Editorials:

Lawrence Sweetman

Newborn Screening by Tandem Mass Spectrometry: Gaining Experience
Clin Chem 2001 47: 1937-1938. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Agustín Ruiz, Guillermo Antiñolo, Irene Marcos, and Salud Borrego

Novel Technique for Scanning of Codon 634 of the RET Protooncogene with Fluorescence Resonance Energy Transfer and Real-Time PCR in Patients with Medullary Thyroid Carcinoma
Clin Chem 2001 47: 1939-1944. [Abstract] [Full Text] [PDF]  

Thomas H. Zytkovicz, Eileen F. Fitzgerald, Deborah Marsden, Cecilia A. Larson, Vivian E. Shih, Donna M. Johnson, Arnold W. Strauss, Anne Marie Comeau, Roger B. Eaton, and George F. Grady

Tandem Mass Spectrometric Analysis for Amino, Organic, and Fatty Acid Disorders in Newborn Dried Blood Spots: A Two-Year Summary from the New England Newborn Screening Program
Clin Chem 2001 47: 1945-1955. [Abstract] [Full Text] [PDF]  

Nicolas von Ahsen, Carl T. Wittwer, and Ekkehard Schütz

Oligonucleotide Melting Temperatures under PCR Conditions: Nearest-Neighbor Corrections for Mg²⁺, Deoxynucleotide Triphosphate, and Dimethyl Sulfoxide Concentrations with Comparison to Alternative Empirical Formulas
Clin Chem 2001 47: 1956-1961. [Abstract] [Full Text] [PDF] Supplemental Data  

Enzymes and Protein Markers:

Magohei Yamada, Yoji Marui, Chozo Hayashi, Yasuyoshi Miki, and Shoji Takemura

New Thiocholine Ester Substrates for the Assay of Human Serum Cholinesterase
Clin Chem 2001 47: 1962-1966. [Abstract] [Full Text] [PDF]  

Hiroshi Yamamichi, Shinpei Kasakura, Shunzi Yamamori, Ryu Iwasaki, Takumi Jikimoto, Sugayo Kanagawa, Jiro Ohkawa, Shunichi Kumagai, and Masahiro Koshiba

Creatine Kinase Gene Mutation in a Patient with Muscle Creatine Kinase Deficiency
Clin Chem 2001 47: 1967-1973. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Sridevi Devaraj, Shaina V. Hirany, Raymond F. Burk, and Ishwarlal Jialal

Divergence between LDL Oxidative Susceptibility and Urinary F₂-Isoprostanes as Measures of Oxidative Stress in Type 2 Diabetes
Clin Chem 2001 47: 1974-1979. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Gunnel Ceder and Alan Wayne Jones

Concentration Ratios of Morphine to Codeine in Blood of Impaired Drivers as Evidence of Heroin Use and not Medication with Codeine
Clin Chem 2001 47: 1980-1984. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Randie R. Little, Curt L. Rohlfing, Hsiao-Mei Wiedmeyer, Gary L. Myers, David B. Sacks, and David E. Goldstein

The National Glycohemoglobin Standardization Program: A Five-Year Progress Report
Clin Chem 2001 47: 1985-1992. [Abstract] [Full Text] [PDF]  

Mark M. Kushnir, Gabor Komaromy-Hiller, Bori Shushan, Francis M. Urry, and William L. Roberts

Analysis of Dicarboxylic Acids by Tandem Mass Spectrometry. High-Throughput Quantitative Measurement of Methylmalonic Acid in Serum, Plasma, and Urine
Clin Chem 2001 47: 1993-2002. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Udo zur Stadt, Johannes Rischewski, Reinhard Schneppenheim, and Hartmut Kabisch

Denaturing HPLC for Identification of Clonal T-Cell Receptor Rearrangements in Newly Diagnosed Acute Lymphoblastic Leukemia
Clin Chem 2001 47: 2003-2011. [Abstract] [Full Text] [PDF]  

Kevin Mills, Philippa B. Mills, Peter T. Clayton, Andrew W. Johnson, David B. Whitehouse, and Bryan G. Winchester

Identification of ₁-Antitrypsin Variants in Plasma with the Use of Proteomic Technology
Clin Chem 2001 47: 2012-2022. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Mabel Aleanzi, Ana María Demonte, Cecilia Esper, Silvia Garcilazo, and Marta Waggener

Celiac Disease: Antibody Recognition against Native and Selectively Deamidated Gliadin Peptides
Clin Chem 2001 47: 2023-2028. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Hubert W. Vesper, S. Jay Smith, Cynthia Audain, and Gary L. Myers

Comparison Study of Urinary Pyridinoline and Deoxypyridinoline Measurements in 13 US Laboratories
Clin Chem 2001 47: 2029-2031. [Extract] [Full Text] [PDF] Data Supplements  

Erik J. Uhlmann, Karl G. Hock, Charla Issitt, M. Rhonda Sneeringer, Denise R. Cervelli, Rober T. Gorman, and Mitchell G. Scott

Reference Intervals for Plasma Cystatin C in Healthy Volunteers and Renal Patients, as Measured by the Dade Behring BN II System, and Correlation with Creatinine
Clin Chem 2001 47: 2031-2033. [Extract] [Full Text] [PDF]  

Pascal Kintz, Jean-Pierre Goullé, Vincent Cirimele, and Bertrand Ludes

Window of Detection of -Hydroxybutyrate in Blood and Saliva
Clin Chem 2001 47: 2033-2034. [Extract] [Full Text] [PDF]  

György Sölétormos, Per Hyltoft Petersen, and Dorte Nielsen

Computer-simulated Tumor-Marker Data Used to Compare Progression Criteria for Cytokeratin Tissue Polypeptide Antigen in Metastatic Breast Cancer
Clin Chem 2001 47: 2035-2037. [Extract] [Full Text] [PDF] Data Supplement  

Consuelo Fernández-Miranda, Marta Sanz, Angel de la Calle, Carmelo Loinaz, Pilar Gómez, Pilar Díaz-Rubio, Agustín Gómez de la Cámara, and Enrique Moreno

Determinants of Increased Plasma Homocysteine in 221 Stable Liver Transplant Patients
Clin Chem 2001 47: 2037-2040. [Extract] [Full Text] [PDF] Data Supplements  

Donald H. Chace, James C. DiPerna, Theodore A. Kalas, Ronald W. Johnson, and Edwin W. Naylor

Rapid Diagnosis of Methylmalonic and Propionic Acidemias: Quantitative Tandem Mass Spectrometric Analysis of Propionylcarnitine in Filter-Paper Blood Specimens Obtained from Newborns
Clin Chem 2001 47: 2040-2044. [Extract] [Full Text] [PDF]  

Ahmad Hamwi, Thomas Vukovich, Oswald Wagner, Helmut Rumpold, Roswitha Spies, Martina Stich, and Carina Langecker

Evaluation of Turbidimetric High-Sensitivity C-Reactive Protein Assays for Cardiovascular Risk Estimation
Clin Chem 2001 47: 2044-2046. [Extract] [Full Text] [PDF]  

Franca Pagani and Mauro Panteghini

5'-Nucleotidase in the Detection of Increased Activity of the Liver Form of Alkaline Phosphatase in Serum
Clin Chem 2001 47: 2046-2048. [Extract] [Full Text] [PDF]  

Martin J. Hessner, Kenneth D. Friedman, Karl V. Voelkerding, Suzanne Huber, Daniel Ryan, Bonnie Nuccie, and Marlies Ledford

Multisite Study for Genotyping of the Factor II (Prothrombin) G20210A Mutation by the Invader Assay
Clin Chem 2001 47: 2048-2050. [Extract] [Full Text] [PDF]  

Arve Ulvik and Per Magne Ueland

Single Nucleotide Polymorphism (SNP) Genotyping in Unprocessed Whole Blood and Serum by Real-Time PCR: Application to SNPs Affecting Homocysteine and Folate Metabolism
Clin Chem 2001 47: 2050-2053. [Extract] [Full Text] [PDF]  

Nicholas M. Brown, Susan Bernacki, Victoria M. Pratt, and Timothy T. Stenzel

Fluorescent, Multiplexed, Automated, Primer-Extension Assay for 3120+1GA and I148T Mutations in Cystic Fibrosis
Clin Chem 2001 47: 2053-2055. [Extract] [Full Text] [PDF]  

Lorenz Risch, Roberto Herklotz, Alfred Blumberg, and Andreas R. Huber

Effects of Glucocorticoid Immunosuppression on Serum Cystatin C Concentrations in Renal Transplant Patients
Clin Chem 2001 47: 2055-2059. [Extract] [Full Text] [PDF]  

Laurence Pieroni, Lina Khalil, Frederic Charlotte, Thierry Poynard, Annie Piton, Bernard Hainque, and Françoise Imbert-Bismut

Comparison of Bathophenanthroline Sulfonate and Ferene as Chromogens in Colorimetric Measurement of Low Hepatic Iron Concentration
Clin Chem 2001 47: 2059-2061. [Extract] [Full Text] [PDF]  

Klaus Jung, Michael Lein, Katharina von Hösslin, Brigitte Brux, Dietmar Schnorr, Stefan A. Loening, and Pranav Sinha

Osteoprotegerin in Serum as a Novel Marker of Bone Metastatic Spread in Prostate Cancer
Clin Chem 2001 47: 2061-2063. [Extract] [Full Text] [PDF]  

J. Keith Pinckard, Janet Zahn, Lori Ashby, Curtis A. Parvin, and Mitchell G. Scott

Falsely Increased i-STAT Chloride Results for Blood Samples with Increased Urea
Clin Chem 2001 47: 2064-2066. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Alun Price, Christine Burgin, Ian Catch, and Martin Cruise

Functional Sensitivity and Recovery of Thyroid-stimulating Hormone
Clin Chem 2001 47: 2067. [Extract] [Full Text] [PDF]  

Néstor A. Chamoles, Mariana B. Blanco, Sonia Iorcansky, Daniela Gaggioli, Norma Spécola, and Carina Casentini

Retrospective Diagnosis of GM1 Gangliosidosis by Use of a Newborn-Screening Card
Clin Chem 2001 47: 2068. [Extract] [Full Text] [PDF]  

Maria Stella Graziani, Giampaolo Merlini, Arthur R. Bradwell, Mark T. Drayson, and Graham P. Mead

Measurement of Free Light Chains in Urine • Drs. Bradwell, Drayson, and Mead respond:
Clin Chem 2001 47: 2069-2070. [Extract] [Full Text] [PDF]  

Kayoko Tateishi, Eugene P. DiMagno, and George G. Klee

Plasma Islet Amyloid Polypeptide Is Not an Effective Tumor Marker for Pancreatic Cancer Even When Protease Inhibitors and Rapid Freezing of Specimens Are Utilized
Clin Chem 2001 47: 2071-2073. [Extract] [Full Text] [PDF]  

Giuseppe Lippi and Massimo Franchini

Laboratory Screening for Abnormalities of Primary Hemostasis: What’s Next?
Clin Chem 2001 47: 2071. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Thomas J. Ryan

Capillary Electro-Chromatography and Pressurized Flow Capillary Electro-Chromatography: An Introduction. Ira S. Krull, Robert L. Stevenson, Kavita Mistry, and Michael E. Swartz. New York: HNB Publishing, 2000, 240 pp., $54.00. ISBN 0-9664286-2-5.
Clin Chem 2001 47: 2074-2075. [Extract] [Full Text] [PDF]  

Pier Giorgio Righetti

Clinical and Forensic Applications of Capillary Electrophoresis. J.R. Petersen, A.M. Mohammad, eds. Totowa, NJ: Humana Press, 2001, 453 pp., $150.00. ISBN 0-89603-645-6.
Clin Chem 2001 47: 2074. [Extract] [Full Text] [PDF]  

Robert Rej and Carol S. Norton-Wenzel

EP Evaluator-CLIA (EE-CLIA) for Evaluating Clinical Laboratory Methods (Consultant’s Version with Rapid Results Entry). Kennett Square, PA: David G. Rhoads Associates, Inc., 2000, 3 diskettes and manual (142 + 33 pp.), $695.00.
Clin Chem 2001 47: 2075-2076. [Extract] [Full Text] [PDF]  

Rosa Sierra-Amor

CRC Handbook of Laboratory Safety, 5th ed. A. Keith Furr, ed. Boca Raton, FL: CRC Press LCC, 2000, 774 pp., $149.99. ISBN 0-8493-2523-4.
Clin Chem 2001 47: 2075. [Extract] [Full Text] [PDF]  

Theodore Peters, Jr.

Landmark Papers in Cell Biology. Joseph G. Gall and J. Richard McIntosh, eds. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2000, 554 pp., hardcover, $45.00. ISBN 0-87969-602-8.
Clin Chem 2001 47: 2077. [Extract] [Full Text] [PDF]  

Correction:

Correction for vol. 47, p. 1204
Clin Chem 2001 47: 2077. [Extract] [Full Text] [PDF]  

Abstracts of the 2001 San Diego Conference:

The San Diego Conference New Technologies for Molecular Diagnostics November 8–10, 2001
Clin Chem 2001 47: 2078-2085. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2001 47: 2086. [Extract] [Full Text] [PDF]  

Accent^®:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2001 47: 2087-2088. [Extract] [Full Text] [PDF]  

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