Editorials:

Robert Star, Thomas Hostetter, and Glen L. Hortin

New Markers for Kidney Disease
Clin Chem 2002 48: 1375-1376. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Werner Koch, Wolfgang Latz, Marianne Eichinger, Ariel Roguin, Andrew P. Levy, Albert Schömig, and Adnan Kastrati

Genotyping of the Common Haptoglobin Hp 1/2 Polymorphism Based on PCR
Clin Chem 2002 48: 1377-1382. [Abstract] [Full Text] [PDF]  

Karin J.A. Lievers, Lydia A. Afman, Leo A.J. Kluijtmans, Godfried H.J. Boers, Petra Verhoef, Martin den Heijer, Frans J.M. Trijbels, and Henk J. Blom

Polymorphisms in the Transcobalamin Gene: Association with Plasma Homocysteine in Healthy Individuals and Vascular Disease Patients
Clin Chem 2002 48: 1383-1389. [Abstract] [Full Text] [PDF]  

Fredoen Valianpour, Ronald J.A. Wanders, Peter G. Barth, Henk Overmars, and Albert H. van Gennip

Quantitative and Compositional Study of Cardiolipin in Platelets by Electrospray Ionization Mass Spectrometry: Application for the Identification of Barth Syndrome Patients
Clin Chem 2002 48: 1390-1397. [Abstract] [Full Text] [PDF]  

Niels Wedemeyer, Thomas Pötter, Steffi Wetzlich, and Wolfgang Göhde

Flow Cytometric Quantification of Competitive Reverse Transcription-PCR Products
Clin Chem 2002 48: 1398-1405. [Abstract] [Full Text] [PDF]  

Jess G. Evans and Cindy Lee-Tataseo

Determination of the Factor V Leiden Single-Nucleotide Polymorphism in a Commercial Clinical Laboratory by Use of NanoChip Microelectronic Array Technology
Clin Chem 2002 48: 1406-1411. [Abstract] [Full Text] [PDF]  

Ulrike M. Stamer, Bettina Bayerer, Stephanie Wolf, Andreas Hoeft, and Frank Stüber

Rapid and Reliable Method for Cytochrome P450 2D6 Genotyping
Clin Chem 2002 48: 1412-1417. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Thomas Krauss, Günter Emons, Walther Kuhn, and Hellmut G. Augustin

Predictive Value of Routine Circulating Soluble Endothelial Cell Adhesion Molecule Measurements during Pregnancy
Clin Chem 2002 48: 1418-1425. [Abstract] [Full Text] [PDF]  

John B. Whitfield, Gu Zhu, John E. Nestler, Andrew C. Heath, and Nicholas G. Martin

Genetic Covariation between Serum -Glutamyltransferase Activity and Cardiovascular Risk Factors
Clin Chem 2002 48: 1426-1431. [Abstract] [Full Text] [PDF] Supplemental Data  

Mauro Panteghini, Claudio Cuccia, Graziella Bonetti, Raffaele Giubbini, Franca Pagani, and Elena Bonini

Single-Point Cardiac Troponin T at Coronary Care Unit Discharge after Myocardial Infarction Correlates with Infarct Size and Ejection Fraction
Clin Chem 2002 48: 1432-1436. [Abstract] [Full Text] [PDF]  

Jerry A. Katzmann, Raynell J. Clark, Roshini S. Abraham, Sandra Bryant, James F. Lymp, Arthur R. Bradwell, and Robert A. Kyle

Serum Reference Intervals and Diagnostic Ranges for Free and Free Immunoglobulin Light Chains: Relative Sensitivity for Detection of Monoclonal Light Chains
Clin Chem 2002 48: 1437-1444. [Abstract] [Full Text] [PDF]  

Hiroshi Oda, Yasuhiko Shiina, Kousuke Seiki, Nobuyuki Sato, Naomi Eguchi, and Yoshihiro Urade

Development and Evaluation of a Practical ELISA for Human Urinary Lipocalin-Type Prostaglandin D Synthase
Clin Chem 2002 48: 1445-1453. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Masashi Akaike, Hiroyuki Azuma, Ayako Kagawa, Kazuya Matsumoto, Ikuro Hayashi, Katsuya Tamura, Takeshi Nishiuchi, Takahiko Iuchi, Nobuyuki Takamori, Ken-ichi Aihara, Tomonori Yoshida, Yasuhiko Kanagawa, and Toshio Matsumoto

Effect of Aspirin Treatment on Serum Concentrations of Lipoprotein(a) in Patients with Atherosclerotic Diseases
Clin Chem 2002 48: 1454-1459. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Thomas P. Moyer, Joel R. Charlson, Robert J. Enger, Lowell C. Dale, Jon O. Ebbert, Darrell R. Schroeder, and Richard D. Hurt

Simultaneous Analysis of Nicotine, Nicotine Metabolites, and Tobacco Alkaloids in Serum or Urine by Tandem Mass Spectrometry, with Clinically Relevant Metabolic Profiles
Clin Chem 2002 48: 1460-1471. [Abstract] [Full Text] [PDF]  

Frank T. Peters, Thomas Kraemer, and Hans H. Maurer

Drug Testing in Blood: Validated Negative-Ion Chemical Ionization Gas Chromatographic–Mass Spectrometric Assay for Determination of Amphetamine and Methamphetamine Enantiomers and Its Application to Toxicology Cases
Clin Chem 2002 48: 1472-1485. [Abstract] [Full Text] [PDF]  

Insook Kim, Allan J. Barnes, Jonathan M. Oyler, Raf Schepers, Robert E. Joseph, Jr, Edward J. Cone, Diana Lafko, Eric T. Moolchan, and Marilyn A. Huestis

Plasma and Oral Fluid Pharmacokinetics and Pharmacodynamics after Oral Codeine Administration
Clin Chem 2002 48: 1486-1496. [Abstract] [Full Text] [PDF]  

Tomasz Pawinski, Mike Hale, Magda Korecka, William E. Fitzsimmons, and Leslie M. Shaw

Limited Sampling Strategy for the Estimation of Mycophenolic Acid Area under the Curve in Adult Renal Transplant Patients Treated with Concomitant Tacrolimus
Clin Chem 2002 48: 1497-1504. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Giovanni Vitale, Antonio Ciccarelli, Michele Caraglia, Maurizio Galderisi, Riccardo Rossi, Salvatore Del Prete, Alberto Abbruzzese, and Giovanni Lupoli

Comparison of Two Provocative Tests for Calcitonin in Medullary Thyroid Carcinoma: Omeprazole vs Pentagastrin
Clin Chem 2002 48: 1505-1510. [Abstract] [Full Text] [PDF]  

Robert L. Taylor, Dwaine Machacek, and Ravinder J. Singh

Validation of a High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Method for Urinary Cortisol and Cortisone
Clin Chem 2002 48: 1511-1519. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Henk Baadenhuijsen, Herman Steigstra, Christa Cobbaert, Aldy Kuypers, Cas Weykamp, and Rob Jansen

Commutability Assessment of Potential Reference Materials Using a Multicenter Split-Patient-Sample Between-Field-Methods (Twin-Study) Design: Study within the Framework of the Dutch Project "Calibration 2000"
Clin Chem 2002 48: 1520-1525. [Abstract] [Full Text] [PDF]  

Christa Cobbaert, Cas Weykamp, Henk Baadenhuijsen, Aldy Kuypers, Jan Lindemans, and Rob Jansen

Selection, Preparation, and Characterization of Commutable Frozen Human Serum Pools as Potential Secondary Reference Materials for Lipid and Apolipoprotein Measurements: Study within the Framework of the Dutch Project "Calibration 2000"
Clin Chem 2002 48: 1526-1538. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Naomi Q. Hanson, John H. Eckfeldt, Kerry Schwichtenberg, Ömer Aras, and Michael Y. Tsai

Interlaboratory Variation of Plasma Total Homocysteine Measurements: Results of Three Successive Homocysteine Proficiency Testing Surveys
Clin Chem 2002 48: 1539-1545. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Antonio Carroccio, Giustina Vitale, Lidia Di Prima, Nadia Chifari, Salvatore Napoli, Cristina La Russa, Gaspare Gulotta, Maurizio R. Averna, Giuseppe Montalto, Serafino Mansueto, and Alberto Notarbartolo

Comparison of Anti-Transglutaminase ELISAs and an Anti-Endomysial Antibody Assay in the Diagnosis of Celiac Disease: A Prospective Study
Clin Chem 2002 48: 1546-1550. [Abstract] [Full Text] [PDF]  

Akira Takahashi, Yoshiaki Iwasaki, Jiro Miyaike, Hideaki Taniguchi, Hiroyuki Shimomura, Tadashi Hanafusa, Yasuhiro Yumoto, Akio Moriya, Norio Koide, and Takao Tsuji

Quantitative Analysis of p40/p46 and p69/p71 Forms of 2',5'-Oligoadenylate Synthetase mRNA by Competitive PCR and Its Clinical Application
Clin Chem 2002 48: 1551-1559. [Abstract] [Full Text] [PDF]  

Nutrition:

Qinghong Han, Mingxu Xu, Li Tang, Xuezhong Tan, Xiuying Tan, Yuying Tan, and Robert M. Hoffman

Homogeneous, Nonradioactive, Enzymatic Assay for Plasma Pyridoxal 5-Phosphate
Clin Chem 2002 48: 1560-1564. [Abstract] [Full Text] [PDF]  

Hachiro Yamanishi, Shigeru Iyama, Yoshihisa Yamaguchi, Yuzuru Kanakura, and Yoshinori Iwatani

Modification of Fully Automated Total Iron-binding Capacity (TIBC) Assay in Serum and Comparison with Dimension TIBC Method
Clin Chem 2002 48: 1565-1570. [Abstract] [Full Text] [PDF]  

Steinar Hustad, Michelle C. McKinley, Helene McNulty, Jørn Schneede, J.J. Strain, John M. Scott, and Per Magne Ueland

Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Human Plasma and Erythrocytes at Baseline and after Low-Dose Riboflavin Supplementation
Clin Chem 2002 48: 1571-1577. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Marcel M. Verbeek, Herman P.M. de Reus, and Cas W. Weykamp

Comparison of Methods for the Detection of Oligoclonal IgG Bands in Cerebrospinal Fluid and Serum: Results of the Dutch Quality Control Survey
Clin Chem 2002 48: 1578-1580. [Extract] [Full Text] [PDF] Supplemental Data  

Gwendolyn A. McMillin, William E. Owen, Thomas L. Lambert, Barun K. De, Elizabeth L. Frank, Phillip R. Bach, Thomas M. Annesley, and William L. Roberts

Comparable Effects of DIGIBIND and DigiFab in Thirteen Digoxin Immunoassays
Clin Chem 2002 48: 1580-1584. [Extract] [Full Text] [PDF]  

Barry G. England, George H. Parsons, Russell M. Possley, Daniel S. McConnell, and A. Rees Midgley

Ultrasensitive Semiautomated Chemiluminescent Immunoassay for Estradiol
Clin Chem 2002 48: 1584-1586. [Extract] [Full Text] [PDF]  

Timo I. Takala, Pauli Suominen, Raimo Isoaho, Sirkka-Liisa Kivelä, Minna Löppönen, Olli Peltola, Allan Rajamäki, and Kerttu Irjala

Iron-Replete Reference Intervals to Increase Sensitivity of Hematologic and Iron Status Laboratory Tests in the Elderly
Clin Chem 2002 48: 1586-1589. [Extract] [Full Text] [PDF] Supplemental Data  

Guillaume Monneret, Nadia Elmenkouri, Julien Bohe, Anne-Lise Debard, Marie-Claude Gutowski, Jacques Bienvenu, and Alain Lepape

Analytical Requirements for Measuring Monocytic Human Lymphocyte Antigen DR by Flow Cytometry: Application to the Monitoring of Patients with Septic Shock
Clin Chem 2002 48: 1589-1592. [Extract] [Full Text] [PDF]  

Jürgen Borlak and Thomas Thum

Identification of Major CYP2C9 and CYP2C19 Polymorphisms by Fluorescence Resonance Energy Transfer Analysis
Clin Chem 2002 48: 1592-1594. [Extract] [Full Text] [PDF]  

Paola Luraschi, Simona Brambilla, Roberta Mozzi, Giampaolo Cattozzo, and Carlo Franzini

Monitoring Analytical Quality in Routine Glycohemoglobin Measurements
Clin Chem 2002 48: 1594-1597. [Extract] [Full Text] [PDF]  

Josep Ribalta, Lídia Figuera, Joan Fernández-Ballart, Elisabet Vilella, Manuel Castro Cabezas, Lluís Masana, and Jorge Joven

Newly Identified Apolipoprotein AV Gene Predisposes to High Plasma Triglycerides in Familial Combined Hyperlipidemia
Clin Chem 2002 48: 1597-1600. [Extract] [Full Text] [PDF]  

Godelieve Mariën, Els Oris, Arthur R. Bradwell, Norbert Blanckaert, and Xavier Bossuyt

Detection of Monoclonal Proteins in Sera by Capillary Zone Electrophoresis and Free Light Chain Measurements
Clin Chem 2002 48: 1600-1601. [Extract] [Full Text] [PDF]  

Helena Kuivaniemi, Sungpil Yoon, Hidenori Shibamura, Magdalena Skunca, Sompong Vongpunsawad, and Gerard Tromp

Primer-Extension Preamplified DNA Is a Reliable Template for Genotyping
Clin Chem 2002 48: 1601-1603. [Extract] [Full Text] [PDF]  

Pamela L. Drake, Edward Krieg, Alexander W. Teass, and Val Vallyathan

Two Assays for Urinary N-Acetyl-ß-D-glucosaminidase Compared
Clin Chem 2002 48: 1604-1605. [Extract] [Full Text] [PDF]  

Ke Xu, Robert H. Lipsky, Walid Mangal, Erica Ferro, and David Goldman

Single-Nucleotide Polymorphism Allele Frequencies Determined by Quantitative Kinetic Assay of Pooled DNA
Clin Chem 2002 48: 1605-1608. [Extract] [Full Text] [PDF]  

Sara Kim, Paul J. Henderson, Carla Phillips, Adam R. Orkand, Eric Maddox, Claudia Bien, Ann Smith, and Michael L. Astion

Web-based Competency Assessment System for Microscopic Urinalysis
Clin Chem 2002 48: 1608-1611. [Extract] [Full Text] [PDF] Supplemental Data  

Roger E.G. Schutgens, Fred J.L.M. Haas, Henk J.T. Ruven, Michael Spannagl, Klaus Horn, and Douwe H. Biesma

No Influence of Heparin Plasma and Other (Pre)analytic Variables on D-Dimer Determinations
Clin Chem 2002 48: 1611-1613. [Extract] [Full Text] [PDF]  

Kristin R. Fiebelkorn, Brenda G. Lee, Charles E. Hill, Angela M. Caliendo, and Frederick S. Nolte

Clinical Evaluation of an Automated Nucleic Acid Isolation System
Clin Chem 2002 48: 1613-1615. [Extract] [Full Text] [PDF] Supplemental Data  

Gisela Skopp, Lucia Pötsch, Rainer Mattern, and Rolf Aderjan

Short-Term Stability of Lysergic Acid Diethylamide (LSD), N-Desmethyl-LSD, and 2-Oxo-3-hydroxy-LSD in Urine, Assessed by Liquid Chromatography–Tandem Mass Spectrometry
Clin Chem 2002 48: 1615-1618. [Extract] [Full Text] [PDF]  

Tetsuro Kondo, Akihiko Sekizawa, Hiroshi Saito, Masatoshi Jimbo, Yumi Sugito, and Takashi Okai

Fate of Fetal Nucleated Erythrocytes Circulating in Maternal Blood: Apoptosis Is Induced by Maternal Oxygen Concentration
Clin Chem 2002 48: 1618-1620. [Extract] [Full Text] [PDF]  

Larry J. Kricka and Paolo Fortina

Microchips: An All-Language Literature Survey Including Books and Patents
Clin Chem 2002 48: 1620-1622. [Extract] [Full Text] [PDF] Supplemental Data  

Michele M. Flanders, Ronda Crist, Sekineh Safapour, and George M. Rodgers

Evaluation and Performance Characteristics of the STA-R Coagulation Analyzer
Clin Chem 2002 48: 1622-1624. [Extract] [Full Text] [PDF] Supplemental Data  

Letters to the Editor:

Daniel M. Hoefner and Kiang-Teck J. Yeo

Lot-to-Lot Inconsistency of Anticardiolipin Reagents
Clin Chem 2002 48: 1625-1626. [Extract] [Full Text] [PDF]  

Walter L. Binder and Brys Myers

Representatives of INOVA Diagnostics respond to the letter by Drs. Hoefner and Yeo:
Clin Chem 2002 48: 1626. [Extract] [Full Text] [PDF]  

Volkher Scharnhorst, Huib L. Vader, and Fedde van der Graaf

Characteristics of the Cardiac Troponin I Assay on the Immulite 2000 Analyzer
Clin Chem 2002 48: 1626-1627. [Extract] [Full Text] [PDF]  

Linda D. Youngman, Sarah Clark, Susan Manley, Richard Peto, and Rory Collins

Reliable Measurement of Glycated Hemoglobin in Frozen Blood Samples: Implications for Epidemiologic Studies
Clin Chem 2002 48: 1627-1629. [Extract] [Full Text] [PDF]  

Sheri M. Williams, Cindy A. Meadows, and Elaine Lyon

Automated DNA Extraction for Real-Time PCR
Clin Chem 2002 48: 1629-1630. [Extract] [Full Text] [PDF]  

Georg Schulthess, Peter Wiesli, and Friedrich E. Maly

Macrolide Treatment Does Not Influence Serum Homocysteine in Chlamydia pneumoniae-seropositive Patients Suffering from Atherosclerosis
Clin Chem 2002 48: 1631. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Fred D. Lasky

Performance-Driven Quality Control. Zoe C. Brooks. Washington, DC: AACC Press, 2001, 204 pp., $36.00 (members), $45.00 (nonmembers), soft cover. ISBN 1-890883-54-9.
Clin Chem 2002 48: 1632. [Extract] [Full Text] [PDF]  

Elaine Lyon

Methods in Molecular Biology, Volume 175. Genomics Protocols. Michael P. Starkey and Ramnath Elaswarapu, eds. Totowa, NJ: Humana Press, 2001, 538 pp., $125, hardcover. ISBN 0-89603-774-6.
Clin Chem 2002 48: 1632-1633. [Extract] [Full Text] [PDF]  

Corrections:

Correction
Clin Chem 2002 48: 1633. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2002 48: 1634-1636. [Extract] [Full Text] [PDF]  

Accent:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2002 48: 1637-1638. [Extract] [Full Text] [PDF]  

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