Molecular Diagnostics and Genetics:

Tuangsit Wataganara, Erik S. LeShane, Angela Y. Chen, Lynn Borgatta, Inga Peter, Kirby L. Johnson, and Diana W. Bianchi

Plasma -Globin Gene Expression Suggests that Fetal Hematopoietic Cells Contribute to the Pool of Circulating Cell-Free Fetal Nucleic Acids during Pregnancy
Clin Chem 2004 50: 689-693. [Abstract] [Full Text] [PDF]  

Ourania Nasis, Shanel Thompson, Tom Hong, Margaret Sherwood, Shawn Radcliffe, Laird Jackson, and Tomas Otevrel

Improvement in Sensitivity of Allele-specific PCR Facilitates Reliable Noninvasive Prenatal Detection of Cystic Fibrosis
Clin Chem 2004 50: 694-701. Published online February 5, 2004; 10.1373/clinchem.2003.025981 [Abstract] [Full Text] [PDF]  

Marcus Panning, Marcel Asper, Stefanie Kramme, Herbert Schmitz, and Christian Drosten

Rapid Detection and Differentiation of Human Pathogenic Orthopox Viruses by a Fluorescence Resonance Energy Transfer Real-Time PCR Assay
Clin Chem 2004 50: 702-708. Published online February 12, 2004; 10.1373/clinchem.2003.026781 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Tadaaki Kishi, Antoninus Soosaipillai, Linda Grass, Sheila P. Little, Edward M. Johnstone, and Eleftherios P. Diamandis

Development of an Immunofluorometric Assay and Quantification of Human Kallikrein 7 in Tissue Extracts and Biological Fluids
Clin Chem 2004 50: 709-716. Published online February 5, 2004; 10.1373/clinchem.2003.029538 [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Veronica I. Luzzi, Al N. Saunders, John W. Koenig, John Turk, Stanley F. Lo, Uttam C. Garg, and Dennis J. Dietzen

Analytic Performance of Immunoassays for Drugs of Abuse Below Established Cutoff Values
Clin Chem 2004 50: 717-722. Published online February 5, 2004; 10.1373/clinchem.2003.028878 [Abstract] [Full Text] [PDF]  

Emmanuelle Varlet-Marie, Michael Ashenden, Françoise Lasne, Marie-Therese Sicart, Benedicte Marion, Jacques de Ceaurriz, and Michel Audran

Detection of Hemoglobin-Based Oxygen Carriers in Human Serum for Doping Analysis: Confirmation by Size-Exclusion HPLC
Clin Chem 2004 50: 723-731. Published online February 5, 2004; 10.1373/clinchem.2003.026591 [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Kristian Linnet and Marina Kondratovich

Partly Nonparametric Approach for Determining the Limit of Detection
Clin Chem 2004 50: 732-740. Published online February 5, 2004; 10.1373/clinchem.2003.029983 [Abstract] [Full Text] [PDF] Data Supplement  

Hyunseok Peter Kang, Mitchell G. Scott, Bonnie N. Joe, Vamsi Narra, Jay Heiken, and Curtis A. Parvin

Model for Predicting the Impact of Gadolinium on Plasma Calcium Measured by the o-Cresolphthalein Method
Clin Chem 2004 50: 741-746. Published online February 12, 2004; 10.1373/clinchem.2003.028886 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Pamela Taxel, Pamela M. Fall, Karen M. Prestwood, Lahta Dulipsingh, Debrorah Dauser, Christine Ohannessian, and Lawrence G. Raisz

Changes in Urinary Excretion of Helical Peptide during Therapy for Osteoporosis in Older Adults
Clin Chem 2004 50: 747-750. [Extract] [Full Text] [PDF] Data Supplement  

Zhumei Xu, Shuiping Zhao, Hongnian Zhou, Huijun Ye, and Jiang Li

Atorvastatin Lowers Plasma Matrix Metalloproteinase-9 in Patients with Acute Coronary Syndrome
Clin Chem 2004 50: 750-753. [Extract] [Full Text] [PDF]  

Sara Kim, Mary Reeves, and Michael L. Astion

Web-Based Method for Establishing National Competency Benchmarks in Fourteen Areas of Clinical Laboratory Services
Clin Chem 2004 50: 753-755. [Extract] [Full Text] [PDF]  

Torsten Arndt, Brunhilde Guessregen, Axel Hohl, and Bernd Heicke

Total Plasma Homocysteine Measured by Liquid Chromatography–Tandem Mass Spectrometry with Use of 96-Well Plates
Clin Chem 2004 50: 755-757. [Extract] [Full Text] [PDF] Data Supplement  

K.C. Allen Chan, Lydia C.W. Lit, Eric L.K. Law, Morris H.L. Tai, C.U. Yung, Michael H.M. Chan, and Christopher W.K. Lam

Diminished Urinary Free Cortisol Excretion in Patients with Moderate and Severe Renal Impairment
Clin Chem 2004 50: 757-759. [Extract] [Full Text] [PDF]  

Giorgio Gallinella, Francesca Bonvicini, Claudia Filippone, Stefania Delbarba, Elisabetta Manaresi, Marialuisa Zerbini, and Monica Musiani

Calibrated Real-Time PCR for Evaluation of Parvovirus B19 Viral Load
Clin Chem 2004 50: 759-762. [Extract] [Full Text] [PDF] Data Supplement  

Graham R.D. Jones

Reevaluation of the Power of Error Detection of Westgard Multirules
Clin Chem 2004 50: 762-764. [Extract] [Full Text] [PDF] Data Supplement  

Anand S. Dighe and Patrick M. Sluss

Improved Detection of Serum Estradiol after Sample Extraction Procedure
Clin Chem 2004 50: 764-766. [Extract] [Full Text] [PDF]  

Anand S. Dighe, Frances J. Hayes, Javad Khosravi, Umesh Bodani, and Patrick M. Sluss

Comparison of Inhibin A Immunoassays: Recommendation for Adoption of Standardized Reporting
Clin Chem 2004 50: 767-769. [Extract] [Full Text] [PDF] Data Supplement  

Trevor Lucas, Doris Losert, Matthew Allen, Julius Halaschek-Wiener, Barbara Pratscher, Cornelia Friedrich, Markus Wolschek, Gabriele Fuchsjäger-Mayrl, Leopold Schmetterer, Hubert Pehamberger, Markus Müller, and Volker Wacheck

Combination Allele-Specific Real-Time PCR for Differentiation of ß₂-Adrenergic Receptor Coding Single-Nucleotide Polymorphisms
Clin Chem 2004 50: 769-772. [Extract] [Full Text] [PDF] Data Supplement  

Eugene Dempsey, David E. Barton, and Fergus Ryan

Detection of Five Common CFTR Mutations by Rapid-Cycle Real-Time Amplification Refractory Mutation System PCR
Clin Chem 2004 50: 773-775. [Extract] [Full Text] [PDF]  

Sabrina Frusconi, Betti Giusti, Luciana Rossi, Sara Bernabini, Filippo Poggi, Irene Giotti, Rosanna Abbate, Guglielmina Pepe, and Francesca Torricelli

Improvement of Low-Density Microelectronic Array Technology to Characterize 14 Mutations/Single-Nucleotide Polymorphisms from Several Human Genes on a Large Scale
Clin Chem 2004 50: 775-777. [Extract] [Full Text] [PDF] Data Supplement  

Letters to the Editor:

Frank Z. Stanczyk

Reliability of Extraction/Chromatography RIAs
Clin Chem 2004 50: 778. [Extract] [Full Text] [PDF]  

David A. Herold and Robert L. Fitzgerald

Reliability of Extraction/Chromatography RIAs: Response
Clin Chem 2004 50: 778. [Extract] [Full Text] [PDF]  

Da-elene van der Merwe, Rob Henley, Gary Lane, Rachel Field, Michael Frenneaux, Frank Dunstan, and Ian McDowell

Effect of Different Sample Types and Stability after Blood Collection of N-Terminal Pro-B-Type Natriuretic Peptide as Measured with Roche Elecsys System
Clin Chem 2004 50: 779-780. [Extract] [Full Text] [PDF]  

Sahar Fallouch, Pierre-Jean Lejeune, Jocelyne Barbaria, Pierre Carayon, and Bernard Mallet

Urinary Iodine Analysis: An Alternative Method for Digestion of Urine Samples
Clin Chem 2004 50: 780-782. [Extract] [Full Text] [PDF]  

Raymund Schwan, L. Malet, M.N. Loiseaux, and P.M. Llorca

Which Types of Alcohol-Use Disorder Will Asialotransferrin Detect?
Clin Chem 2004 50: 782. [Extract] [Full Text] [PDF]  

Majid Y. Moridani

Unexpected Relationship between Plasma Homocysteine and Intrauterine Growth Restriction
Clin Chem 2004 50: 782-784. [Extract] [Full Text] [PDF]  

Claire Infante-Rivard and Geroges-Etienne Rivard

Unexpected Relationship between Plasma Homocysteine and Intrauterine Growth Restriction: Response
Clin Chem 2004 50: 784-785. [Extract] [Full Text] [PDF]  

Sven Becker, Graziella Becker-Pergola, Tanja Fehm, Diethelm Wallwiener, and Erich-Franz Solomayer

Time Is an Important Factor when Processing Samples for the Detection of Disseminated Tumor Cells in Blood/Bone Marrow by Reverse Transcription-PCR
Clin Chem 2004 50: 785-786. [Extract] [Full Text] [PDF] Data Supplement  

Ravinder Sodi, Simon Darn, and Anthony Stott

Time for Troponin T? Implications from Newly Elucidated Structure
Clin Chem 2004 50: 786-787. [Extract] [Full Text] [PDF]  

Rianne Luderer, Alice Verheul, and Wouter Kortlandt

Rapid Detection of the Factor V Leiden Mutation by Real-Time PCR with TaqMan Minor Groove Binder Probes
Clin Chem 2004 50: 787-788. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Oswald Sonntag

Clinical Chemistry: Theory, Analysis, Correlation, 4th ed. Lawrence A. Kaplan, Amadeo J. Pesce, and Steven C. Kazmierczak, editors. St. Louis, MO: Mosby, 2003, 1179 pp., $86.95. ISBN 0-323-01716-9 (Book is accompanied by a CD-ROM).
Clin Chem 2004 50: 789-790. [Extract] [Full Text] [PDF]  

Salvador F. Sena

Principles of Forensic Toxicology. Second Edition. Barry Levine, ed. Washington, DC: AACC, 2003, 385 pp., $67.00 ($54.00 AACC members), softcover. ISBN 1-890883-87-5.
Clin Chem 2004 50: 790. [Extract] [Full Text] [PDF]  

Corrections:

Correction for Volume 50, Issue , p. 288
Clin Chem 2004 50: 788. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Clin Chem 2004 50: 791-792. [Extract] [Full Text] [PDF]  

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