Editorials:

Christopher P. Price

Microarrays: The Reincarnation of Multiplexing in Laboratory Medicine, But Now More Relevant?
Clin Chem 2001 47: 1345-1346. [Extract] [Full Text] [PDF]  

Michael Kleerekoper

Biochemical Markers of Bone Turnover: Why Theory, Research, and Clinical Practice Are Still in Conflict
Clin Chem 2001 47: 1347-1349. [Extract] [Full Text] [PDF]  

Special Reports:

Jae K. Lee

Analysis Issues for Gene Expression Array Data
Clin Chem 2001 47: 1350-1352. [Extract] [Full Text] [PDF]  

Reviews:

John E.M. Midgley

Direct and Indirect Free Thyroxine Assay Methods: Theory and Practice
Clin Chem 2001 47: 1353-1363. [Abstract] [Full Text] [PDF] Appendix  

Molecular Diagnostics and Genetics:

Ulrich Glümer Jensen, Niels Jacob Brandt, Ernst Christensen, Flemming Skovby, Bent Nørgaard-Pedersen, and Henrik Simonsen

Neonatal Screening for Galactosemia by Quantitative Analysis of Hexose Monophosphates Using Tandem Mass Spectrometry: A Retrospective Study
Clin Chem 2001 47: 1364-1372. [Abstract] [Full Text] [PDF]  

Tony M. Hsu, Scott M. Law, Shenghui Duan, Bruce P. Neri, and Pui-Yan Kwok

Genotyping Single-Nucleotide Polymorphisms by the Invader Assay with Dual-Color Fluorescence Polarization Detection
Clin Chem 2001 47: 1373-1377. [Abstract] [Full Text] [PDF]  

Kandiah Umapathysivam, John J. Hopwood, and Peter J. Meikle

Determination of Acid -Glucosidase Activity in Blood Spots as a Diagnostic Test for Pompe Disease
Clin Chem 2001 47: 1378-1383. [Abstract] [Full Text] [PDF]  

Mark S. Turner, Sarah Penning, Angela Sharp, Valentine J. Hyland, Ray Harris, C. Phillip Morris, and Angela van Daal

Solid-Phase Amplification for Detection of C282Y and H63D Hemochromatosis (HFE) Gene Mutations
Clin Chem 2001 47: 1384-1389. [Abstract] [Full Text] [PDF]  

Lars Allan Larsen, Paal Skytt Andersen, Jørgen Kanters, Ida Hastrup Svendsen, Joes Ramsøe Jacobsen, Jens Vuust, Göran Wettrell, Lisbeth Tranebjærg, Jørn Bathen, and Michael Christiansen

Screening for Mutations and Polymorphisms in the Genes KCNH2 and KCNE2 Encoding the Cardiac HERG/MiRP1 Ion Channel: Implications for Acquired and Congenital Long Q-T Syndrome
Clin Chem 2001 47: 1390-1395. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

Anne-Mette Hvas, Jørgen Ellegaard, and Ebba Nexø

Vitamin B₁₂ Treatment Normalizes Metabolic Markers But Has Limited Clinical Effect: A Randomized Placebo-controlled Study
Clin Chem 2001 47: 1396-1404. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Bruno Cassinat, Diane Darsin, Philippe Guardiola, Marie-Elisabeth Toubert, Jean-Didier Rain, Eliane Gluckman, and Marie-Hélène Schlageter

Intermethod Discordance for -Fetoprotein Measurements in Fanconi Anemia
Clin Chem 2001 47: 1405-1409. [Abstract] [Full Text] [PDF]  

Reiko Okabe, Kiyoshi Nakatsuka, Masaaki Inaba, Takami Miki, Hiroshi Naka, Hideki Masaki, Atushi Moriguchi, and Yoshiki Nishizawa

Clinical Evaluation of the Elecsys ß-CrossLaps Serum Assay, a New Assay for Degradation Products of Type I Collagen C-Telopeptides
Clin Chem 2001 47: 1410-1414. [Abstract] [Full Text] [PDF]  

Pauliina Nurmikko, Kim Pettersson, Timo Piironen, Jonas Hugosson, and Hans Lilja

Discrimination of Prostate Cancer from Benign Disease by Plasma Measurement of Intact, Free Prostate-specific Antigen Lacking an Internal Cleavage Site at Lys¹⁴⁵-Lys¹⁴⁶
Clin Chem 2001 47: 1415-1423. [Abstract] [Full Text] [PDF]  

Andreas Schulze, David Frommhold, Georg F. Hoffmann, and Ertan Mayatepek

Spectrophotometric Microassay for -Aminolevulinate Dehydratase in Dried-Blood Spots as Confirmation for Hereditary Tyrosinemia Type I
Clin Chem 2001 47: 1424-1429. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Michelle C. McKinley, J.J. Strain, Joseph McPartlin, John M. Scott, and Helene McNulty

Plasma Homocysteine Is Not Subject to Seasonal Variation
Clin Chem 2001 47: 1430-1436. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Thomas E. Mürdter, Janet Coller, Alexander Claviez, Frank Schönberger, Ute Hofmann, Peter Dreger, and Matthias Schwab

Sensitive and Rapid Quantification of Busulfan in Small Plasma Volumes by Liquid Chromatography–Electrospray Mass Spectrometry
Clin Chem 2001 47: 1437-1442. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Markus J. Seibel, Matthias Lang, and Wolf-Jochen Geilenkeuser

Interlaboratory Variation of Biochemical Markers of Bone Turnover
Clin Chem 2001 47: 1443-1450. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Rick Wiese, Yuri Belosludtsev, Tom Powdrill, Patricia Thompson, and Mike Hogan

Simultaneous Multianalyte ELISA Performed on a Microarray Platform
Clin Chem 2001 47: 1451-1457. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Zhang Hong, Zhang Xinding, Zhang Tianlin, and Chen Liren

Excitatory Amino Acids in Cerebrospinal Fluid of Patients with Acute Head Injuries
Clin Chem 2001 47: 1458-1462. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Sam A. Margolis and Edward Park

Stability of Ascorbic Acid in Solutions Stored in Autosampler Vials
Clin Chem 2001 47: 1463-1464. [Extract] [Full Text] [PDF]  

Glenn Van den Bosch, Jan Van den Bossche, Carola Wagner, Pieter De Schouwer, Martine Van De Vyvere, and Hugo Neels

Determination of Iron Metabolism-related Reference Values in a Healthy Adult Population
Clin Chem 2001 47: 1465-1467. [Extract] [Full Text] [PDF]  

Anna Pastore, Fiorella Piemonte, Mattia Locatelli, Anna Lo Russo, Laura Maria Gaeta, Giulia Tozzi, and Giorgio Federici

Determination of Blood Total, Reduced, and Oxidized Glutathione in Pediatric Subjects
Clin Chem 2001 47: 1467-1469. [Extract] [Full Text] [PDF]  

András Guttman, Hong-Guang Gao, and Richard Haas

Rapid Analysis of Mitochondrial DNA Heteroplasmy in Diabetes by Gel-Microchip Electrophoresis
Clin Chem 2001 47: 1469-1472. [Extract] [Full Text] [PDF]  

Axel Semjonow, Frank Oberpenning, Christoph Weining, Manuel Schön, Burkhard Brandt, Gabriela De Angelis, Achim Heinecke, Michael Hamm, Petra Stieber, Lothar Hertle, and Hans-Peter Schmid

Do Modifications of Nonequimolar Assays for Total Prostate-specific Antigen Improve Detection of Prostate Cancer?
Clin Chem 2001 47: 1472-1475. [Extract] [Full Text] [PDF]  

Daisuke Furuya, Reiko Kaneko, Atsuhito Yagihashi, Teruo Endoh, Tomomi Yajima, Daisuke Kobayashi, Kazuki Yano, Eisuke Tsuda, and Naoki Watanabe

Immuno-PCR Assay for Homodimeric Osteoprotegerin
Clin Chem 2001 47: 1475-1477. [Extract] [Full Text] [PDF]  

Xavier Bossuyt and Godelieve Mariën

False-Negative Results in Detection of Monoclonal Proteins by Capillary Zone Electrophoresis: A Prospective Study
Clin Chem 2001 47: 1477-1479. [Extract] [Full Text] [PDF]  

Larry J. Kricka and Paolo Fortina

Microarray Technology and Applications: An All-Language Literature Survey Including Books and Patents
Clin Chem 2001 47: 1479-1482. [Extract] [Full Text] [PDF] Supplemental Data  

Helen Stowe, David Lawrence, David J. Newman, and Edmund J. Lamb

Analytical Performance of a Particle-enhanced Nephelometric Immunoassay for Serum Cystatin C Using Rate Analysis
Clin Chem 2001 47: 1482-1485. [Extract] [Full Text] [PDF]  

Maria Shipkova, Victor William Armstrong, Michael G. Kiehl, Paul Dieter Niedmann, Ekkehard Schütz, Michael Oellerich, and Eberhard Wieland

Quantification of Mycophenolic Acid in Plasma Samples Collected during and Immediately after Intravenous Administration of Mycophenolate Mofetil
Clin Chem 2001 47: 1485-1488. [Extract] [Full Text] [PDF]  

Dirk O. Hasselmann, Gunter Rappl, Wolfgang Tilgen, and Uwe Reinhold

Extracellular Tyrosinase mRNA within Apoptotic Bodies Is Protected from Degradation in Human Serum
Clin Chem 2001 47: 1488-1489. [Extract] [Full Text] [PDF]  

Case Report:

Valérie Canva, Sandrine Piotte, Jean-Pierre Aubert, Nicole Porchet, Martine Lecomte-Houcke, Guillemette Huet, Tahar Zenjari, Didier Roumilhac, François-René Pruvot, Pierre Degand, Jean-Claude Paris, and Malika Balduyck

Heterozygous M3Mmalton ₁-Antitrypsin Deficiency Associated with End-Stage Liver Disease: Case Report and Review
Clin Chem 2001 47: 1490-1496. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Pierre D. Delmas

Standardization of Bone Marker Nomenclature
Clin Chem 2001 47: 1497. [Extract] [Full Text] [PDF]  

Gianvico Melzi d’Eril, Adriano Anesi, Marcello Maggiore, and Valerio Leoni

Biological Variation of Serum Amyloid A in Healthy Subjects
Clin Chem 2001 47: 1498-1499. [Extract] [Full Text] [PDF]  

Leila Edno-Mcheik, Jean-Michel Gaulier, Isabella Combourieu, Eric Lacassie, and Amir Hadzic

Heptaminol Interferes in the AxSYM FPIA Amphetamine/Methamphetamine II Assay
Clin Chem 2001 47: 1499-1500. [Extract] [Full Text] [PDF]  

Maria-Cristina Belardinelli, Allel Chabli, Bernadette Chadefaux-Vekemans, and Pierre Kamoun

Urinary Sulfur Compounds in Down Syndrome
Clin Chem 2001 47: 1500-1501. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Steven W. Graves

Methods in Molecular Medicine: Angiotensin Protocols. Donna H. Wang, ed. Totowa, NJ: Humana Press, 2001, 530 pp., $135.00, hard cover. ISBN 0-89603-763-0.
Clin Chem 2001 47: 1502. [Extract] [Full Text] [PDF]  

Theodore E. Mifflin

Molecular Diagnosis. S. Jeffrey, J. Booth, and S. Myint. Oxford, UK: BIOS Scientific Publishers, 2000, 124 pp., $36.95. ISBN 0-387-915-11-7.
Clin Chem 2001 47: 1502-1503. [Extract] [Full Text] [PDF]  

Laurie E. Cohen

Human Growth Hormone: Research and Clinical Practice. Roy G. Smith and Michael O. Thorner, eds. Totowa, NJ: Humana Press Inc., 2000, 348 pp., $135.00, hardcover. ISBN 0-89603-505-0.
Clin Chem 2001 47: 1503-1504. [Extract] [Full Text] [PDF]  

Christopher S. Frings

Clinical Laboratory Management: Leadership Principles for the 21st Century. Donna L. Nigon. New York, NY: McGraw-Hill, 2000, 325 pp., $49.00. ISBN 0-07-047182-7.
Clin Chem 2001 47: 1504. [Extract] [Full Text] [PDF]  

Kathryn Tarentino

Medicinal Plants of the World, Volume 2. Chemical Constituents, Traditional and Modern Medicinal Uses. Ivan A. Ross. Totowa, NJ: Humana Press, 2001, 488 pp., $99.50. ISBN 0-896-03877-7.
Clin Chem 2001 47: 1504-1505. [Extract] [Full Text] [PDF]  

Correction:

M.A. Mansoor, C. Bergmark, S.J. Haswell, I.F. Savage, P.H. Evans, R.K. Berge, A.M. Svardal, and O. Kristensen

Erratum
Clin Chem 2001 47: 1505. [Extract] [Full Text] [PDF]  

Proceedings of the 24th Arnold O. Beckman Conference:

Ronald J. Elin

The Clinician and Laboratorian: Dynamic Transitions. The Twenty-Fourth Arnold O. Beckman Conference in Clinical Chemistry
Clin Chem 2001 47: 1507-1508. [Extract] [Full Text] [PDF]  

Robert M. Kisabeth

Laboratory Adaptations—Changing Expectations
Clin Chem 2001 47: 1509-1515. [Extract] [Full Text] [PDF]  

Matthew F. Emons

Integrated Patient Data for Optimal Patient Management: The Value of Laboratory Data in Quality Improvement
Clin Chem 2001 47: 1516-1520. [Abstract] [Full Text] [PDF]  

Raymond D. Aller

Connectivity from Source to Action
Clin Chem 2001 47: 1521-1525. [Abstract] [Full Text] [PDF]  

Bruce A. Friedman

The Total Laboratory Solution: A New Laboratory E-Business Model Based on a Vertical Laboratory Meta-Network
Clin Chem 2001 47: 1526-1535. [Abstract] [Full Text] [PDF]  

Matthew J. McQueen

Overview of Evidence-based Medicine: Challenges for Evidence-based Laboratory Medicine
Clin Chem 2001 47: 1536-1546. [Abstract] [Full Text] [PDF]  

David E. Bruns

Laboratory-related Outcomes in Healthcare
Clin Chem 2001 47: 1547-1552. [Abstract] [Full Text] [PDF]  

Karen L. Kaul

Molecular Detection of Mycobacterium tuberculosis: Impact on Patient Care
Clin Chem 2001 47: 1553-1558. [Abstract] [Full Text] [PDF]  

Violet A. Kelley and Angela M. Caliendo

Successful Testing Protocols in Virology
Clin Chem 2001 47: 1559-1562. [Abstract] [Full Text] [PDF]  

Joseph H. Keffer

Guidelines and Algorithms: Perceptions of Why and When They Are Successful and How to Improve Them
Clin Chem 2001 47: 1563-1572. [Abstract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2001 47: 1573-1574. [Extract] [Full Text] [PDF]  

Accent:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2001 47: 1575-1576. [Extract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.