675-1676. [Full Text] [PDF]  

Donald E. Brooks, Dana V. Devine, Paul C. Harris, Joanne E. Harris, Mark E. Miller, Andrew D. Olal, Linda J. Spiller, and Zongen C. Xie

RAMP^TM: A Rapid, Quantitative Whole Blood Immunochromatographic Platform for Point-of-Care Testing
Clin Chem 1999 45: 1676-1678. [Full Text] [PDF]  

Bernhard P.H. Schaffar, Heinz Kontschieder, Christoph Ritter, and Hans Berger

Highly Miniaturized and Integrated Biosensor for Analysis of Whole Blood Samples
Clin Chem 1999 45: 1678-1679. [Full Text] [PDF]  

Christopher Uhegbu, Michael Reidy, Pravin Soni, Michael Tierney, Michelle Oliva, and Janet Tamada

Management of Interferences in a Transdermal, Noninvasive Glucose Monitoring Device
Clin Chem 1999 45: 1679-1681. [Full Text] [PDF]  

Michael J. Tierney, Yalia Jayalakshmi, Norman A. Parris, Michael P. Reidy, Christopher Uhegbu, and Prema Vijayakumar

Design of a Biosensor for Continual, Transdermal Glucose Monitoring
Clin Chem 1999 45: 1681-1683. [Full Text] [PDF]  

Richard H. Smith, William J. Lemon, Judith L. Erb, John R. Erb-Downward, James G. Downward, Otho E. Ulrich, and James L. Wittliff

Development of Kinetic Ligand-binding Assays Using a Fiber Optic Sensor
Clin Chem 1999 45: 1683-1685. [Full Text] [PDF]  

Alain Rousseau and Michel Canton

New Miniaturized Highly Sensitive Immunoassay Device for Quantitative Measurement of Soluble or Particular Antigen or Antibodies in a Liquid Sample
Clin Chem 1999 45: 1685-1687. [Full Text] [PDF]  

Lester A. Sodickson

Lateral Tissue Inhomogeneity: A Missing Link in Photoplethysmographic Noninvasive Measurement of Arterial Blood Constituents
Clin Chem 1999 45: 1687-1689. [Full Text] [PDF]  

Man-Sheung Chan, Donald Kuty, John Pepin, Norman Parris, Russ Potts, Mike Reidy, Mike Tierney, Chris Uhegbu, and Yalia Jayalakshmi

Materials for Fabricating Biosensors for Transdermal Glucose Monitoring
Clin Chem 1999 45: 1689-1690. [Full Text] [PDF]  

Marek Wojciechowski, Rebecca Sundseth, Mario Moreno, and Robert Henkens

Multichannel Electrochemical Detection System for Quantitative Monitoring of PCR Amplification
Clin Chem 1999 45: 1690-1693. [Full Text] [PDF]  

Roy Chen, Larry Lowe, Jerry D. Wilson, Eric Crowther, Kifle Tzeggai, Jim E. Bishop, and Rudi Varro

Simultaneous Quantification of Six Human Cytokines in a Single Sample Using Microparticle-based Flow Cytometric Technology
Clin Chem 1999 45: 1693-1694. [Full Text] [PDF]  

Correction:

Correction for vol. 45, p. 1058
Clin Chem 1999 45: 1585. [Full Text] [PDF]  

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