Editorials:

Xavier de Lamballerie and Philippe Colson

The Battle against Infectious Diseases in Developing Countries: The Inseparable Twins of Diagnosis and Therapy
Clin Chem 2006 52: 1217. [Extract] [Full Text] [PDF]  

Minireview:

Glen L. Hortin, Saeed A. Jortani, James C. Ritchie, Jr, Roland Valdes, Jr, and Daniel W. Chan

Proteomics: A New Diagnostic Frontier
Clin Chem 2006 52: 1218-1222. Published online May 4, 2006; 10.1373/clinchem.2006.067280 [Abstract] [Full Text] [PDF]  

Reviews:

Glen L. Hortin

The MALDI-TOF Mass Spectrometric View of the Plasma Proteome and Peptidome
Clin Chem 2006 52: 1223-1237. Published online April 27, 2006; 10.1373/clinchem.2006.069252 [Abstract] [Full Text] [PDF]  

Hassan M.E. Azzazy, Mai M.H. Mansour, and Steven C. Kazmierczak

Nanodiagnostics: A New Frontier for Clinical Laboratory Medicine
Clin Chem 2006 52: 1238-1246. Published online May 18, 2006; 10.1373/clinchem.2006.066654 [Abstract] [Full Text] [PDF]  

Ursula Meier, Olav Gressner, Frank Lammert, and Axel M. Gressner

Gc-Globulin: Roles in Response to Injury
Clin Chem 2006 52: 1247-1253. Published online May 18, 2006; 10.1373/clinchem.2005.065680 [Abstract] [Full Text] [PDF]  

Point/Counterpoint:

Nader Rifai, Christie M. Ballantyne, Mary Cushman, Daniel Levy, and Gary L. Myers

Point: High-Sensitivity C-Reactive Protein and Cardiac C-Reactive Protein Assays: Is There a Need to Differentiate?
Clin Chem 2006 52: 1254-1256. [Extract] [Full Text] [PDF]  

James V. Callaghan and Steven I. Gutman

Counterpoint: Food and Drug Administration Guidance for C-Reactive Protein Assays: Matching Claims with Performance Data
Clin Chem 2006 52: 1256-1257. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Christian Drosten, Marcus Panning, Jan Felix Drexler, Florian Hänsel, Celia Pedroso, Jane Yeats, Luciano Kleber de Souza Luna, Matthew Samuel, Britta Liedigk, Ute Lippert, Martin Stürmer, Hans Wilhelm Doerr, Carlos Brites, and Wolfgang Preiser

Ultrasensitive Monitoring of HIV-1 Viral Load by a Low-Cost Real-Time Reverse Transcription-PCR Assay with Internal Control for the 5' Long Terminal Repeat Domain
Clin Chem 2006 52: 1258-1266. Published online April 20, 2006; 10.1373/clinchem.2006.066498 [Abstract] [Full Text] [PDF] 066498.Supplemental Data  

Ilka Warshawsky, Olga B. Chernova, Christian A. Hübner, Reinhard Stindl, Marco Henneke, Andreas Gal, and Marvin R. Natowicz

Multiplex Ligation-Dependent Probe Amplification for Rapid Detection of Proteolipid Protein 1 Gene Duplications and Deletions in Affected Males and Carrier Females with Pelizaeus–Merzbacher Disease
Clin Chem 2006 52: 1267-1275. Published online April 27, 2006; 10.1373/clinchem.2006.067967 [Abstract] [Full Text] [PDF] 067967.Supplemental Data  

Melinda Procter, Lan-Szu Chou, Wei Tang, Mohamed Jama, and Rong Mao

Molecular Diagnosis of Prader–Willi and Angelman Syndromes by Methylation-Specific Melting Analysis and Methylation-Specific Multiplex Ligation-Dependent Probe Amplification
Clin Chem 2006 52: 1276-1283. Published online May 11, 2006; 10.1373/clinchem.2006.067603 [Abstract] [Full Text] [PDF]  

Kristian Kofoed, Uffe Vest Schneider, Troels Scheel, Ove Andersen, and Jesper Eugen-Olsen

Development and Validation of a Multiplex Add-On Assay for Sepsis Biomarkers Using xMAP Technology
Clin Chem 2006 52: 1284-1293. Published online May 11, 2006; 10.1373/clinchem.2006.067595 [Abstract] [Full Text] [PDF]  

Zhi Zheng, Yuling Luo, and Gary K. McMaster

Sensitive and Quantitative Measurement of Gene Expression Directly from a Small Amount of Whole Blood
Clin Chem 2006 52: 1294-1302. Published online May 18, 2006; 10.1373/clinchem.2005.065078 [Abstract] [Full Text] [PDF] 065078.Supplemental Data  

Pamela Kepper, Richard Reinhardt, Andreas Dahl, Hans Lehrach, and Sascha Sauer

Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of DNA on Microarrays
Clin Chem 2006 52: 1303-1310. Published online May 25, 2006; 10.1373/clinchem.2006.067264 [Abstract] [Full Text] [PDF] 067264.Supplemental Data  

Automation and Analytical Techniques:

Chiung-Wen Hu, Chien-Jen Wang, Louis W. Chang, and Mu-Rong Chao

Clinical-Scale High-Throughput Analysis of Urinary 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine by Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry with On-Line Solid-Phase Extraction
Clin Chem 2006 52: 1381-1388. Published online May 11, 2006; 10.1373/clinchem.2005.063735 [Abstract] [Full Text] [PDF]  

Zhiliang Jiang, Shuangjiao Sun, Aihui Liang, Wenxin Huang, and Aimiao Qin

Gold-Labeled Nanoparticle-Based Immunoresonance Scattering Spectral Assay for Trace Apolipoprotein AI and Apolipoprotein B
Clin Chem 2006 52: 1389-1394. [Abstract] [Full Text] [PDF] 061176.Supplemental Data  

Marlies Oostendorp, Udo F.H. Engelke, Michèl A.A.P. Willemsen, and Ron A. Wevers

Diagnosing Inborn Errors of Lipid Metabolism with Proton Nuclear Magnetic Resonance Spectroscopy
Clin Chem 2006 52: 1395-1405. Published online May 18, 2006; 10.1373/clinchem.2006.069112 [Abstract] [Full Text] [PDF] 069112.Supplemental data  

Evidence-Based Laboratory Medicine and Test Utilization:

Gunn B.B. Kristensen, Kari Nerhus, Geir Thue, and Sverre Sandberg

Results and Feasibility of an External Quality Assessment Scheme for Self-Monitoring of Blood Glucose
Clin Chem 2006 52: 1311-1317. Published online May 11, 2006; 10.1373/clinchem.2006.068114 [Abstract] [Full Text] [PDF]  

Hemostasis and Thrombosis:

Anna Maria Gori, Francesco Sofi, Anna Maria Corsi, Alessandra Gazzini, Ilaria Sestini, Fulvio Lauretani, Stefania Bandinelli, Gian Franco Gensini, Luigi Ferrucci, and Rosanna Abbate

Predictors of Vitamin B₆ and Folate Concentrations in Older Persons: The InCHIANTI Study
Clin Chem 2006 52: 1318-1324. Published online May 11, 2006; 10.1373/clinchem.2005.066217 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Sarah D. de Ferranti, Kimberlee Gauvreau, David S. Ludwig, Jane W. Newburger, and Nader Rifai

Inflammation and Changes in Metabolic Syndrome Abnormalities in US Adolescents: Findings from the 1988–1994 and 1999–2000 National Health and Nutrition Examination Surveys
Clin Chem 2006 52: 1325-1330. Published online May 4, 2006; 10.1373/clinchem.2006.067181 [Abstract] [Full Text] [PDF]  

James P. Corsetti, David L. Rainwater, Arthur J. Moss, Wojciech Zareba, and Charles E. Sparks

High Lipoprotein-Associated Phospholipase A₂ Is a Risk Factor for Recurrent Coronary Events in Postinfarction Patients
Clin Chem 2006 52: 1331-1338. Published online May 18, 2006; 10.1373/clinchem.2006.066845 [Abstract] [Full Text] [PDF]  

Michael W. Clarke, Amanda J. Hooper, Henrietta A. Headlam, Jason H.Y. Wu, Kevin D. Croft, and John R. Burnett

Assessment of Tocopherol Metabolism and Oxidative Stress in Familial Hypobetalipoproteinemia
Clin Chem 2006 52: 1339-1345. Published online May 25, 2006; 10.1373/clinchem.2006.068692 [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Oscar Quintela, François-Ludovic Sauvage, Fabienne Charvier, Jean-Michel Gaulier, Gérard Lachâtre, and Pierre Marquet

Liquid Chromatography–Tandem Mass Spectrometry for Detection of Low Concentrations of 21 Benzodiazepines, Metabolites, and Analogs in Urine: Method with Forensic Applications
Clin Chem 2006 52: 1346-1355. Published online May 18, 2006; 10.1373/clinchem.2005.065631 [Abstract] [Full Text] [PDF] 065631.Supplemental Data  

Endocrinology and Metabolism:

Margrita H. Slagter, Louis J.G. Gooren, Willem de Ronde, Antoninus Soosaipillai, Andreas Scorilas, Erik J. Giltay, Miltiadis Paliouras, and Eleftherios P. Diamandis

Serum and Urine Tissue Kallikrein Concentrations in Male-to-Female Transsexuals Treated with Antiandrogens and Estrogens
Clin Chem 2006 52: 1356-1365. Published online April 27, 2006; 10.1373/clinchem.2006.068932 [Abstract] [Full Text] [PDF] 068932.Supplemental Tables 1-9  

Lucille Kavanagh, T. Joseph McKenna, Michael N. Fahie-Wilson, James Gibney, and Thomas P. Smith

Specificity and Clinical Utility of Methods for the Detection of Macroprolactin
Clin Chem 2006 52: 1366-1372. Published online May 4, 2006; 10.1373/clinchem.2005.065854 [Abstract] [Full Text] [PDF]  

Raul Zamora-Ros, Mireia Urpí-Sardà, Rosa M. Lamuela-Raventós, Ramón Estruch, Mónica Vázquez-Agell, Manuel Serrano-Martínez, Walter Jaeger, and Cristina Andres-Lacueva

Diagnostic Performance of Urinary Resveratrol Metabolites as a Biomarker of Moderate Wine Consumption
Clin Chem 2006 52: 1373-1380. Published online May 4, 2006; 10.1373/clinchem.2005.065870 [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Ranieri Rossi, Isabella Dalle-Donne, Aldo Milzani, and Daniela Giustarini

Oxidized Forms of Glutathione in Peripheral Blood as Biomarkers of Oxidative Stress
Clin Chem 2006 52: 1406-1414. Published online May 11, 2006; 10.1373/clinchem.2006.067793 [Abstract] [Full Text] [PDF] 067793.Supplemental Data  

Pediatric Clinical Chemistry:

Angelika Hammerer-Lercher, Ralf Geiger, Johannes Mair, Christoph Url, Gerald Tulzer, Evelyn Lechner, Bernd Puschendorf, and Rudolf Sommer

Utility of N-Terminal Pro-B-Type Natriuretic Peptide to Differentiate Cardiac Diseases from Noncardiac Diseases in Young Pediatric Patients
Clin Chem 2006 52: 1415-1419. Published online May 11, 2006; 10.1373/clinchem.2005.060608 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Mohammad Reza Abdollahi, Philip A.I. Guthrie, George Davey Smith, Debbie A. Lawlor, Shah Ebrahim, and Ian N.M. Day

Integrated Single-Label Liquid-Phase Assay of APOE Codons 112 and 158 and a Lipoprotein Study in British Women,
Clin Chem 2006 52: 1420-1423. Published online April 27, 2006; 10.1373/clinchem.2006.067082 [Abstract] [Full Text] [PDF] 067082.Supplemental Data Table 1  

Masako Moriyama, Nobuhide Hayashi, Chinami Ohyabu, Masahiko Mukai, Seiji Kawano, and Shunichi Kumagai

Performance Evaluation and Cross-Reactivity from Insulin Analogs with the ARCHITECT Insulin Assay,
Clin Chem 2006 52: 1423-1426. Published online May 11, 2006; 10.1373/clinchem.2005.065995 [Abstract] [Full Text] [PDF]  

Ekkehard Schütz, Melanie Scharfenstein, and Bertram Brenig

Genotyping of Ovine Prion Protein Gene (PRNP) Variants by PCR with Melting Curve Analysis,
Clin Chem 2006 52: 1426-1429. Published online May 11, 2006; 10.1373/clinchem.2006.069666 [Abstract] [Full Text] [PDF] 069666.Supplemental Data  

Letters to the Editor:

Raffaele Iorio, Antonietta Giannattasio, Ester Lamberti, Claudia Della Corte, Emanuele Nicastro, and Maria Immacolata Spagnuolo

Hyper--Glutamyltransferase Is Commonly Present in Non–Breast-Fed Infants with Biliary Atresia Successfully Treated with Portoenterostomy
Clin Chem 2006 52: 1430. [Extract] [Full Text] [PDF]  

Stratis Avrameas

Historical Background of the Invention of EIA and ELISA
Clin Chem 2006 52: 1430-1431. [Extract] [Full Text] [PDF]  

Rudolf M. Lequin

The author of the article cited above responds:
Clin Chem 2006 52: 1431. [Extract] [Full Text] [PDF]  

Francesca Pizzolo, Angela Corgnati, Patrizia Guarini, Chiara Pavan, Antonella Bassi, Roberto Corrocher, and Oliviero Olivieri

Plasma Aldosterone Assays: Comparison between Chemiluminescence-Based and RIA Methods
Clin Chem 2006 52: 1431-1432. [Extract] [Full Text] [PDF]  

Pedro V. Baptista, Maria Koziol-Montewka, Jolanta Paluch-Oles, Gonçalo Doria, and Ricardo Franco

Gold-Nanoparticle-Probe–Based Assay for Rapid and Direct Detection of Mycobacterium tuberculosis DNA in Clinical Samples
Clin Chem 2006 52: 1433-1434. [Extract] [Full Text] [PDF]  

Abdul Jaleel, Barbara A.L. Owen, Michelle K. Manske, Jerry A. Katzmann, Robert A. Kyle, and Roshini S. Abraham

Bence Jones Cryoglobulinuria: Characterization of a Urinary Light Chain Cryoglobulin
Clin Chem 2006 52: 1435-1436. [Extract] [Full Text] [PDF]  

Pierre Sidon, Pierre Heimann, Frédéric Lambert, Barbara Dessars, Valérie Robin, and Hakim El Housni

Combined Locked Nucleic Acid and Molecular Beacon Technologies for Sensitive Detection of the JAK2^V617F Somatic Single-Base Sequence Variant
Clin Chem 2006 52: 1436-1438. [Extract] [Full Text] [PDF] Supplemental Data 066886.Data Supplements  

Julie Decock

How Accurate Is the Antiprimer Quenching-Based Real-Time PCR for Detection of Her2/neu in Clinical Cancer Samples?
Clin Chem 2006 52: 1438-1439. [Extract] [Full Text] [PDF]  

Osama Alsmadi, Fadi Alkayal, MoeenAldeen Al-Sayed, Mohamed S. Rashed, Faiqa Imtiaz, and Brian F. Meyer

LCGreen I–Based Real-Time PCR Assays for Detecting Common ASL and HMGCL Variants
Clin Chem 2006 52: 1439-1440. [Extract] [Full Text] [PDF] 067538.Supplemental Data  

Iman J. Schultz, Lambertus A. Kiemeney, Johannes L. Willems, Dorine W. Swinkels, J. Alfred Witjes, and Jacques B. de Kok

Survivin and MKI67 mRNA Expression in Bladder Washings of Patients with Superficial Urothelial Cell Carcinoma Correlate with Tumor Stage and Grade but Do Not Predict Tumor Recurrence
Clin Chem 2006 52: 1440-1442. [Extract] [Full Text] [PDF] 071480.Supplementary Data  

Giuseppe Lippi, Antonella Bassi, Giorgio Brocco, Martina Montagnana, Gian Luca Salvagno, and Gian Cesare Guidi

Preanalytic Error Tracking in a Laboratory Medicine Department: Results of a 1-Year Experience
Clin Chem 2006 52: 1442-1443. [Extract] [Full Text] [PDF]  

Maria Erali, June I. Pounder, Gail L. Woods, Cathy A. Petti, and Carl T. Wittwer

Multiplex Single-Color PCR with Amplicon Melting Analysis for Identification of Aspergillus Species
Clin Chem 2006 52: 1443-1445. [Extract] [Full Text] [PDF] Supplemental Data 068510.Supplemental Data  

Seung-Tae Lee, Myong Soo Kim, Dae Yong Choi, Sun Kyung Kim, and Chang-Seok Ki

Incidence of Variant Hemoglobin (Hb) and Increased Fetal Hb Concentrations and Their Effect on Hb A_1c Measurement in a Korean Population
Clin Chem 2006 52: 1445-1446. [Extract] [Full Text] [PDF]  

Qiuying Huang, Yangjian Cheng, Qiwei Guo, and Qingge Li

Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple Virus Assays
Clin Chem 2006 52: 1446-1448. [Extract] [Full Text] [PDF] 069971.Supplemental Data  

Josefina Mora, Eulàlia Urgell, Antoni Farré, Laia Comas, Enric Montserrat, and Francesc González-Sastre

Agreement between K-ras Sequence Variations Detected in Plasma and Tissue DNA in Pancreatic and Colorectal Cancer
Clin Chem 2006 52: 1448-1449. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

David E. Bruns

The Clinical Chemist
Clin Chem 2006 52: 1450-1455. [Extract] [Full Text] [PDF]  

David E. Bruns

Professor Martin I. Rubin: A Personal Remembrance
Clin Chem 2006 52: 1455-1456. [Extract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.