Editorials:

Isabelle Touitou

Standardized Testing for Mutations in Familial Mediterranean Fever
Clin Chem 2003 49: 1781-1782. [Extract] [Full Text] [PDF]  

Victor M. Montori and Gordon H. Guyatt

Summarizing Studies of Diagnostic Test Performance
Clin Chem 2003 49: 1783-1784. [Extract] [Full Text] [PDF]  

Special Reports:

Santica M. Marcovina, Marlys L. Koschinsky, John J. Albers, and Sonia Skarlatos

Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: Recent Advances and Future Directions
Clin Chem 2003 49: 1785-1796. [Abstract] [Full Text] [PDF]  

Reviews:

Donald H. Chace, Theodore A. Kalas, and Edwin W. Naylor

Use of Tandem Mass Spectrometry for Multianalyte Screening of Dried Blood Specimens from Newborns
Clin Chem 2003 49: 1797-1817. [Abstract] [Full Text] [PDF]  

Point/Counterpoint:

Jan S. Krouwer

Critique of the Guide to the Expression of Uncertainty in Measurement Method of Estimating and Reporting Uncertainty in Diagnostic Assays
Clin Chem 2003 49: 1818-1821. [Abstract] [Full Text] [PDF]  

Jesper Kristiansen

The Guide to Expression of Uncertainty in Measurement Approach for Estimating Uncertainty: An Appraisal
Clin Chem 2003 49: 1822-1829. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Filippo Carlucci, Antonella Tabucchi, Alessandro Aiuti, Francesca Rosi, Federica Floccari, Roberto Pagani, and Enrico Marinello

Capillary Electrophoresis in Diagnosis and Monitoring of Adenosine Deaminase Deficiency
Clin Chem 2003 49: 1830-1838. [Abstract] [Full Text] [PDF] Supplemental Data  

Suzan Wopereis, Stephanie Grünewald, Éva Morava, Johannes M. Penzien, Paz Briones, M. Teresa García-Silva, Pierre N.M. Demacker, Karin M.L.C. Huijben, and Ron A. Wevers

Apolipoprotein C-III Isofocusing in the Diagnosis of Genetic Defects in O-Glycan Biosynthesis
Clin Chem 2003 49: 1839-1845. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

Michael D. Brown, Joseph Lau, R. Darrell Nelson, and Jeffery A. Kline

Turbidimetric D-Dimer Test in the Diagnosis of Pulmonary Embolism: A Metaanalysis
Clin Chem 2003 49: 1846-1853. [Abstract] [Full Text] [PDF] Data Supplement  

Cancer Diagnostics:

Brahim Ramdani, Vincent Nuyens, Thierry Codden, Gael Perpete, Jacques Colicis, Anne Lenaerts, Jean-Pol Henry, and Franz J. Legros

Analyte Comigrating with Trisialotransferrin during Capillary Zone Electrophoresis of Sera from Patients with Cancer
Clin Chem 2003 49: 1854-1864. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Ian G. Davies, John M. Graham, and Bruce A. Griffin

Rapid Separation of LDL Subclasses by Iodixanol Gradient Ultracentrifugation
Clin Chem 2003 49: 1865-1872. [Abstract] [Full Text] [PDF]  

Jiri Frohlich and Milada Dobiásová

Fractional Esterification Rate of Cholesterol and Ratio of Triglycerides to HDL-Cholesterol Are Powerful Predictors of Positive Findings on Coronary Angiography
Clin Chem 2003 49: 1873-1880. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Anders Helander, Asgeir Husa, and Jan-Olof Jeppsson

Improved HPLC Method for Carbohydrate-deficient Transferrin in Serum
Clin Chem 2003 49: 1881-1890. [Abstract] [Full Text] [PDF]  

Olga Millán, Mercè Brunet, Josep M. Campistol, Ana Faura, Isabel Rojo, Elena Vidal, Olga Jiménez, Jordi Vives, Federic Oppenheimer, and Jaume Martorell

Pharmacodynamic Approach to Immunosuppressive Therapies Using Calcineurin Inhibitors and Mycophenolate Mofetil
Clin Chem 2003 49: 1891-1899. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Sylvain Poujol, Frédéric Pinguet, Françoise Malosse, Cécile Astre, Marc Ychou, Stéphane Culine, and Françoise Bressolle

Sensitive HPLC-Fluorescence Method for Irinotecan and Four Major Metabolites in Human Plasma and Saliva: Application to Pharmacokinetic Studies
Clin Chem 2003 49: 1900-1908. [Abstract] [Full Text] [PDF]  

Cécile Gay-Bellile, Djaouida Bengoufa, Pascal Houze, Didier Le Carrer, Mourad Benlakehal, Bernard Bousquet, Bernard Gourmel, and Thierry Le Bricon

Automated Multicapillary Electrophoresis for Analysis of Human Serum Proteins
Clin Chem 2003 49: 1909-1915. [Abstract] [Full Text] [PDF] Supplemental Data  

Andrew Kindness, Chandra N. Sekaran, and Jörg Feldmann

Two-Dimensional Mapping of Copper and Zinc in Liver Sections by Laser Ablation–Inductively Coupled Plasma Mass Spectrometry
Clin Chem 2003 49: 1916-1923. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Uwe Schauer, Frank Stemberg, Christian H.L. Rieger, Michael Borte, Simone Schubert, Frank Riedel, Udo Herz, Harald Renz, Manfred Wick, Hugh D. Carr-Smith, Arthur R. Bradwell, and Wilhelm Herzog

IgG Subclass Concentrations in Certified Reference Material 470 and Reference Values for Children and Adults Determined with The Binding Site Reagents
Clin Chem 2003 49: 1924-1929. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Pieter Schoen, Hilco Everts, Theo de Boer, and Wim van Oeveren

Serum Carnosinase Activity in Plasma and Serum: Validation of a Method and Values in Cardiopulmonary Bypass Surgery
Clin Chem 2003 49: 1930-1932. [Extract] [Full Text] [PDF]  

Peter Jatlow, Sherry McKee, and Stephanie S. O’Malley

Correction of Urine Cotinine Concentrations for Creatinine Excretion: Is It Useful?
Clin Chem 2003 49: 1932-1934. [Extract] [Full Text] [PDF]  

Sashka Hristoskova, Wolfgang Holzgreve, and Sinuhe Hahn

Fetal Nucleated Erythrocytes in Maternal Circulation Do Not Display a Classic Membrane-associated Apoptotic Characteristic (Phosphatidylserine Exposure) Despite Being Positive by Terminal dUTP Nuclear End Labeling
Clin Chem 2003 49: 1934-1937. [Extract] [Full Text] [PDF]  

Werner Koch, Wolfgang Latz, Marianne Eichinger, Claudia Gschwendner, Brita Teige, Albert Schömig, and Adnan Kastrati

Haptoglobin Gene Subtyping by Restriction Enzyme Analysis
Clin Chem 2003 49: 1937-1940. [Extract] [Full Text] [PDF] Supplemental Data  

Giorgio Ghilardi, Maria Luisa Biondi, Maddalena Erario, Emma Guagnellini, and Roberto Scorza

Colorectal Carcinoma Susceptibility and Metastases Are Associated with Matrix Metalloproteinase-7 Promoter Polymorphisms
Clin Chem 2003 49: 1940-1942. [Extract] [Full Text] [PDF]  

Dimitri Tchernitchko, Marie Legendre, Andrée Delahaye, Cécile Cazeneuve, Florence Niel, Michel Goossens, Serge Amselem, and Emmanuelle Girodon

Clinical Evaluation of a Reverse Hybridization Assay for the Molecular Detection of Twelve MEFV Gene Mutations
Clin Chem 2003 49: 1942-1945. [Extract] [Full Text] [PDF] Data Supplement  

Panagiotis Pantelidis, Michelle Lambert-Hammill, and Anthony S. Wierzbicki

Simple Sequence-specific-Primer-PCR Method To Identify the Three Main Apolipoprotein E Haplotypes
Clin Chem 2003 49: 1945-1948. [Extract] [Full Text] [PDF]  

Christian Oberkanins, Andreas Weinhäusel, Gernot Kriegshäuser, Anne Moritz, Fritz Kury, and Oskar A. Haas

Genetic Testing for Familial Mediterranean Fever in Austria by Means of Reverse-Hybridization Teststrips
Clin Chem 2003 49: 1948-1950. [Extract] [Full Text] [PDF]  

Jacques J. Willemsen, C.G.J. Sweep, Jacques W.M. Lenders, and H. Alec Ross

Stability of Plasma Free Metanephrines during Collection and Storage as Assessed by an Optimized HPLC Method with Electrochemical Detection
Clin Chem 2003 49: 1951-1953. [Extract] [Full Text] [PDF]  

Christine Stemmer, Michèle Beau-Faller, Erwan Pencreac’h, Eric Guerin, Anne Schneider, Didier Jaqmin, Elizabeth Quoix, Marie-Pierre Gaub, and Pierre Oudet

Use of Magnetic Beads for Plasma Cell-free DNA Extraction: Toward Automation of Plasma DNA Analysis for Molecular Diagnostics
Clin Chem 2003 49: 1953-1955. [Extract] [Full Text] [PDF] Supplemental Data  

Letters to the Editor:

Ferdinando Mannello, Francesca Luchetti, Barbara Canonico, and Stefano Papa

Effect of Anticoagulants and Cell Separation Media as Preanalytical Determinants on Zymographic Analysis of Plasma Matrix Metalloproteinases
Clin Chem 2003 49: 1956-1957. [Extract] [Full Text] [PDF]  

Graham P. Mead, Mark T. Drayson, Hugh D. Carr-Smith, and Arthur R. Bradwell

Measurement of Immunoglobulin Free Light Chains in Serum
Clin Chem 2003 49: 1957-1958. [Extract] [Full Text] [PDF]  

Jillian R. Tate, Peter Mollee, and Devinder Gill

Measurement of Immunoglobulin Free Light Chains in Serum: Response
Clin Chem 2003 49: 1958. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

A. Ralph Henderson

A Triptych of Statistics
Clin Chem 2003 49: 1959-1962. [Extract] [Full Text] [PDF]  

2003 San Diego Conference:

The San Diego Conference Cool Tools III: New Technologies for Molecular Diagnostics October 30–November 1, 2003
Clin Chem 2003 49: 1963-1967. [Extract] [Full Text] [PDF]  

Abstracts for CNAPS III:

Abstracts for CNAPS III
Clin Chem 2003 49: 1968. [Extract] [Full Text] [PDF] CNAPS III Abstracts  

The Clinical Chemist:

Clin Chem 2003 49: 1969-1970. [Extract] [Full Text] [PDF]  

Accent^®:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2003 49: 1971-1972. [Extract] [Full Text] [PDF]  

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