Editorials:

C. Sue Richards and Wayne W. Grody

Alternative Approaches to Proficiency Testing in Molecular Genetics
Clin Chem 2003 49: 717-718. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Rossa W.K. Chiu, Lisa Y.S. Chan, Nicole Y.L. Lam, Nancy B.Y. Tsui, Enders K.O. Ng, Timothy H. Rainer, and Y.M. Dennis Lo

Quantitative Analysis of Circulating Mitochondrial DNA in Plasma
Clin Chem 2003 49: 719-726. [Abstract] [Full Text] [PDF]  

Enders K.O. Ng, Tse N. Leung, Nancy B.Y. Tsui, Tze K. Lau, Nirmal S. Panesar, Rossa W.K. Chiu, and Y.M. Dennis Lo

The Concentration of Circulating Corticotropin-releasing Hormone mRNA in Maternal Plasma Is Increased in Preeclampsia
Clin Chem 2003 49: 727-731. [Abstract] [Full Text] [PDF]  

Maria Erali, Ben Schmidt, Elaine Lyon, and Carl Wittwer

Evaluation of Electronic Microarrays for Genotyping Factor V, Factor II, and MTHFR
Clin Chem 2003 49: 732-739. [Abstract] [Full Text] [PDF]  

Michael H.M. Chan, Kai Ming Chow, Anthony T.C. Chan, Chi Bon Leung, Lisa Y.S. Chan, Katherine C.K. Chow, Ching Wan Lam, and Y.M. Dennis Lo

Quantitative Analysis of Pleural Fluid Cell-free DNA as a Tool for the Classification of Pleural Effusions
Clin Chem 2003 49: 740-745. [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Shirley Hutchinson, Liu-Ying Luo, George M. Yousef, Antoninus Soosaipillai, and Eleftherios P. Diamandis

Purification of Human Kallikrein 6 from Biological Fluids and Identification of its Complex with ₁-Antichymotrypsin
Clin Chem 2003 49: 746-751. [Abstract] [Full Text] [PDF]  

Terence C.W. Poon, Tai-Tung Yip, Anthony T.C. Chan, Christine Yip, Victor Yip, Tony S.K. Mok, Conrad C.Y. Lee, Thomas W.T. Leung, Stephen K.W. Ho, and Philip J. Johnson

Comprehensive Proteomic Profiling Identifies Serum Proteomic Signatures for Detection of Hepatocellular Carcinoma and Its Subtypes
Clin Chem 2003 49: 752-760. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Angela Tammaro, Adele Bracco, Santolo Cozzolino, Maria Esposito, Antonietta Di Martino, Gennaro Savoia, Laura Zeuli, Giulio Piluso, Stefania Aurino, and Vincenzo Nigro

Scanning for Mutations of the Ryanodine Receptor (RYR1) Gene by Denaturing HPLC: Detection of Three Novel Malignant Hyperthermia Alleles
Clin Chem 2003 49: 761-768. [Abstract] [Full Text] [PDF]  

Hematology:

Christina Vrettou, Joanne Traeger-Synodinos, Maria Tzetis, George Malamis, and Emmanuel Kanavakis

Rapid Screening of Multiple ß-Globin Gene Mutations by Real-Time PCR on the LightCycler: Application to Carrier Screening and Prenatal Diagnosis of Thalassemia Syndromes
Clin Chem 2003 49: 769-776. [Abstract] [Full Text] [PDF]  

Ramachandran V. Shaji, Eunice Sindhuvi Edison, Balasubramanian Poonkuzhali, Alok Srivastava, and Mammen Chandy

Rapid Detection of ß-Globin Gene Mutations and Polymorphisms by Temporal Temperature Gradient Gel Electrophoresis
Clin Chem 2003 49: 777-781. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Claudia Casini Raggi, Pamela Pinzani, Angelo Paradiso, Mario Pazzagli, and Claudio Orlando

External Quality Assurance Program for PCR Amplification of Genomic DNA: An Italian Experience
Clin Chem 2003 49: 782-791. [Abstract] [Full Text] [PDF]  

Other Areas of Clinical Chemistry:

Jan Hirsch, Axel Menzebach, Ingeborg Dorothea Welters, Gerald Volker Dietrich, Norbert Katz, and Gunter Hempelmann

Indicators of Erythrocyte Damage after Microwave Warming of Packed Red Blood Cells
Clin Chem 2003 49: 792-799. [Abstract] [Full Text] [PDF] Data Supplement  

Technical Briefs:

Wen Wang, Edmond S.K. Ma, Amy Y.Y. Chan, David H.K. Chui, and Samuel S. Chong

Multiple Minisequencing Screen for Seven Southeast Asian Nondeletional -Thalassemia Mutations
Clin Chem 2003 49: 800-803. [Extract] [Full Text] [PDF] Supplemental Data  

Nanda M. Verhoeven, Danielle S.M. Schor, Birthe Roos, Roberta Battini, Sylvia Stöckler-Ipsiroglu, Gajja S. Salomons, and Cornelis Jakobs

Diagnostic Enzyme Assay That Uses Stable-Isotope-labeled Substrates to Detect L-Arginine:Glycine Amidinotransferase Deficiency
Clin Chem 2003 49: 803-805. [Extract] [Full Text] [PDF]  

Kiyotaka Fujita, Linda K. Curtiss, Ikunosuke Sakurabayashi, Fumiko Kameko, Nobuo Okumura, Fumiko Terasawa, Minoru Tozuka, and Tsutomu Katsuyama

Identification and Properties of Glycated Monoclonal IgA That Affect the Fructosamine Assay
Clin Chem 2003 49: 805-808. [Extract] [Full Text] [PDF] Supplemental Tables  

Raj Pandian, Julie Lu, and Jolanta Ossolinska-Plewnia

Fully Automated Chemiluminometric Assay for Hyperglycosylated Human Chorionic Gonadotropin (Invasive Trophoblast Antigen)
Clin Chem 2003 49: 808-810. [Extract] [Full Text] [PDF]  

Yun-Chien Tsen, Guor-Yuan Kao, Chung-Li Chang, Fang-Yu Lai, Chien-Hsun Huang, San Ouyang, Mei-Huei Yu, Chi-Pin Wang, and Y-Neng Chiou

Evaluation and Validation of a Duck IgY Antibody-based Immunoassay for High-Sensitivity C-reactive Protein: Avian Antibody Application in Clinical Diagnostics
Clin Chem 2003 49: 810-813. [Extract] [Full Text] [PDF]  

Frank Saint-Marcoux, Annick Rousseau, Yann Le Meur, Marc Estenne, Christiane Knoop, Jean Debord, and Pierre Marquet

Influence of Sampling-Time Error on Cyclosporine Measurements Nominally at 2 Hours after Administration
Clin Chem 2003 49: 813-815. [Extract] [Full Text] [PDF]  

Giuseppe Castaldo, Paola Nardiello, Fabiana Bellitti, Angiola Rocino, Antonio Coppola, Giovanni di Minno, and Francesco Salvatore

Denaturing HPLC Procedure for Factor IX Gene Scanning
Clin Chem 2003 49: 815-818. [Extract] [Full Text] [PDF]  

M. Rebecca Fokkema, Marleen F. Gilissen, Jasper J. van Doormaal, Marcel Volmer, Ido P. Kema, and Frits A.J. Muskiet

Fasting vs Nonfasting Plasma Homocysteine Concentrations for Diagnosis of Hyperhomocysteinemia
Clin Chem 2003 49: 818-821. [Extract] [Full Text] [PDF]  

Séverine Fruchon, Mounia Bensaid, Nicolas Borot, Marie-Paule Roth, and Hélène Coppin

Use of Denaturing HPLC and a Heteroduplex Generator to Detect the HFE C282Y Mutation Associated with Genetic Hemochromatosis
Clin Chem 2003 49: 822-824. [Extract] [Full Text] [PDF]  

Mark J. Magera, Abby L. Thompson, Dietrich Matern, and Piero Rinaldo

Liquid Chromatography–Tandem Mass Spectrometry Method for the Determination of Vanillylmandelic Acid in Urine
Clin Chem 2003 49: 825-826. [Extract] [Full Text] [PDF]  

So Young Jeong, Kwang Joong Kim, Dong Joon Kim, Sang Wook Oh, and Eui Yul Choi

Sandwich ELISA for Measurement of Cytosolic Aspartate Aminotransferase in Sera from Patients with Liver Diseases
Clin Chem 2003 49: 826-829. [Extract] [Full Text] [PDF]  

Toyofumi Nakanishi, Ken Iguchi, and Akira Shimizu

Method for Hemoglobin A_1c Measurement Based on Peptide Analysis by Electrospray Ionization Mass Spectrometry with Deuterium-labeled Synthetic Peptides as Internal Standards
Clin Chem 2003 49: 829-831. [Extract] [Full Text] [PDF]  

Markus Herrmann, Jürgen Scharhag, Marina Miclea, Axel Urhausen, Wolfgang Herrmann, and Wilfried Kindermann

Post-Race Kinetics of Cardiac Troponin T and I and N-Terminal Pro-Brain Natriuretic Peptide in Marathon Runners
Clin Chem 2003 49: 831-834. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Ann Bowron and David Stansbie

Addition of 3-Deazaadenosine to Vacutainer Tubes Stabilizes Whole-Blood Homocysteine for At Least 6 Hours at Ambient Temperature
Clin Chem 2003 49: 835. [Extract] [Full Text] [PDF]  

Mauro Panteghini and Franca Pagani

On the Comparison of Serum and Plasma Samples in Troponin Assays
Clin Chem 2003 49: 835-836. [Extract] [Full Text] [PDF]  

Ouardia Ben Abdesselam, Josette Vally, Camilo Adem, Marie-José Foglietti, and Jean-Louis Beaudeux

Reference Values for Serum S-100B Protein Depend on the Race of Individuals
Clin Chem 2003 49: 836-837. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Ying Foo

Enzyme Kinetics: A Modern Approach. A.G. Marangoni. New York: John Wiley & Sons, Inc., 244 pp., 89.95, hardcover. ISBN 0-471-15985-9.
Clin Chem 2003 49: 838. [Extract] [Full Text] [PDF]  

Adriaan J.C. van den Brule

Molecular Testing in Laboratory Medicine: Selections from Clinical Chemistry, 1998–2001. David E. Bruns, Y.M. Dennis Lo, and Carl T. Wittwer, eds. Washington, DC: AACC Press, 2002, 376 pp., $59.00 ($47.00 AACC members). ISBN 1-890883-60-3.
Clin Chem 2003 49: 838-839. [Extract] [Full Text] [PDF]  

Robert Rej

WebCitings
Clin Chem 2003 49: 839-840. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2003 49: 841-842. [Extract] [Full Text] [PDF]  

Accent^®:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2003 49: 843-844. [Extract] [Full Text] [PDF]  

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