Editorials:

Kenji Hashimoto

CSF Serine Enantiomers and Glycine in the Study of Neurologic and Psychiatric Disorders
Clin Chem 2008 54: 1413-1414. [Extract] [Full Text] [PDF]  

Rafael M. Nagler

Saliva Analysis for Monitoring Dialysis and Renal Function
Clin Chem 2008 54: 1415-1417. [Extract] [Full Text] [PDF]  

Rob M. van Dam

Coffee Consumption and Coronary Heart Disease: Paradoxical Effects on Biological Risk Factors versus Disease Incidence
Clin Chem 2008 54: 1418-1420. [Extract] [Full Text] [PDF]  

Perspective:

Christopher P. Price and Robert H. Christenson

Evaluating New Diagnostic Technologies: Perspectives in the UK and US
Clin Chem 2008 54: 1421-1423. [Extract] [Full Text] [PDF]  

Mini-Review:

Marc P. Bonaca and David A. Morrow

Defining a Role for Novel Biomarkers in Acute Coronary Syndromes
Clin Chem 2008 54: 1424-1431. Published online July 18, 2008; 10.1373/clinchem.2008.105387 [Abstract] [Full Text] [PDF]  

Review:

Allan S. Jaffe

Key Issues in the Developing Synergism between Cardiovascular Imaging and Biomarkers
Clin Chem 2008 54: 1432-1442. Published online August 1, 2008; 10.1373/clinchem.2008.106138 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Sabine A. Fuchs, Monique G. M. de Sain-van der Velden, Martina M. J. de Barse, Martin W. Roeleveld, Margriet Hendriks, Lambertus Dorland, Leo W. J. Klomp, Ruud Berger, and Tom J. de Koning

Two Mass-Spectrometric Techniques for Quantifying Serine Enantiomers and Glycine in Cerebrospinal Fluid: Potential Confounders and Age-Dependent Ranges
Clin Chem 2008 54: 1443-1450. Published online July 7, 2008; 10.1373/clinchem.2007.100412 [Abstract] [Full Text] [PDF] Supplement  

Paul E. Minkler, Maria S. K. Stoll, Stephen T. Ingalls, Shuming Yang, Janos Kerner, and Charles L. Hoppel

Quantification of Carnitine and Acylcarnitines in Biological Matrices by HPLC Electrospray Ionization– Mass Spectrometry
Clin Chem 2008 54: 1451-1462. Published online August 4, 2008; 10.1373/clinchem.2007.099226 [Abstract] [Full Text] [PDF] Supplement  

Ruta Svobaite, Isabelle Solassol, Frederic Pinguet, Liudas Ivanauskas, Janine Brès, and Françoise M. M. Bressolle

HPLC with UV or Mass Spectrometric Detection for Quantifying Endogenous Uracil and Dihydrouracil in Human Plasma
Clin Chem 2008 54: 1463-1472. Published online July 17, 2008; 10.1373/clinchem.2007.102251 [Abstract] [Full Text] [PDF] Supplement  

Timothy M. Blicharz, David M. Rissin, Michaela Bowden, Ryan B. Hayman, Christopher DiCesare, Jasvinder S. Bhatia, Nerline Grand-Pierre, Walter L. Siqueira, Eva J. Helmerhorst, Joseph Loscalzo, Frank G. Oppenheim, and David R. Walt

Use of Colorimetric Test Strips for Monitoring the Effect of Hemodialysis on Salivary Nitrite and Uric Acid in Patients with End-Stage Renal Disease: A Proof of Principle
Clin Chem 2008 54: 1473-1480. Published online August 1, 2008; 10.1373/clinchem.2008.105320 [Abstract] [Full Text] [PDF] Supplement  

Jie Wu, Feng Yan, Xiaoqing Zhang, Yuetian Yan, Jinhai Tang, and Huangxian Ju

Disposable Reagentless Electrochemical Immunosensor Array Based on a Biopolymer/Sol-Gel Membrane for Simultaneous Measurement of Several Tumor Markers
Clin Chem 2008 54: 1481-1488. Published online July 7, 2008; 10.1373/clinchem.2007.102350 [Abstract] [Full Text] [PDF] Supplemental Data  

Nutrition:

Arve Ulvik, Stein Emil Vollset, Geir Hoff, and Per Magne Ueland

Coffee Consumption and Circulating B-Vitamins in Healthy Middle-Aged Men and Women
Clin Chem 2008 54: 1489-1496. Published online July 7, 2008; 10.1373/clinchem.2008.103465 [Abstract] [Full Text] [PDF] Supplemental Data  

General Clinical Chemistry:

Dan Zhang, Thomas Lavaux, Anne-Claire Voegeli, Thierry Lavigne, Vincent Castelain, Nicolas Meyer, Rémy Sapin, Dominique Aunis, Marie-Hélène Metz-Boutigue, and Francis Schneider

Prognostic Value of Chromogranin A at Admission in Critically Ill Patients: A Cohort Study in a Medical Intensive Care Unit
Clin Chem 2008 54: 1497-1503. Published online July 17, 2008; 10.1373/clinchem.2007.102442 [Abstract] [Full Text] [PDF]  

Aisha Shaikh, Jesse C. Seegmiller, Timothy M. Borland, Bradley E. Burns, Paula M. Ladwig, Ravinder J. Singh, Rajiv Kumar, Timothy S. Larson, and John C. Lieske

Comparison between Immunoturbidimetry, Size-Exclusion Chromatography, and LC-MS to Quantify Urinary Albumin
Clin Chem 2008 54: 1504-1510. Published online July 10, 2008; 10.1373/clinchem.2008.107508 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Natalia N. Tamm, Karina R. Seferian, Alexander G. Semenov, Kadriya S. Mukharyamova, Ekaterina V. Koshkina, Mihail I. Krasnoselsky, Alexander B. Postnikov, Daria V. Serebryanaya, Fred S. Apple, MaryAnn M. Murakami, and Alexey G. Katrukha

Novel Immunoassay for Quantification of Brain Natriuretic Peptide and Its Precursor in Human Blood
Clin Chem 2008 54: 1511-1518. Published online July 7, 2008; 10.1373/clinchem.2007.100545 [Abstract] [Full Text] [PDF] Supplemental Data  

Drug Monitoring and Toxicology:

François-Ludovic Sauvage, Jean-Michel Gaulier, Gérard Lachâtre, and Pierre Marquet

Pitfalls and Prevention Strategies for Liquid Chromatography-Tandem Mass Spectrometry in the Selected Reaction– Monitoring Mode for Drug Analysis
Clin Chem 2008 54: 1519-1527. Published online July 17, 2008; 10.1373/clinchem.2008.105478 [Abstract] [Full Text] [PDF] Supplemental Data  

Molecular Diagnostics and Genetics:

K. C. Allen Chan, Paul B. S. Lai, Tony S. K. Mok, Henry L. Y. Chan, Chunming Ding, S. W. Yeung, and Y. M. Dennis Lo

Quantitative Analysis of Circulating Methylated DNA as a Biomarker for Hepatocellular Carcinoma
Clin Chem 2008 54: 1528-1536. Published online July 24, 2008; 10.1373/clinchem.2008.104653 [Abstract] [Full Text] [PDF]  

Andreas Weinhaeusel, Susanne Thiele, Manuela Hofner, Olaf Hiort, and Christa Noehammer

PCR-Based Analysis of Differentially Methylated Regions of GNAS Enables Convenient Diagnostic Testing of Pseudohypoparathyroidism Type Ib
Clin Chem 2008 54: 1537-1545. Published online July 10, 2008; 10.1373/clinchem.2008.104216 [Abstract] [Full Text] [PDF] Supplemental Data  

Endocrinology and Metabolism:

Marius E. Kraenzlin, Claude A. Kraenzlin, Christian Meier, Cecilia Giunta, and Beat Steinmann

Automated HPLC Assay for Urinary Collagen Cross-links: Effect of Age, Menopause, and Metabolic Bone Diseases
Clin Chem 2008 54: 1546-1553. Published online July 24, 2008; 10.1373/clinchem.2008.105262 [Abstract] [Full Text] [PDF] Supplemental Data  

Aurélie Claudon, Philippe Vergnaud, Cécile Valverde, Anita Mayr, Ursula Klause, and Patrick Garnero

New Automated Multiplex Assay for Bone Turnover Markers in Osteoporosis
Clin Chem 2008 54: 1554-1563. Published online August 1, 2008; 10.1373/clinchem.2008.105866 [Abstract] [Full Text] [PDF]  

Brief Communications:

Catherine Costa, Jean-Marc Costa, Josiane Martin, Brigitte Boissier, Michel Goossens, and Emmanuelle Girodon

Multiplex Allele-Specific Fluorescent PCR for Haplotyping the IVS8 (TG)_m(T)_n Locus in the CFTR Gene
Clin Chem 2008 54: 1564-1567. [Abstract] [Full Text] [PDF]  

David M. Ross, Dale B. Watkins, Timothy P. Hughes, and Susan Branford

Reverse Transcription with Random Pentadecamer Primers Improves the Detection Limit of a Quantitative PCR Assay for BCR-ABL Transcripts in Chronic Myeloid Leukemia: Implications for Defining Sensitivity in Minimal Residual Disease
Clin Chem 2008 54: 1568-1571. Published online July 18, 2008; 10.1373/clinchem.2008.105916 [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Case Study:

Joris R. Delanghe, Marc L. De Buyzere, Veerle Casneuf, and Marc Peeters

Unusual Serum Electrophoresis Pattern in a Woman with Pancreatic Carcinoma
Clin Chem 2008 54: 1572-1574. [Extract] [Full Text] [PDF]  

Jerry A. Katzmann

Commentary
Clin Chem 2008 54: 1574-1575. [Extract] [Full Text] [PDF]  

Jim D. Faix

Commentary
Clin Chem 2008 54: 1575. [Extract] [Full Text] [PDF]  

Citation Classic:

Hugo A. Katus

Development of the Cardiac Troponin T Immunoassay
Clin Chem 2008 54: 1576-1577. [Extract] [Full Text] [PDF]  

Inspiring Minds:

Misia Landau

Gerald Cooper
Clin Chem 2008 54: 1578-1579. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Thomas R. Haven, Bradley W. Lyons, Brian M. Pasi, Lily L. Wu, Mark E. Astill, and Harry R Hill

Effect of Acetylcholine Receptor Source on Detection and Quantification of Anti–Acetylcholine Receptor–Binding Antibody
Clin Chem 2008 54: 1580-1581. [Extract] [Full Text] [PDF]  

Harvey Mamon, Carlos Hader, Jin Li, Lilin Wang, Matthew Kulke, Giulia Amicarelli, Erlet Shehi, Daniel Adlerstein, Kristin Roper, Leah Killion, Susanne Hooshmand, and G. Mike Makrigiorgos

Preferential Amplification of Apoptotic DNA from Plasma: Potential for Enhancing Detection of Minor DNA Alterations in Circulating DNA
Clin Chem 2008 54: 1582-1584. [Extract] [Full Text] [PDF]  

Uwe Kobold, Thomas Dülffer, Markus Dangl, Achim Escherich, Manfred Kubbies, Ralf Röddiger, and Jo Anne Wright

Quantification of Hepcidin-25 in Human Serum by Isotope Dilution Micro-HPLC–Tandem Mass Spectrometry
Clin Chem 2008 54: 1584-1586. [Extract] [Full Text] [PDF]  

Vivek Kumar and Brad S. Karon

Comparison of Measured and Calculated Bicarbonate Values
Clin Chem 2008 54: 1586-1587. [Extract] [Full Text] [PDF]  

Linda M. Thienpont

Calculation of Measurement Uncertainty—Why Bias Should Be Treated Separately
Clin Chem 2008 54: 1587-1588. [Extract] [Full Text] [PDF]  

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