Editorials:

Kenneth McIntosh

The SARS Coronavirus: Rapid Diagnostics in the Limelight
Clin Chem 2003 49: 845-846. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Junghan Song, Yeomin Yoon, Kyoung Un Park, Junwan Park, Young Joon Hong, Seung Ho Hong, and Jin Q. Kim

Genotype-specific Influence on Nitric Oxide Synthase Gene Expression, Protein Concentrations, and Enzyme Activity in Cultured Human Endothelial Cells
Clin Chem 2003 49: 847-852. [Abstract] [Full Text] [PDF]  

Carl T. Wittwer, Gudrun H. Reed, Cameron N. Gundry, Joshua G. Vandersteen, and Robert J. Pryor

High-Resolution Genotyping by Amplicon Melting Analysis Using LCGreen
Clin Chem 2003 49: 853-860. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

Antonio Carroccio, Giuseppe Iacono, Mario Cottone, Lidia Di Prima, Fabio Cartabellotta, Francesca Cavataio, Calogero Scalici, Giuseppe Montalto, Gaetana Di Fede, GiovamBattista Rini, Alberto Notarbartolo, and Maurizio R. Averna

Diagnostic Accuracy of Fecal Calprotectin Assay in Distinguishing Organic Causes of Chronic Diarrhea from Irritable Bowel Syndrome: A Prospective Study in Adults and Children
Clin Chem 2003 49: 861-867. [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Ling L. Qiu, Stanley S. Levinson, Kristen L. Keeling, and Ronald J. Elin

Convenient and Effective Method for Removing Fibrinogen from Serum Specimens before Protein Electrophoresis
Clin Chem 2003 49: 868-872. [Abstract] [Full Text] [PDF]  

Ralf Labugger, Jeremy A. Simpson, Michelle Quick, Heather A. Brown, Christine E. Collier, Irina Neverova, and Jennifer E. Van Eyk

Strategy for Analysis of Cardiac Troponins in Biological Samples with a Combination of Affinity Chromatography and Mass Spectrometry
Clin Chem 2003 49: 873-879. [Abstract] [Full Text] [PDF]  

Per Venge, Nina Johnston, Bo Lagerqvist, Lars Wallentin, and Bertil Lindahl

Clinical and Analytical Performance of the Liaison Cardiac Troponin I Assay in Unstable Coronary Artery Disease, and the Impact of Age on the Definition of Reference Limits. A FRISC-II Substudy
Clin Chem 2003 49: 880-886. [Abstract] [Full Text] [PDF]  

Sebastian Wesseling, Carsten Stephan, Axel Semjonow, Michael Lein, Brigitte Brux, Pranav Sinha, Stefan A. Loening, and Klaus Jung

Determination of Non-₁-Antichymotrypsin-complexed Prostate-specific Antigen as an Indirect Measurement of Free Prostate-specific Antigen: Analytical Performance and Diagnostic Accuracy
Clin Chem 2003 49: 887-894. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Lina El-Khairy, Stein E. Vollset, Helga Refsum, and Per M. Ueland

Plasma Total Cysteine, Mortality, and Cardiovascular Disease Hospitalizations: The Hordaland Homocysteine Study
Clin Chem 2003 49: 895-900. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Andreas Breidbach, Don H. Catlin, Gary A. Green, Inna Tregub, Henry Truong, and Jeffrey Gorzek

Detection of Recombinant Human Erythropoietin in Urine by Isoelectric Focusing
Clin Chem 2003 49: 901-907. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Matti Ankelo, Annette Westerlund-Karlsson, Jorma Ilonen, Mikael Knip, Kaisa Savola, Pasi Kankaanpää, Liisa Meriö, Harri Siitari, and Ari Hinkkanen

Time-resolved Fluorometric Assay for Detection of Autoantibodies to Glutamic Acid Decarboxylase (GAD65)
Clin Chem 2003 49: 908-915. [Abstract] [Full Text] [PDF]  

Annette Westerlund-Karlsson, Katriina Suonpää, Matti Ankelo, Jorma Ilonen, Mikael Knip, and Ari E. Hinkkanen

Detection of Autoantibodies to Protein Tyrosine Phosphatase-like Protein IA-2 with a Novel Time-resolved Fluorimetric Assay
Clin Chem 2003 49: 916-923. [Abstract] [Full Text] [PDF]  

Shu-jen Yeh, Charles F. Hanna, and Omar S. Khalil

Monitoring Blood Glucose Changes in Cutaneous Tissue by Temperature-modulated Localized Reflectance Measurements
Clin Chem 2003 49: 924-934. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

David G. Grenache, Curtis A. Parvin, and Ann M. Gronowski

Preanalytical Factors That Influence the Abbott TDx Fetal Lung Maturity II Assay
Clin Chem 2003 49: 935-939. [Abstract] [Full Text] [PDF]  

Clinical Immunology:

D. Robert Dufour, Mageli Talastas, Maria D.A. Fernandez, and Barbara Harris

Chemiluminescence Assay Improves Specificity of Hepatitis C Antibody Detection
Clin Chem 2003 49: 940-944. [Abstract] [Full Text] [PDF]  

Nutrition:

Elisabet Miro-Casas, Maria-Isabel Covas, Magi Farre, Montserrat Fito, Jordi Ortuño, Tanja Weinbrenner, Pere Roset, and Rafael de la Torre

Hydroxytyrosol Disposition in Humans
Clin Chem 2003 49: 945-952. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Leo L.M. Poon, On Kei Wong, Winsie Luk, Kwok Yung Yuen, Joseph S.M. Peiris, and Yi Guan

Rapid Diagnosis of a Coronavirus Associated with Severe Acute Respiratory Syndrome (SARS)
Clin Chem 2003 49: 953-955. [Extract] [Full Text] [PDF]  

Juergen Loeffler, Phillipp Swatoch, Diana Akhawi-Araghi, Holger Hebart, and Hermann Einsele

Automated RNA Extraction by MagNA Pure Followed by Rapid Quantification of Cytokine and Chemokine Gene Expression with Use of Fluorescence Resonance Energy Transfer
Clin Chem 2003 49: 955-958. [Extract] [Full Text] [PDF] Data Supplement  

Amitava Dasgupta, Loretta Chow, Gertie Tso, and Lupe Nazareno

Stability of NT-proBNP in Serum Specimens Collected in Becton Dickinson Vacutainer (SST) Tubes
Clin Chem 2003 49: 958-960. [Extract] [Full Text] [PDF]  

Dagmar Schoder, Alois Schmalwieser, Günther Schauberger, Matthias Kuhn, Jeffrey Hoorfar, and Martin Wagner

Physical Characteristics of Six New Thermocyclers
Clin Chem 2003 49: 960-963. [Extract] [Full Text] [PDF]  

Pascale G.A. Van Hoydonck, Evert G. Schouten, and Elisabeth H.M. Temme

Reproducibility of Blood Markers of Oxidative Status and Endothelial Function in Healthy Individuals
Clin Chem 2003 49: 963-965. [Extract] [Full Text] [PDF]  

Mark M. Kushnir, Alan L. Rockwood, Gordon J. Nelson, Alan H. Terry, and A. Wayne Meikle

Liquid Chromatography–Tandem Mass Spectrometry Analysis of Urinary Free Cortisol
Clin Chem 2003 49: 965-967. [Extract] [Full Text] [PDF]  

Diego Gazzolo, Fabrizio Michetti, Matteo Bruschettini, Nora Marchese, Mario Lituania, Salvatore Mangraviti, Enrico Pedrazzi, and Pierluigi Bruschettini

Pediatric Concentrations of S100B Protein in Blood: Age- and Sex-related Changes
Clin Chem 2003 49: 967-970. [Extract] [Full Text] [PDF]  

J. Alan Erickson, Roxann Cousin, James T. Wu, and Edward R. Ashwood

Quantitative Spectrophotometric Microplate Assay for Angiotensin-converting Enzyme in Cerebrospinal Fluid
Clin Chem 2003 49: 970-972. [Extract] [Full Text] [PDF]  

Richie Soong and András Ladányi

Improved Indicators for Assessing the Reliability of Detection and Quantification by Kinetic PCR
Clin Chem 2003 49: 973-976. [Extract] [Full Text] [PDF] Data Supplement  

Thomas Mueller, Alfons Gegenhuber, Werner Poelz, and Meinhard Haltmayer

Comparison of the Biomedica NT-proBNP Enzyme Immunoassay and the Roche NT-proBNP Chemiluminescence Immunoassay: Implications for the Prediction of Symptomatic and Asymptomatic Structural Heart Disease
Clin Chem 2003 49: 976-979. [Extract] [Full Text] [PDF]  

Håkan Karlsson, Claes Guthenberg, Ulrika von Döbeln, and Krister Kristenssson

Extraction of RNA from Dried Blood on Filter Papers after Long-Term Storage
Clin Chem 2003 49: 979-981. [Extract] [Full Text] [PDF]  

Jean-Marc Costa, Alexandra Benachi, Martine Olivi, Yves Dumez, Michel Vidaud, and Evelyne Gautier

Fetal Expressed Gene Analysis in Maternal Blood: A New Tool for Noninvasive Study of the Fetus
Clin Chem 2003 49: 981-983. [Extract] [Full Text] [PDF]  

Katarína Sebeková, Marica Krajcovicová-Kudlácková, Pavol Blazícek, Vojtech Parrák, Reinhard Schinzel, and August Heidland

Functional Hyperhomocysteinemia in Healthy Vegetarians: No Association with Advanced Glycation End Products, Markers of Protein Oxidation, or Lipid Peroxidation after Correction with Vitamin B₁₂
Clin Chem 2003 49: 983-986. [Extract] [Full Text] [PDF]  

Rohit Cariappa, Curtis A. Parvin, and Ann M. Gronowski

Bilirubin in Amniotic Fluid Does Not Interfere with the Abbott TDx FLM II Assay
Clin Chem 2003 49: 986-987. [Extract] [Full Text] [PDF] Data Supplement  

Tomoko Ono, Maki Sogabe, Minoru Ogura, and Fumio Furusaki

Automated Latex Photometric Immunoassay for Total Plasminogen Activator Inhibitor-1 in Plasma
Clin Chem 2003 49: 987-989. [Extract] [Full Text] [PDF]  

Harald H. Kessler, Evelyn Stelzl, Egon Marth, and Rudolf E. Stauber

Detection of Mutations in the Hepatitis B Virus Polymerase Gene
Clin Chem 2003 49: 989-992. [Extract] [Full Text] [PDF]  

Colette Fierens, Dietmar Stöckl, Dimitri Baetens, André P. De Leenheer, and Linda M. Thienpont

Standardization of C-Peptide Measurements in Urine by Method Comparison with Isotope-Dilution Mass Spectrometry
Clin Chem 2003 49: 992-994. [Extract] [Full Text] [PDF]  

Arpad Szallasi, Ann M. Gronowski, and Charles S. Eby

Lamellar Body Count in Amniotic Fluid: A Comparative Study of Four Different Hematology Analyzers
Clin Chem 2003 49: 994-997. [Extract] [Full Text] [PDF]  

Diego Gazzolo, Mario Lituania, Matteo Bruschettini, Pierluigi Bruschettini, and Fabrizio Michetti

S100B Protein Concentrations in Amniotic Fluid Are Higher in Monoamniotic than in Diamniotic Twins and Singleton Pregnancies
Clin Chem 2003 49: 997-999. [Extract] [Full Text] [PDF]  

Attila Tárnok, Jörg Hambsch, Roy Chen, and Rudi Varro

Cytometric Bead Array to Measure Six Cytokines in Twenty-Five Microliters of Serum
Clin Chem 2003 49: 1000-1002. [Extract] [Full Text] [PDF] Data Supplement  

Roxana Marino, Eduardo Chaler, Monica Warman, Marta Ciaccio, Esperanza Berensztein, Marco A. Rivarola, and Alicia Belgorosky

The Serum Growth Hormone (GH) Response to Provocative Tests Is Dependent on Type of Assay in Autosomal Dominant Isolated GH Deficiency because of an ARG¹⁸³HIS (R183H) GH-I Gene Mutation
Clin Chem 2003 49: 1002-1005. [Extract] [Full Text] [PDF] Data Supplement  

Terje Apeland, Mohammad Azam Mansoor, Kristina Pentieva, Helene McNulty, and Roald E. Strandjord

Fasting and Post-Methionine Loading Concentrations of Homocysteine, Vitamin B₂, and Vitamin B₆ in Patients on Antiepileptic Drugs
Clin Chem 2003 49: 1005-1008. [Extract] [Full Text] [PDF]  

Andrea Gaedigk, Darren L. Ryder, L. DiAnne Bradford, and J. Steven Leeder

CYP2D6 Poor Metabolizer Status Can Be Ruled Out by a Single Genotyping Assay for the -1584G Promoter Polymorphism
Clin Chem 2003 49: 1008-1011. [Extract] [Full Text] [PDF] Supplemental Data  

Birgitte Wuyts, Dirk Bernard, Nele Van Den Noortgate, Johan Van De Walle, Bruno Van Vlem, Rita De Smet, Frank De Geeter, Raymond Vanholder, and Joris R. Delanghe

Reevaluation of Formulas for Predicting Creatinine Clearance in Adults and Children, Using Compensated Creatinine Methods
Clin Chem 2003 49: 1011-1014. [Extract] [Full Text] [PDF] Data Supplement  

James W. Chu, Fahim Abbasi, Krishnaji R. Kulkarni, Cynthia Lamendola, Tracey L. McLaughlin, Janet N. Scalisi, and Gerald M. Reaven

Multiple Lipoprotein Abnormalities Associated with Insulin Resistance in Healthy Volunteers Are Identified by the Vertical Auto Profile-II Methodology
Clin Chem 2003 49: 1014-1017. [Extract] [Full Text] [PDF]  

Amy C. Gruszecki, Glen Hortin, John Lam, Diane Kahler, Debbie Smith, Julie Vines, Lee Lancaster, Thomas M. Daly, C. Andrew Robinson, and Robert W. Hardy

Utilization, Reliability, and Clinical Impact of Point-of-Care Testing during Critical Care Transport: Six Years of Experience
Clin Chem 2003 49: 1017-1019. [Extract] [Full Text] [PDF]  

Kathleen L. Caldwell, C. Brook Maxwell, Amir Makhmudov, Sam Pino, Lewis E. Braverman, Robert L. Jones, and Joseph G. Hollowell

Use of Inductively Coupled Plasma Mass Spectrometry to Measure Urinary Iodine in NHANES 2000: Comparison with Previous Method
Clin Chem 2003 49: 1019-1021. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Torsten Arndt

Asialotransferrin—An Alternative to Carbohydrate-deficient Transferrin?
Clin Chem 2003 49: 1022-1023. [Extract] [Full Text] [PDF]  

Hachiro Yamanishi, Shigeru Iyama, Yoshihisa Yamaguchi, Yuzuru Kanakura, and Yoshinori Iwatani

Modification of the Colorimetric Assay for Serum Unsaturated Iron-binding Capacity
Clin Chem 2003 49: 1023-1025. [Extract] [Full Text] [PDF]  

Torsten Arndt, Dorothee Kuhn, Hermann Herbst, Markus Linnemann, and Nikolaos Nikolaidis

Increased Carbohydrate-deficient Transferrin of Unknown Etiology in a 15-Year-Old Male Patient with Autoimmune Hepatitis Type 1
Clin Chem 2003 49: 1025-1026. [Extract] [Full Text] [PDF] Data Supplement  

Angelika de Bree, Véronique Ducros, Louise I. Mennen, Isabelle Queré, Serge Hercberg, and Pilar Galan

Influence of Centrifugation Temperature on the Plasma Total Homocysteine Concentration
Clin Chem 2003 49: 1026-1027. [Extract] [Full Text] [PDF]  

Monika Jung, Silke Klotzek, Michaela Lewandowski, Michael Fleischhacker, and Klaus Jung

Changes in Concentration of DNA in Serum and Plasma during Storage of Blood Samples
Clin Chem 2003 49: 1028-1029. [Extract] [Full Text] [PDF]  

Yuying Tan, Xinghua Sun, Li Tang, Nan Zhang, Qinghong Han, Mingxu Xu, Xuezhong Tan, Xiuying Tan, and Robert M. Hoffman

Automated Enzymatic Assay for Homocysteine
Clin Chem 2003 49: 1029-1030. [Extract] [Full Text] [PDF] Data Supplement  

Book, Software, and Web Site Reviews:

David A. Pearce

Microarray Analysis. Mark Schena. New York: Wiley-Liss, John Wiley & Sons, Inc., 2003, 654 pp., $89.95, hardcover. ISBN 0-471-41443-3.
Clin Chem 2003 49: 1031. [Extract] [Full Text] [PDF]  

Amitava Dasgupta

Analgesics: From Chemistry and Pharmacology to Clinical Applications. H. Buschmann, T. Christoph, E. Friderichs, C. Maul, and B. Sundermann, eds. Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA, 2002, 604 pp., $185.00, hardcover. ISBN 3-527304-03-7.
Clin Chem 2003 49: 1031-1032. [Extract] [Full Text] [PDF]  

Jeffry L. Gehring and Steven H. Hinrichs

Electronic Health Records and Communication for Better Health Care: Proceedings of EuroRec 01. Francois Mennerat, ed. Amsterdam: IOS Press, 2002, 144 pp., $75.00, hardcover. ISBN 1-58603-253-4.
Clin Chem 2003 49: 1032. [Extract] [Full Text] [PDF]  

Robert Rej

WebCitings
Clin Chem 2003 49: 1033. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2003 49: 1034. [Extract] [Full Text] [PDF]  

Accent:

ACCENT® Continuing Education Credit for Readers of Clinical Chemistry
Clin Chem 2003 49: 1035-1036. [Extract] [Full Text] [PDF]  

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