Minireview:

Wolfgang Jelkmann

Pitfalls in the Measurement of Circulating Vascular Endothelial Growth Factor
Clin Chem 2001 47: 617-623. [Abstract] [Full Text] [PDF]  

Michael J. Duffy

Carcinoembryonic Antigen as a Marker for Colorectal Cancer: Is It Clinically Useful?
Clin Chem 2001 47: 624-630. [Abstract] [Full Text] [PDF]  

Opinion:

Thomas A. Stamey

Preoperative Serum Prostate-specific Antigen (PSA) Below 10 µg/L Predicts Neither the Presence of Prostate Cancer Nor the Rate of Postoperative PSA Failure
Clin Chem 2001 47: 631-634. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Robert H. Lipsky, Chiara M. Mazzanti, Joseph G. Rudolph, Ke Xu, Gopal Vyas, David Bozak, Marta Q. Radel, and David Goldman

DNA Melting Analysis for Detection of Single Nucleotide Polymorphisms
Clin Chem 2001 47: 635-644. [Abstract] [Full Text] [PDF]  

Anne Mette Høgh, Thomas Vauvert F. Hviid, Britta Christensen, Steen Sørensen, Rasmus D. Larsen, Steen Smidt-Jensen, Jens Bang, and John Philip

-, -, and -Globin mRNA in Blood Samples and CD71⁺ Cell Fractions from Fetuses and from Pregnant and Nonpregnant Women, with Special Attention to Identification of Fetal Erythroblasts
Clin Chem 2001 47: 645-653. [Abstract] [Full Text] [PDF]  

Sven Wellmann, Tillmann Taube, Krisztina Paal, Hagen Graf v. Einsiedel, Wilhelm Geilen, Georg Seifert, Cornelia Eckert, Günter Henze, and Karlheinz Seeger

Specific Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor (VEGF) Splice Variants by LightCycler Technology
Clin Chem 2001 47: 654-660. [Abstract] [Full Text] [PDF]  

Naomi Q. Hanson, Ömer Aras, Feng Yang, and Michael Y. Tsai

C677T and A1298C Polymorphisms of the Methylenetetrahydrofolate Reductase Gene: Incidence and Effect of Combined Genotypes on Plasma Fasting and Post-Methionine Load Homocysteine in Vascular Disease
Clin Chem 2001 47: 661-666. [Abstract] [Full Text] [PDF]  

Rossa W.K. Chiu, Michael F. Murphy, Carrie Fidler, Benny C.Y. Zee, James S. Wainscoat, and Y.M. Dennis Lo

Determination of RhD Zygosity: Comparison of a Double Amplification Refractory Mutation System Approach and a Multiplex Real-Time Quantitative PCR Approach
Clin Chem 2001 47: 667-672. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Arthur R. Bradwell, Hugh D. Carr-Smith, Graham P. Mead, Lian X. Tang, Paul J. Showell, Mark T. Drayson, and Roger Drew

Highly Sensitive, Automated Immunoassay for Immunoglobulin Free Light Chains in Serum and Urine
Clin Chem 2001 47: 673-680. [Abstract] [Full Text] [PDF]  

Pekka Sillanaukee and Ulf Olsson

Improved Diagnostic Classification of Alcohol Abusers by Combining Carbohydrate-deficient Transferrin and -Glutamyltransferase
Clin Chem 2001 47: 681-685. [Abstract] [Full Text] [PDF]  

Henning W. Woitge, Eva Horn, Andrea V. Keck, Beatrice Auler, Markus J. Seibel, and Martin Pecherstorfer

Biochemical Markers of Bone Formation in Patients with Plasma Cell Dyscrasias and Benign Osteoporosis
Clin Chem 2001 47: 686-693. [Abstract] [Full Text] [PDF]  

Patrick Garnero, Olivier Borel, and Pierre D. Delmas

Evaluation of a Fully Automated Serum Assay for C-Terminal Cross-Linking Telopeptide of Type I Collagen in Osteoporosis
Clin Chem 2001 47: 694-702. [Abstract] [Full Text] [PDF]  

Timo Piironen, Martti Nurmi, Kerttu Irjala, Olli Heinonen, Hans Lilja, Timo Lövgren, and Kim Pettersson

Measurement of Circulating Forms of Prostate-specific Antigen in Whole Blood Immediately after Venipuncture: Implications for Point-of-Care Testing
Clin Chem 2001 47: 703-711. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Thomas G. Cole, Constance A. Ferguson, David W. Gibson, and William L. Nowatzke

Optimization of ß-Quantification Methods for High-Throughput Applications
Clin Chem 2001 47: 712-721. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Raneem O. Salem, Majed A. Refaai, Joanne E. Cluette-Brown, Joshua W. Russo, and Michael Laposata

Fatty Acid Ethyl Esters in Liver and Adipose Tissues as Postmortem Markers for Ethanol Intake
Clin Chem 2001 47: 722-725. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Juerg Nussberger, Dorette B. Brunner, Juerg A. Nyfeler, Lilly Linder, and Hans R. Brunner

Measurement of Immunoreactive Angiotensin-(1–7) Heptapeptide in Human Blood
Clin Chem 2001 47: 726-729. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Cyril Petibois, Georges Cazorla, André Cassaigne, and Gérard Déléris

Plasma Protein Contents Determined by Fourier-Transform Infrared Spectrometry
Clin Chem 2001 47: 730-738. [Abstract] [Full Text] [PDF]  

Maarten L. Smit, Belinda A.J. Giesendorf, Jacqueline A.M. Vet, Frans J.M. Trijbels, and Henk J. Blom

Semiautomated DNA Mutation Analysis Using a Robotic Workstation and Molecular Beacons
Clin Chem 2001 47: 739-744. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Maximilian Ledochowski, Bernhard Widner, Christian Murr, and Dietmar Fuchs

Decreased Serum Zinc in Fructose Malabsorbers
Clin Chem 2001 47: 745-747. [Extract] [Full Text] [PDF]  

De Chen, Nihal A. Sarikaya, Han Gunn, Steven W. Martin, and John D. Young

ELISA Methodology for Detection of Modified Osteoprotegerin in Clinical Studies
Clin Chem 2001 47: 747-749. [Extract] [Full Text] [PDF]  

Maarten T.M. Raijmakers, Eva Maria Roes, Eric A.P. Steegers, Bas van der Wildt, and Wilbert H.M. Peters

Umbilical Cord and Maternal Plasma Thiol Concentrations in Normal Pregnancy
Clin Chem 2001 47: 749-751. [Extract] [Full Text] [PDF]  

Martin Beck, Arend Bökenkamp, Nicolas Liappis, and Michael J. Lentze

Effect of Storage on Phenylalanine and Tyrosine Measurements in Whole-Blood Samples
Clin Chem 2001 47: 751-753. [Extract] [Full Text] [PDF]  

Anna Lis Lauridsen, Peter Vestergaard, and Ebba Nexo

Mean Serum Concentration of Vitamin D-binding Protein (Gc Globulin) Is Related to the Gc Phenotype in Women
Clin Chem 2001 47: 753-756. [Extract] [Full Text] [PDF]  

Li-Yu Tsai, Shih-Meng Tsai, Me-Nung Lin, and Shu-Fen Liu

Effect of Hemoglobin Variants (Hb J, Hb G, and Hb E) on HbA1c Values as Measured by Cation-Exchange HPLC (Diamat)
Clin Chem 2001 47: 756-758. [Extract] [Full Text] [PDF]  

Donald H. Chace, James C. DiPerna, Barbara W. Adam, and W. Harry Hannon

Errors Caused by the Use of D,L-Octanoylcarnitine for Blood-Spot Calibrators
Clin Chem 2001 47: 758-760. [Extract] [Full Text] [PDF]  

Shirley J. Johnson, Diane H. Green, David A. Reed, and Linda S. Wood

Semiautomation of Nucleic Acid-based Assays for Chlamydia trachomatis and Neisseria gonorrhoeae,
Clin Chem 2001 47: 760-763. [Extract] [Full Text] [PDF]  

Kazuyuki Matsuda, Nobuo Hiratsuka, Takatoshi Koyama, Yuriko Kurihara, Osamu Hotta, Yoshihisa Itoh, and Kiyoko Shiba

Sensitive Method for Detection and Semiquantification of Bence Jones Protein by Cellulose Acetate Membrane Electrophoresis Using Colloidal Silver Staining
Clin Chem 2001 47: 763-766. [Extract] [Full Text] [PDF]  

Poonkuzhali Balasubramanian, Alok Srivastava, and Mammen Chandy

Stability of Busulfan in Frozen Plasma and Whole Blood Samples
Clin Chem 2001 47: 766-768. [Extract] [Full Text] [PDF]  

Chantal Thévenon, Michel Guichardant, and Michel Lagarde

Gas Chromatographic–Mass Spectrometric Measurement of 15-Deoxy-^12,14-prostaglandin J₂, the Peroxisome Proliferator-activated Receptor Ligand, in Urine
Clin Chem 2001 47: 768-770. [Extract] [Full Text] [PDF]  

Walter Mastropaolo, Adam Matheny, Jr, and Calvin A. Lang

Plasma Cholesterol Concentrations in Twin Children: Estimates of Genetic and Environmental Influences
Clin Chem 2001 47: 771. [Extract] [Full Text] [PDF]  

Martin Hersberger, Jacqueline Marti-Jaun, Katharina Rentsch, and Edgar Hänseler

Two Single-Tube Tetra-Primer Assays to Detect the CYP2C19*2 and *3 Alleles of S-Mephenytoin Hydroxylase
Clin Chem 2001 47: 772-774. [Extract] [Full Text] [PDF]  

Darren R. Hodgson, Simon J. Clayton, Fiona Girdler, Ian Brotherick, Brian Shenton, David Browell, Mary Stuart, Jayne C. Fox, Peter Ceuppens, Carole A. Foy, David Whitcombe, and Neil J. Gibson

ARMS^TM Allele-specific Amplification-based Detection of Mutant p53 DNA and mRNA in Tumors of the Breast,
Clin Chem 2001 47: 774-778. [Extract] [Full Text] [PDF]  

Leslie A. Perry and Anne Dawnay

Chemiluminescent Assay for Serum Thyroglobulin in the Management of Patients with Thyroid Carcinoma
Clin Chem 2001 47: 778-779. [Extract] [Full Text] [PDF]  

Néstor A. Chamoles, Mariana Blanco, and Daniela Gaggioli

Diagnosis of -L-Iduronidase Deficiency in Dried Blood Spots on Filter Paper: The Possibility of Newborn Diagnosis
Clin Chem 2001 47: 780-781. [Extract] [Full Text] [PDF]  

Gershwin K. Davis, Ralf Labugger, Jennifer E. Van Eyk, and Fred S. Apple

Cardiac Troponin T Is Not Detected in Western Blots of Diseased Renal Tissue
Clin Chem 2001 47: 782-783. [Extract] [Full Text] [PDF]  

History:

Louis Rosenfeld

The Chemical Work of Alexander and Jane Marcet
Clin Chem 2001 47: 784-792. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Katharine Hayden and Charles van Heyningen

Measurement of Total Protein Is a Useful Inclusion in Liver Function Test Profiles
Clin Chem 2001 47: 793-794. [Extract] [Full Text] [PDF]  

Miriam Almagor and Ofri Lavid-Levy

Effects of Blood-Collection Systems and Tubes on Hematologic, Chemical, and Coagulation Tests and on Plasma Hemoglobin
Clin Chem 2001 47: 794-795. [Extract] [Full Text] [PDF]  

Michael Vogeser, Klaus G. Parhofer, Heinrich Fürst, Karl Jacob, Ulrich C. Brödl, and Dietrich Seidel

Autoimmune Hypoglycemia Presenting as Seizure One Week after Surgery
Clin Chem 2001 47: 795-796. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 2001 47: 797. [Extract] [Full Text] [PDF]  

Accent^®:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2001 47: 798-799. [Extract] [Full Text] [PDF]  

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