Editorials:

Carl van Walraven

Practice Guidelines and Practicing Physicians—Who’s Guiding Whom?
Clin Chem 2002 48: 9-10. [Extract] [Full Text] [PDF]  

Special Reports:

G. Russell Warnick, Gary L. Myers, Gerald R. Cooper, and Nader Rifai

Impact of the Third Cholesterol Report from the Adult Treatment Panel of the National Cholesterol Education Program on the Clinical Laboratory
Clin Chem 2002 48: 11-17. [Abstract] [Full Text] [PDF]  

Minireview:

Jennifer L. Hess and W. Edward Highsmith, Jr

Telomerase Detection in Body Fluids
Clin Chem 2002 48: 18-24. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Nathalie Zammatteo, Laurence Lockman, Francis Brasseur, Etienne De Plaen, Christophe Lurquin, Pierre-Emmanuel Lobert, Sandrine Hamels, Thierry Boon, and José Remacle

DNA Microarray to Monitor the Expression of MAGE-A Genes
Clin Chem 2002 48: 25-34. [Abstract] [Full Text] [PDF]  

Leo L.M. Poon, Tse N. Leung, Tze K. Lau, Katherine C.K. Chow, and Y.M. Dennis Lo

Differential DNA Methylation between Fetus and Mother as a Strategy for Detecting Fetal DNA in Maternal Plasma
Clin Chem 2002 48: 35-41. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

Yuzuru Takemura, Haku Ishida, Yuji Inoue, and J. Robert Beck

Yield and Cost of Individual Common Diagnostic Tests in New Primary Care Outpatients in Japan
Clin Chem 2002 48: 42-54. [Abstract] [Full Text] [PDF]  

Marc A.M. van Wijk, Johan van der Lei, Mees Mosseveld, Arthur M. Bohnen, and Jan H. van Bemmel

Compliance of General Practitioners with a Guideline-based Decision Support System for Ordering Blood Tests
Clin Chem 2002 48: 55-60. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Thierry Dervieux, Yaqin Chu, Yi Su, Ching-Hon Pui, William E. Evans, and Mary V. Relling

HPLC Determination of Thiopurine Nucleosides and Nucleotides in Vivo in Lymphoblasts following Mercaptopurine Therapy
Clin Chem 2002 48: 61-68. [Abstract] [Full Text] [PDF]  

Brian G. Keevil, David P. Tierney, Donald P. Cooper, and Michael R. Morris

Rapid Liquid Chromatography-Tandem Mass Spectrometry Method for Routine Analysis of Cyclosporin A Over an Extended Concentration Range
Clin Chem 2002 48: 69-76. [Abstract] [Full Text] [PDF]  

Majed A. Refaai, Phan N. Nguyen, Thora S. Steffensen, Richard J. Evans, Joanne E. Cluette-Brown, and Michael Laposata

Liver and Adipose Tissue Fatty Acid Ethyl Esters Obtained at Autopsy Are Postmortem Markers for Premortem Ethanol Intake
Clin Chem 2002 48: 77-83. [Abstract] [Full Text] [PDF]  

Manfred Kollroser and Caroline Schober

Determination of Coumarin-type Anticoagulants in Human Plasma by HPLC-Electrospray Ionization Tandem Mass Spectrometry with an Ion Trap Detector
Clin Chem 2002 48: 84-91. [Abstract] [Full Text] [PDF]  

Kevin A. Francesconi, René Tanggaar, Christine J. McKenzie, and Walter Goessler

Arsenic Metabolites in Human Urine after Ingestion of an Arsenosugar
Clin Chem 2002 48: 92-101. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Catherine Massart and Didier Maugendre

Importance of the Detection Method for Thyroglobulin Antibodies for the Validity of Thyroglobulin Measurements in Sera from Patients with Graves Disease
Clin Chem 2002 48: 102-107. [Abstract] [Full Text] [PDF]  

Steen S. Holm, Lisbeth Andreasen, Steen H. Hansen, Jens Faber, and Poul Staun-Olsen

Influence of Adsorption and Deproteination on Potential Free Thyroxine Reference Methods
Clin Chem 2002 48: 108-114. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Sergei S. Likhodii, Kathy Musa, and Stephen C. Cunnane

Breath Acetone as a Measure of Systemic Ketosis Assessed in a Rat Model of the Ketogenic Diet
Clin Chem 2002 48: 115-120. [Abstract] [Full Text] [PDF]  

Letizia Mezzasoma, Tito Bacarese-Hamilton, Manlio Di Cristina, Ruggero Rossi, Francesco Bistoni, and Andrea Crisanti

Antigen Microarrays for Serodiagnosis of Infectious Diseases
Clin Chem 2002 48: 121-130. [Abstract] [Full Text] [PDF]  

Tina Rozaklis, Steven L. Ramsay, Phillip D. Whitfield, Enzo Ranieri, John J. Hopwood, and Peter J. Meikle

Determination of Oligosaccharides in Pompe Disease by Electrospray Ionization Tandem Mass Spectrometry
Clin Chem 2002 48: 131-139. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Donald S. Young, Bruce S. Sachais, and Leigh C. Jefferies

Effect of Disease Complications on Hospital Costs
Clin Chem 2002 48: 140-149. [Abstract] [Full Text] [PDF] Supplemental Tables  

Donald S. Young, Bruce S. Sachais, and Leigh C. Jefferies

Comparative Costs of Treating Adults and Children within Selected Diagnosis-related Groups
Clin Chem 2002 48: 150-160. [Abstract] [Full Text] [PDF] Supplemental Tables  

General Clinical Chemistry:

Gordon Siek, Joseph Lawlor, Donna Pelczar, Meena Sane, and Joseph Musto

Direct Serum Total Iron-binding Capacity Assay Suitable for Automated Analyzers
Clin Chem 2002 48: 161-166. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Sophie Richard, Véronique Miossec, Jean-François Moreau, and Jean-Luc Taupin

Detection of Oligoclonal Immunoglobulins in Cerebrospinal Fluid by an Immunofixation-Peroxidase Method
Clin Chem 2002 48: 167-173. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Simona Pichini, Mònica Navarro, Magí Farré, Jordi Ortuño, Pere Nolasc Roset, Roberta Pacifici, Piergiorgio Zuccaro, Jordi Segura, and Rafael de la Torre

On-Site Testing of 3,4-Methylenedioxymethamphetamine (Ecstasy) in Saliva with Drugwipe and Drugread: A Controlled Study in Recreational Users
Clin Chem 2002 48: 174-176. [Extract] [Full Text] [PDF]  

Patricia M. Jones, Susan Tjoa, Paul V. Fennessey, Stephen I. Goodman, and Michael J. Bennett

Addition of Quantitative 3-Hydroxy-Octadecanoic Acid to the Stable Isotope Gas Chromatography-Mass Spectrometry Method for Measuring 3-Hydroxy Fatty Acids
Clin Chem 2002 48: 176-179. [Extract] [Full Text] [PDF]  

Burcu Meric, Nazife Kilicaslan, Kagan Kerman, Dilsat Ozkan, Umran Kurun, Nejat Aksu, and Mehmet Ozsoz

Performance of Precision G Blood Glucose Analyzer with a New Test Strip G2b on Neonatal Samples
Clin Chem 2002 48: 179-180. [Extract] [Full Text] [PDF]  

Junji Kato, Masayoshi Kobune, Yutaka Kohgo, Koshi Fujikawa, Rishu Takimoto, Yoshihiro Torimoto, Yoshihisa Ito, Masami Bessho, Tomomitsu Hotta, Akihisa Hikawa, Takafumi Fujii, Kari Punnonen, and Yoshiro Niitsu

Ratio of Transferrin (Tf) to Tf-Receptor Complex in Circulation Differs Depending on Tf Iron Saturation
Clin Chem 2002 48: 181-183. [Extract] [Full Text] [PDF]  

Natàlia Ferré, Frederic Gómez, Jordi Camps, Josep M. Simó, Michelle M. Murphy, Joan Fernández-Ballart, and Jorge Joven

Plasma Homocysteine Concentrations in Patients with Liver Cirrhosis
Clin Chem 2002 48: 183-185. [Extract] [Full Text] [PDF]  

History:

Louis Rosenfeld

Clinical Chemistry Since 1800: Growth and Development
Clin Chem 2002 48: 186-197. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Guy P. Armstrong, Antony N. Barker, Hitesh Patel, and Hamish H. Hart

Reference Interval for Troponin I on the ACS:Centaur Assay: A Recommendation Based on the Recent Redefinition of Myocardial Infarction
Clin Chem 2002 48: 198-199. [Extract] [Full Text] [PDF]  

Siegfried Burggraf, Siegfried Kösel, Sabine Lohmann, Reinhard Beck, and Bernhard Olgemöller

Unexplained DNA Melting Behavior in a Genotyping Assay
Clin Chem 2002 48: 199-201. [Extract] [Full Text] [PDF]  

Graham H. White, Philip A. Tideman, Dieter Mangold, and Rainer Zerback

Heterophilic Antibody Interference with CARDIAC T Quantitative Rapid Assay • Representatives of Roche Diagnostics respond:
Clin Chem 2002 48: 201-203. [Extract] [Full Text] [PDF]  

Rose Daher, Joud H. Haidar, and Hadi Al-Amin

Rifampin Interference with Opiate Immunoassays
Clin Chem 2002 48: 203-204. [Extract] [Full Text] [PDF]  

Xavier Bossuyt and Willy E. Peetermans

Effect of Piperacillin-Tazobactam on Clinical Capillary Zone Electrophoresis of Serum Proteins
Clin Chem 2002 48: 204-205. [Extract] [Full Text] [PDF]  

Angelique Gagajewski, Gershwin K. Davis, Julie Kloss, Gregory K. Poch, Cynthia J. Anderson, and Fred S. Apple

False-Positive Lysergic Acid Diethylamide Immunoassay Screen Associated with Fentanyl Medication
Clin Chem 2002 48: 205-206. [Extract] [Full Text] [PDF]  

Hershel Raff, Peter J. Homar, and Edith A. Burns

Comparison of Two Methods for Measuring Salivary Cortisol
Clin Chem 2002 48: 207-208. [Extract] [Full Text] [PDF]  

Franco Tagliaro, Federica Bortolotti, Romolo M. Dorizzi, Mario Marigo, Joris R. Delanghe, Birgitte Wuyts, and Marc L. De Buyzere

Caveats in Carbohydrate-deficient Transferrin Determination • Drs. Delanghe, Wuyts, and De Buyzere respond:
Clin Chem 2002 48: 208-209. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Thomas W. Prior

Muscular Dystrophy: Methods and Protocols. Katherine M.D. Bushby and Louise V.B. Anderson, eds. Totowa, NJ: Humana Press, 2001, 436 pp., $99.50, hardcover. ISBN 0-89603-695-2.
Clin Chem 2002 48: 210-211. [Extract] [Full Text] [PDF]  

Thomas P. Moyer

Brush with Death: A Social History of Lead Poisoning. Christian Warren. Baltimore, MD: The Johns Hopkins University Press, 2000, 370 pp., $45.00, hardcover. ISBN 0-8018-6289-2.
Clin Chem 2002 48: 210. [Extract] [Full Text] [PDF]  

Theodore E. Mifflin

DNA Microarrays: A Practical Approach. Mark Schena, ed. Oxford: Oxford University Press, 1999, 209 pp., $55.00, paperback. ISBN 0-19-963777-8. Microarray Biochip Technology. Mark Schena, ed. Natick, MA: Eaton Publishing, 2000, 298 pp., $45.95. ISBN 1-881299-37-6. DNA Arrays: Methods and Protocols. Jang B. Rampal, ed. Totowa, NJ: Humana Press, 2001, 264 pp., $89.50. ISBN 0-89603-822-X.
Clin Chem 2002 48: 211-213. [Extract] [Full Text] [PDF]  

Oswald Sonntag

Tietz Fundamentals of Clinical Chemistry, Fifth Edition. Carl A. Burtis and Edward R. Ashwood, eds. Philadelphia: WB Saunders, 2001, 1091 pp., $75.00. ISBN 0-7216-8634-6.
Clin Chem 2002 48: 213. [Extract] [Full Text] [PDF]  

Correction:

Correction for vol. 47, p. 1974
Clin Chem 2002 48: 213. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2002 48: 214. [Extract] [Full Text] [PDF]  

Accent^®:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2002 48: 215-216. [Extract] [Full Text] [PDF]  

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