Editorials:

Michael J. Bennett and Piero Rinaldo

The Metabolic Autopsy Comes of Age
Clin Chem 2001 47: 1145-1146. [Extract] [Full Text] [PDF]  

Reviews:

Elaine Lyon and Elizabeth L. Frank

Hereditary Hemochromatosis Since Discovery of the HFE Gene
Clin Chem 2001 47: 1147-1156. [Abstract] [Full Text] [PDF]  

Overview:

Uma Krishnamurti and Michael W. Steffes

Glycohemoglobin: A Primary Predictor of the Development or Reversal of Complications of Diabetes Mellitus
Clin Chem 2001 47: 1157-1165. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Donald H. Chace, James C. DiPerna, Brenda L. Mitchell, Bethany Sgroi, Lindsay F. Hofman, and Edwin W. Naylor

Electrospray Tandem Mass Spectrometry for Analysis of Acylcarnitines in Dried Postmortem Blood Specimens Collected at Autopsy from Infants with Unexplained Cause of Death
Clin Chem 2001 47: 1166-1182. [Abstract] [Full Text] [PDF]  

Jesper Worm, Anni Aggerholm, and Per Guldberg

In-Tube DNA Methylation Profiling by Fluorescence Melting Curve Analysis
Clin Chem 2001 47: 1183-1189. [Abstract] [Full Text] [PDF]  

Patricia M. Jones, Monica Moffitt, Delanie Joseph, Pamela A. Harthcock, Richard L. Boriack, Jamal A. Ibdah, Arnold W. Strauss, and Michael J. Bennett

Accumulation of Free 3-Hydroxy Fatty Acids in the Culture Media of Fibroblasts from Patients Deficient in Long-Chain L-3-Hydroxyacyl-CoA Dehydrogenase: A Useful Diagnostic Aid
Clin Chem 2001 47: 1190-1194. [Abstract] [Full Text] [PDF]  

Gloria A. Thomas, Diana L. Williams, and Steven A. Soper

Capillary Electrophoresis-based Heteroduplex Analysis with a Universal Heteroduplex Generator for Detection of Point Mutations Associated with Rifampin Resistance in Tuberculosis
Clin Chem 2001 47: 1195-1203. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

Christopher M. Lehman, Robert C. Blaylock, Donald P. Alexander, and George M. Rodgers

Discontinuation of the Bleeding Time Test without Detectable Adverse Clinical Impact
Clin Chem 2001 47: 1204-1211. [Abstract] [Full Text] [PDF]  

Svein Skeie, Geir Thue, and Sverre Sandberg

Interpretation of Hemoglobin A_1c (HbA_1c) Values among Diabetic Patients: Implications for Quality Specifications for HbA_1c
Clin Chem 2001 47: 1212-1217. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Judith A. Finlay, John R. Day, Cindy L. Evans, Robert Carlson, Kristine Kuus-Reichel, Lisa S. Millar, Stephen D. Mikolajczyk, Marcia Goodmanson, George G. Klee, and Harry G. Rittenhouse

Development of a Dual Monoclonal Antibody Immunoassay for Total Human Kallikrein 2
Clin Chem 2001 47: 1218-1224. [Abstract] [Full Text] [PDF]  

Anders Helander, Gunne Eriksson, Helena Stibler, and Jan-Olof Jeppsson

Interference of Transferrin Isoform Types with Carbohydrate-deficient Transferrin Quantification in the Identification of Alcohol Abuse
Clin Chem 2001 47: 1225-1233. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Mehran Haidari, Ebrahim Javadi, Mehry Kadkhodaee, and Arashmidos Sanati

Enhanced Susceptibility to Oxidation and Diminished Vitamin E Content of LDL from Patients with Stable Coronary Artery Disease
Clin Chem 2001 47: 1234-1240. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Michel Mourad, Jacques Malaise, Djamila Chaib Eddour, Martine De Meyer, Josiane König, Raf Schepers, Jean Paul Squifflet, and Pierre Wallemacq

Pharmacokinetic Basis for the Efficient and Safe Use of Low-Dose Mycophenolate Mofetil in Combination with Tacrolimus in Kidney Transplantation
Clin Chem 2001 47: 1241-1248. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Hisahiko Iwamoto, Yoshihiro Motomiya, Keisuke Miura, Masayo Morisawa, Yoshimichi Yoshimura, and Ikuro Maruyama

Immunochemical Assay of Hemoglobin with N-(Carboxymethyl)lysine at Lysine 66 of the ß Chain
Clin Chem 2001 47: 1249-1255. [Abstract] [Full Text] [PDF]  

Veera Vihma, Herman Adlercreutz, Aila Tiitinen, Paula Kiuru, Kristiina Wähälä, and Matti J. Tikkanen

Quantitative Determination of Estradiol Fatty Acid Esters in Human Pregnancy Serum and Ovarian Follicular Fluid
Clin Chem 2001 47: 1256-1262. [Abstract] [Full Text] [PDF]  

Ömer Aras, Michael Y. Tsai, Naomi Q. Hanson, Robert Bailey, Gundu Rao, and Donald B. Hunninghake

Cystatin C Is an Independent Predictor of Fasting and Post-Methionine Load Total Homocysteine Concentrations among Stable Renal Transplant Recipients
Clin Chem 2001 47: 1263-1268. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Tero Soukka, Janika Paukkunen, Harri Härmä, Stefan Lönnberg, Hanne Lindroos, and Timo Lövgren

Supersensitive Time-resolved Immunofluorometric Assay of Free Prostate-specific Antigen with Nanoparticle Label Technology
Clin Chem 2001 47: 1269-1278. [Abstract] [Full Text] [PDF]  

Christopher V. Eddy and Mark A. Arnold

Near-Infrared Spectroscopy for Measuring Urea in Hemodialysis Fluids
Clin Chem 2001 47: 1279-1286. [Abstract] [Full Text] [PDF]  

Marcel Volmer, Jules C.M. de Vries, and Henk M.J. Goldschmidt

Infrared Analysis of Urinary Calculi by a Single Reflection Accessory and a Neural Network Interpretation Algorithm
Clin Chem 2001 47: 1287-1296. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Momoko Komatsu, Daisuke Kobayashi, Kaori Saito, Daisuke Furuya, Atsuhito Yagihashi, Hiroshi Araake, Naoki Tsuji, Sumio Sakamaki, Yoshiro Niitsu, and Naoki Watanabe

Tumor Necrosis Factor- in Serum of Patients with Inflammatory Bowel Disease as Measured by a Highly Sensitive Immuno-PCR
Clin Chem 2001 47: 1297-1301. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Robert Zawydiwski, Dennis L. Sprecher, Michael J. Evelegh, Peter Horsewood, Carol Carte, and Michelle Patterson

A Novel Test for the Measurement of Skin Cholesterol
Clin Chem 2001 47: 1302-1304. [Extract] [Full Text] [PDF]  

Peter Wiesli, Friedrich E. Maly, Alfredo Meniconi, Wolfgang Czerwenka, Ulrich Hoffmann, Wilhelm Vetter, and Georg Schulthess

Chlamydia pneumoniae Seropositivity and Hyperhomocysteinemia Are Linked in Patients with Atherosclerosis
Clin Chem 2001 47: 1304-1306. [Extract] [Full Text] [PDF]  

Zheng Zhao, N. Magus Hjelm, Christopher W.K. Lam, and Chung S. Ho

One-Step Solid-Phase Extraction Procedure for F₂-Isoprostanes
Clin Chem 2001 47: 1306-1308. [Extract] [Full Text] [PDF]  

Dilip K. Rai, William J. Griffiths, Gunvor Alvelius, and Britta Landin

Electrospray Mass Spectrometry: An Efficient Method to Detect Silent Hemoglobin Variants Causing Erythrocytosis
Clin Chem 2001 47: 1308-1311. [Extract] [Full Text] [PDF] Supplemental Data  

Cristina Dassi, Paolo Brambilla, Stefano Signorini, Piermario Gerthoux, Pierangela Molteni, Raffaella Sala, and Paolo Mocarelli

Quantification of Aromatic Hydrocarbon Receptor (AHR) and Related Genes by Calibrated Reverse Transcription-PCR in Blood Mononuclear Cells
Clin Chem 2001 47: 1311-1314. [Extract] [Full Text] [PDF]  

Federica Paglia, Simona Dionisi, Simona De Geronimo, Rossana Rosso, Elisabetta Romagnoli, Natalia Raejentroph, Alessandro Ragno, Massimiliano Celi, Jessica Pepe, Emilio D’Erasmo, and Salvatore Minisola

Biomarkers of Bone Turnover after a Short Period of Steroid Therapy in Elderly Men
Clin Chem 2001 47: 1314-1316. [Extract] [Full Text] [PDF]  

Daniel C. French, Michael Saltzgueber, David R. Hicks, Annabel L. Cowper, and David W. Holt

HPLC Assay with Ultraviolet Detection for Therapeutic Drug Monitoring of Sirolimus
Clin Chem 2001 47: 1316-1319. [Extract] [Full Text] [PDF]  

Hubert A. Carchon and Jaak Jaeken

Determination of D-Mannose in Serum by Capillary Electrophoresis
Clin Chem 2001 47: 1319-1321. [Extract] [Full Text] [PDF]  

Valérie Serru, Bruno Baudin, Frédéric Ziegler, Jean-Philippe David, Marie-Josèphe Cals, Michel Vaubourdolle, and Nathalie Mario

Quantification of Reduced and Oxidized Glutathione in Whole Blood Samples by Capillary Electrophoresis
Clin Chem 2001 47: 1321-1324. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Zong-Mei Sheng, Ronald M. Przygodzki, and Timothy J. O’Leary

Rapid Screening for KIT Mutations by Capillary Electrophoresis
Clin Chem 2001 47: 1325-1326. [Extract] [Full Text] [PDF]  

David F. Keren, Ronald Gulbranson, John L. Carey, and John C. Krauss

2-Mercaptoethanol Treatment Improves Measurement of an IgM M-Protein by Capillary Electrophoresis
Clin Chem 2001 47: 1326-1327. [Extract] [Full Text] [PDF]  

Xavier Fuentes-Arderiu

Influence Quantities and Uncertainty of Measurement
Clin Chem 2001 47: 1327-1328. [Extract] [Full Text] [PDF]  

Claudio Cavalli, Romolo M. Dorizzi, Marco Caputo, and Paolo Biban

Serendipitous Detection of Umbilical Venous Catheter Displacement by Cardiac Troponin I Measurement
Clin Chem 2001 47: 1328-1329. [Extract] [Full Text] [PDF]  

Jan S. Krouwer

How to Improve Total Error Modeling by Accounting for Error Sources Beyond Imprecision and Bias
Clin Chem 2001 47: 1329-1330. [Extract] [Full Text] [PDF]  

James C. Boyd and David E. Bruns

Drs. Boyd and Bruns respond:
Clin Chem 2001 47: 1330-1331. [Extract] [Full Text] [PDF]  

Nicolas von Ahsen, Michael Oellerich, and Ekkehard Schütz

Limitations of Genotyping Based on Amplicon Melting Temperature
Clin Chem 2001 47: 1331-1332. [Extract] [Full Text] [PDF]  

Stephen A. Butler and Laurence A. Cole

Use of Heterophilic Antibody Blocking Agent (HBT) in Reducing False-Positive hCG Results
Clin Chem 2001 47: 1332-1333. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Denis C. Lehotay

Amino Acid Analysis Protocols. Catherine Cooper, Nicolle Packer, and Keith Williams, eds. Totowa, NJ: Humana Press, 2001, 265 pp., $84.50. ISBN 0-89603-656-1.
Clin Chem 2001 47: 1334. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2001 47: 1335-1342. [Extract] [Full Text] [PDF]  

Accent:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2001 47: 1343-1344. [Extract] [Full Text] [PDF]  

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